CCR2 mediates conventional dendritic cell recruitment and the formation of bronchovascular mononuclear cell infiltrates in the lungs of mice infected with Cryptococcus neoformans.
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Cryptococcus and Phagocytes: Complex Interactions that Influence Disease OutcomeDancing cheek to cheek: Cryptococcus neoformans and phagocytesRole of G protein-coupled receptors in control of dendritic cell migrationInflammatory monocytes and the pathogenesis of viral encephalitisMolecular control of monocyte developmentAdaptive immunity to fungiImmunoregulation in Fungal DiseasesEfficacy of β-Lactam-plus-Macrolide Combination Therapy in a Mouse Model of Lethal Pneumococcal PneumoniaInsights into the mechanisms of protective immunity against Cryptococcus neoformans infection using a mouse model of pulmonary cryptococcosisLung dendritic cell expression of maturation molecules increases with worsening chronic obstructive pulmonary disease.Scavenger receptor A modulates the immune response to pulmonary Cryptococcus neoformans infection.Accumulation of CD11b+ lung dendritic cells in response to fungal infection results from the CCR2-mediated recruitment and differentiation of Ly-6Chigh monocytes.Antigen-presenting dendritic cells rescue CD4-depleted CCR2-/- mice from lethal Histoplasma capsulatum infection.TLR9 signaling is required for generation of the adaptive immune protection in Cryptococcus neoformans-infected lungs.Monocyte trafficking to hepatic sites of bacterial infection is chemokine independent and directed by focal intercellular adhesion molecule-1 expressionDual roles of CD40 on microbial containment and the development of immunopathology in response to persistent fungal infection in the lungDistinct CCR2(+) Gr1(+) cells control growth of the Yersinia pestis ΔyopM mutant in liver and spleen during systemic plague.Chemokine receptor 2-mediated accumulation of fungicidal exudate macrophages in mice that clear cryptococcal lung infection.In vivo mechanisms involved in enhanced protection utilizing an Fc receptor-targeted mucosal vaccine platform in a bacterial vaccine and challenge model.CCR2-dependent dendritic cell accumulation in the central nervous system during early effector experimental autoimmune encephalomyelitis is essential for effector T cell restimulation in situ and disease progressionMononuclear phagocyte-mediated antifungal immunity: the role of chemotactic receptors and ligands.Early induction of CCL7 downstream of TLR9 signaling promotes the development of robust immunity to cryptococcal infection.A macrophage subpopulation recruited by CC chemokine ligand-2 clears apoptotic cells in noninfectious lung injuryChitin elicits CCL2 from airway epithelial cells and induces CCR2-dependent innate allergic inflammation in the lung.The Cnes2 locus on mouse chromosome 17 regulates host defense against cryptococcal infection through pleiotropic effects on host immunityPAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury.Blockade of CCR2 reduces macrophage influx and development of chronic renal damage in murine renovascular hypertension.Implicating exudate macrophages and Ly-6C(high) monocytes in CCR2-dependent lung fibrosis following gene-targeted alveolar injury.Altered immune response differentially enhances susceptibility to Cryptococcus neoformans and Cryptococcus gattii infection in mice expressing the HIV-1 transgene.Cryptococcal urease promotes the accumulation of immature dendritic cells and a non-protective T2 immune response within the lung.Dual role of CCR2 in the constitution and the resolution of liver fibrosis in mice.Role of dendritic cells and alveolar macrophages in regulating early host defense against pulmonary infection with Cryptococcus neoformans.The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity.Cryptococcus gattii isolates from the British Columbia cryptococcosis outbreak induce less protective inflammation in a murine model of infection than Cryptococcus neoformans.Chemokine transcripts as targets of the RNA-binding protein HuR in human airway epithelium.Robust Th1 and Th17 immunity supports pulmonary clearance but cannot prevent systemic dissemination of highly virulent Cryptococcus neoformans H99Innate antifungal immunity: the key role of phagocytes.Innate and adaptive antifungal immune responses: partners on an equal footing.Induction of protective immunity against cryptococcosis.Cryptococcus antigens and immune responses: implications for a vaccine.
P2860
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P2860
CCR2 mediates conventional dendritic cell recruitment and the formation of bronchovascular mononuclear cell infiltrates in the lungs of mice infected with Cryptococcus neoformans.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on July 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
CCR2 mediates conventional den ...... with Cryptococcus neoformans.
@en
CCR2 mediates conventional den ...... with Cryptococcus neoformans.
@nl
type
label
CCR2 mediates conventional den ...... with Cryptococcus neoformans.
@en
CCR2 mediates conventional den ...... with Cryptococcus neoformans.
@nl
prefLabel
CCR2 mediates conventional den ...... with Cryptococcus neoformans.
@en
CCR2 mediates conventional den ...... with Cryptococcus neoformans.
@nl
P2093
P2860
P1476
CCR2 mediates conventional den ...... d with Cryptococcus neoformans
@en
P2093
Galen B Toews
Gary B Huffnagle
Gwo-Hsiao Chen
John J Osterholzer
Rod McDonald
Theresa Ames
Timothy Polak
P2860
P304
P356
10.4049/JIMMUNOL.181.1.610
P407
P577
2008-07-01T00:00:00Z