Advances in antisense oligonucleotide development for target identification, validation, and as novel therapeutics.
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A phase I study of EZN-3042, a novel survivin messenger ribonucleic acid (mRNA) antagonist, administered in combination with chemotherapy in children with relapsed acute lymphoblastic leukemia (ALL): a report from the therapeutic advances in childhoDevelopment of a method based on ultra high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry for studying the in vitro metabolism of phosphorothioate oligonucleotides.A phase 1 dose escalation, pharmacokinetic, and pharmacodynamic evaluation of eIF-4E antisense oligonucleotide LY2275796 in patients with advanced cancerFirst-in-human Phase I study of EZN-4176, a locked nucleic acid antisense oligonucleotide to exon 4 of the androgen receptor mRNA in patients with castration-resistant prostate cancer.Novel antisense oligonucleotides containing hydroxamate linkages: targeted iron-triggered chemical nucleases.Therapeutic nucleic acids: current clinical status.Alicaforsen: An Emerging Therapeutic Agent for Ulcerative Colitis and Refractory Pouchitis.Antisense oligonucleotides in neurological disorders.A Dominant Negative Antisense Approach Targeting β-Catenin.
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Advances in antisense oligonucleotide development for target identification, validation, and as novel therapeutics.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 22 September 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Advances in antisense oligonuc ...... on, and as novel therapeutics.
@en
Advances in antisense oligonuc ...... on, and as novel therapeutics.
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type
label
Advances in antisense oligonuc ...... on, and as novel therapeutics.
@en
Advances in antisense oligonuc ...... on, and as novel therapeutics.
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prefLabel
Advances in antisense oligonuc ...... on, and as novel therapeutics.
@en
Advances in antisense oligonuc ...... on, and as novel therapeutics.
@nl
P2860
P356
P1476
Advances in antisense oligonuc ...... ion, and as novel therapeutics
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P2093
Alirio J Melendez
Moizza Mansoor
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P304
P356
10.4137/GRSB.S418
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2008-09-22T00:00:00Z