Statin-induced muscle damage and atrogin-1 induction is the result of a geranylgeranylation defect.
about
Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspectiveStatin-Induced Increases in Atrophy Gene Expression Occur Independently of Changes in PGC1α Protein and Mitochondrial ContentStructural analysis of alterations in zebrafish muscle differentiation induced by simvastatin and their recovery with cholesterol.Alterations in zebrafish development induced by simvastatin: Comprehensive morphological and physiological study, focusing on muscle.Farnesyltransferase inhibitor improved survival following endotoxin challenge in mice.Imaging of zebrafish in vivo with second-harmonic generation reveals shortened sarcomeres associated with myopathy induced by statin.Evaluation of skeletal muscle during calf exercise by 31-phosphorus magnetic resonance spectroscopy in patients on statin medications.Mitophagy is required for acute cardioprotection by simvastatin.Mechanisms and assessment of statin-related muscular adverse effects.Intracellular signaling pathways regulating net protein balance following diaphragm muscle denervation.Simvastatin represses protein synthesis in the muscle-derived C₂C₁₂ cell line with a concomitant reduction in eukaryotic initiation factor 2B expressionEffects of lipid-lowering drugs on irisin in human subjects in vivo and in human skeletal muscle cells ex vivo.A small-molecule screening strategy to identify suppressors of statin myopathy.Statins and prostate cancer: role of cholesterol inhibition vs. prevention of small GTP-binding proteinsEndothelial protective genes induced by statin are mimicked by ERK5 activation as triggered by a drug combination of FTI-277 and GGTI-298.A Peculiar Formula of Essential Amino Acids Prevents Rosuvastatin Myopathy in Mice.Proteolysis in illness-associated skeletal muscle atrophy: from pathways to networks.Update on toxic myopathies.In vivo zebrafish assays for analyzing drug toxicity.The role of mitochondria in statin-induced myopathy.Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expression following statin re-challengeSimvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo.Statin myopathy: a lipid clinic experience on the tolerability of statin rechallenge.Simvastatin alters fibroblastic cell responses involved in tissue repair.Geranylgeraniol Prevents Statin-Dependent Myotoxicity in C2C12 Muscle Cells through RAP1 GTPase Prenylation and Cytoprotective Autophagy.Survey of muscle characteristics after statin-induced rhabdomyolysisPharmacogenetics of Adverse Drug Reactions
P2860
Q24594814-79821BE5-11D8-4B6D-8FC9-63991EB7B076Q27305332-9FA9E693-C35D-4C14-B465-B3C3E924E978Q27335506-320848A6-F08B-4873-9CD4-D32770C067CDQ30823700-D51260E9-873D-4E1A-BED1-C88FB203E0B7Q33620009-EFD8528E-949D-492D-91D6-3AF00FEF0B36Q34037784-BDBF2F70-6FE1-4E83-9BB3-5D53DFE01F85Q34155702-63DA5AAE-0DE4-4EA6-9EE4-662695CC18B1Q34399751-6458AD0A-CCC4-491C-87E9-987B2AD691CDQ34570995-C292A744-0CFA-41CE-BA59-AFD355BF0E0BQ34597522-DAD0832B-E3EA-495F-BA78-BAA90D047557Q34718197-37693239-BEE0-424F-8136-63BA4BC01F68Q34984106-0BB2BEAD-803F-4A37-8EDB-6B644E7736E9Q35223789-592DC4DD-5E16-46D8-A00A-000E6F11B46CQ35264079-1F411F5B-13E8-49E5-A01D-E41832339A17Q35736398-5212332E-451D-48EE-9B9C-57D34B351F9FQ37341027-0DE1FF33-9666-4C2B-9A47-F7C0A2B53BF0Q37893657-E7E06D9A-6BA3-4FBC-9F98-D7B7EC9805EDQ37942033-470A4AFC-EED3-403D-9EB6-BDF396176C8EQ38195070-AE812565-9BB3-4D9D-8AE6-D1E8CF341F5BQ38492567-423C4F6E-9589-46A3-9EA9-22846C6AF338Q38644316-33F344A8-8E7A-4BCA-91E3-D8FAB3AF7025Q38949342-17B9F3D0-0DEF-4FD5-9FD8-1EC3B040DCDCQ39711727-40D9DE7D-C116-46B4-B9DD-6BBF48BC7B09Q43699737-5C27220B-DABF-4C1A-B3C3-9E01100BF7BDQ55287021-6667A9E8-3D1F-4984-8F24-C5EA517EE050Q57012223-9311B0F2-C7E6-47B8-9BA3-8C9C8B9DF6A2Q57302676-9CB3A8C2-D401-4FEA-B97B-5C031923F650
P2860
Statin-induced muscle damage and atrogin-1 induction is the result of a geranylgeranylation defect.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 30 April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Statin-induced muscle damage a ...... a geranylgeranylation defect.
@en
Statin-induced muscle damage a ...... a geranylgeranylation defect.
@nl
type
label
Statin-induced muscle damage a ...... a geranylgeranylation defect.
@en
Statin-induced muscle damage a ...... a geranylgeranylation defect.
@nl
prefLabel
Statin-induced muscle damage a ...... a geranylgeranylation defect.
@en
Statin-induced muscle damage a ...... a geranylgeranylation defect.
@nl
P2093
P2860
P356
P1433
P1476
Statin-induced muscle damage a ...... a geranylgeranylation defect.
@en
P2093
Jun-Ichi Hanai
Peirang Cao
Preeti Tanksale
Shintaro Imamura
Stewart H Lecker
Vikas P Sukhatme
P2860
P304
P356
10.1096/FJ.08-128843
P407
P577
2009-04-30T00:00:00Z