Tyrosine phosphorylation is required for activation of an alpha interferon-stimulated transcription factor.
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The interferon stimulated gene 54 promotes apoptosisDifferences in interferon alpha and beta signaling. Interferon beta selectively induces the interaction of the alpha and betaL subunits of the type I interferon receptorDirect binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinaseThe type I interferon receptor mediates tyrosine phosphorylation of insulin receptor substrate 2Interaction of the transcriptional activator Stat-2 with the type I interferon receptorAssociation of the interferon-dependent tyrosine kinase Tyk-2 with the hematopoietic cell phosphataseInterferon-alpha engages the insulin receptor substrate-1 to associate with the phosphatidylinositol 3'-kinaseAdenovirus induction of an interferon-regulatory factor during entry into the late phase of infection.Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alphaThe ins and outs of STAT1 nuclear transport.Receptor to nucleus signaling by prolactin and interleukin 2 via activation of latent DNA-binding factors.Inhibition of protein phosphorylation modulates expression of the Jak family protein tyrosine kinasesTracking STAT nuclear traffic.Human cancer cell lines express a negative transcriptional regulator of the interferon regulatory factor family of DNA binding proteins.Disease-activated transcription factor: allergic reactions in human skin cause nuclear translocation of STAT-91 and induce synthesis of keratin K17.Double-stranded RNA activates novel factors that bind to the interferon-stimulated response element.A nuclear tyrosine phosphatase downregulates interferon-induced gene expression.STAT dynamics.Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene.Transmembrane signaling by the alpha subunit of the type I interferon receptor is essential for activation of the JAK kinases and the transcriptional factor ISGF3.A factor induced by differentiation signals in cells of the macrophage lineage binds to the gamma interferon activation site.Go in! Go out! Inducible control of nuclear localization.Tyrosine phosphorylation of measles virus nucleocapsid protein in persistently infected neuroblastoma cells.Enhancement of antiproliferative activity of gamma interferon by the specific inhibition of tyrosine dephosphorylation of Stat1.The regulation of protein transport to the nucleus by phosphorylation.STAT2 nuclear trafficking.Roles of Stat1, Stat2, and interferon regulatory factor-9 (IRF-9) in interferon tau regulation of IRF-1.Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma.Interferon response pathways--a paradigm for cytokine signalling?Requirement of tyrosine- and serine/threonine kinases in the transcriptional activation of the mammalian grp78/BiP promoter by thapsigargin.Revealing the cellular localization of STAT1 during the cell cycle by super-resolution imagingMutant cell lines unresponsive to alpha/beta and gamma interferon are defective in tyrosine phosphorylation of ISGF-3 alpha componentsClass II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes.A negative regulatory region in the intracellular domain of the human interferon-alpha receptor.Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations.Characterization of a Stat-like DNA binding activity in Drosophila melanogaster.
P2860
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P2860
Tyrosine phosphorylation is required for activation of an alpha interferon-stimulated transcription factor.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1992
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Tyrosine phosphorylation is re ...... imulated transcription factor.
@en
Tyrosine phosphorylation is re ...... imulated transcription factor.
@nl
type
label
Tyrosine phosphorylation is re ...... imulated transcription factor.
@en
Tyrosine phosphorylation is re ...... imulated transcription factor.
@nl
prefLabel
Tyrosine phosphorylation is re ...... imulated transcription factor.
@en
Tyrosine phosphorylation is re ...... imulated transcription factor.
@nl
P2093
P2860
P356
P1476
Tyrosine phosphorylation is re ...... imulated transcription factor.
@en
P2093
P2860
P304
11411-11415
P356
10.1073/PNAS.89.23.11411
P407
P577
1992-12-01T00:00:00Z