The cortical innate immune response increases local neuronal excitability leading to seizures.
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Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1betaEpilepsy and innate immune system: A possible immunogenic predisposition and related therapeutic implicationsNeuroimaging biomarkers for epilepsy: advances and relevance to glial cellsTNF-overexpression in Borna disease virus-infected mouse brains triggers inflammatory reaction and epileptic seizuresAcute neuroimmune modulation attenuates the development of anxiety-like freezing behavior in an animal model of traumatic brain injuryToll-like receptor 4 enhancement of non-NMDA synaptic currents increases dentate excitability after brain injury.A swell in the armamentarium of antiepileptic drug targetsMicroglial ablation and lipopolysaccharide preconditioning affects pilocarpine-induced seizures in mice.The Peptide Network between Tetanus Toxin and Human Proteins Associated with Epilepsy.Decoy peptide targeted to Toll-IL-1R domain inhibits LPS and TLR4-active metabolite morphine-3 glucuronide sensitization of sensory neurons.Acute lipopolysaccharide exposure facilitates epileptiform activity via enhanced excitatory synaptic transmission and neuronal excitability in vitro.Role of inflammatory mediators in the pathogenesis of epilepsy.The impact of microglial activation on blood-brain barrier in brain diseases.Evidence for a developmental role for TLR4 in learning and memory.Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia.Microglia activation triggers astrocyte-mediated modulation of excitatory neurotransmission.Priming of adult pain responses by neonatal pain experience: maintenance by central neuroimmune activity.Tumor necrosis factor-α-mediated threonine 435 phosphorylation of p65 nuclear factor-κB subunit in endothelial cells induces vasogenic edema and neutrophil infiltration in the rat piriform cortex following status epilepticus.The Cancer Chemotherapeutic Paclitaxel Increases Human and Rodent Sensory Neuron Responses to TRPV1 by Activation of TLR4Cytokines and brain excitability.Does brain inflammation mediate pathological outcomes in epilepsy?Platelet-activating factor receptor antagonism targets neuroinflammation in experimental epilepsyPostnatal activation of TLR4 in astrocytes promotes excitatory synaptogenesis in hippocampal neurons.The ADAR RNA editing enzyme controls neuronal excitability in Drosophila melanogaster.Intracellular calcium signalling in Alzheimer's diseaseInflammation in epilepsy: clinical observations.Astrocyte immune responses in epilepsy.The role of inflammation in epileptogenesis.Pathophysiogenesis of mesial temporal lobe epilepsy: is prevention of damage antiepileptogenic?Immune mechanisms in epileptogenesis.Inflammatory pathways of seizure disorders.Network-wide dysregulation of calcium homeostasis in Alzheimer's disease.Identification of novel gene and pathway targets for human epilepsy treatment.Modulation of neuronal excitability by immune mediators in epilepsy.Exploring novel AEDs from drugs used for treatment of non-epileptic disorders.Microglia-Neuron Communication in Epilepsy.Transient and chronic seizure-induced inflammation in human focal epilepsy.Pharmacological Tools to Activate Microglia and their Possible use to Study Neural Network Patho-physiology.Impairment of in vivo calcium signaling in amyloid plaque-associated microglia.Comparative clinical characteristics of early- and adult-onset multiple sclerosis patients with seizures.
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The cortical innate immune response increases local neuronal excitability leading to seizures.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 30 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The cortical innate immune res ...... itability leading to seizures.
@en
The cortical innate immune res ...... itability leading to seizures.
@nl
type
label
The cortical innate immune res ...... itability leading to seizures.
@en
The cortical innate immune res ...... itability leading to seizures.
@nl
prefLabel
The cortical innate immune res ...... itability leading to seizures.
@en
The cortical innate immune res ...... itability leading to seizures.
@nl
P2093
P2860
P356
P1433
P1476
The cortical innate immune res ...... itability leading to seizures.
@en
P2093
Alexis Northcutt
Daniel S Barth
Krista M Rodgers
Steven F Maier
P2860
P304
P356
10.1093/BRAIN/AWP177
P407
P577
2009-06-30T00:00:00Z