GABA(B) receptor activation inhibits neuronal excitability and spatial learning in the entorhinal cortex by activating TREK-2 K+ channels.
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Intrinsic electrophysiological properties of entorhinal cortex stellate cells and their contribution to grid cell firing fieldsCross-talk and regulation between glutamate and GABAB receptorsTwo-pore Domain Potassium Channels in AstrocytesCholecystokinin facilitates glutamate release by increasing the number of readily releasable vesicles and releasing probability.Neurotensinergic Excitation of Dentate Gyrus Granule Cells via Gαq-Coupled Inhibition of TASK-3 Channels.Corticotropin-releasing factor facilitates epileptiform activity in the entorhinal cortex: roles of CRF2 receptors and PKA pathway.Effects of GABAB receptors in the insula on recognition memory observed with intellicageActivation of neurotensin receptor 1 facilitates neuronal excitability and spatial learning and memory in the entorhinal cortex: beneficial actions in an Alzheimer's disease modelThe involvement of potassium channel ORK1 in short-term memory and sleep in Drosophila.DNA methylation signatures in cord blood associated with maternal gestational weight gain: results from the ALSPAC cohortAdenosinergic depression of glutamatergic transmission in the entorhinal cortex of juvenile rats via reduction of glutamate release probability and the number of releasable vesiclesGABAB receptor modulation of voltage-sensitive calcium channels in spines and dendrites.Correlation of cognitive performance and morphological changes in neocortical pyramidal neurons in agingTarget-selective GABAergic control of entorhinal cortex outputCholecystokinin facilitates neuronal excitability in the entorhinal cortex via activation of TRPC-like channels.Molecular regulations governing TREK and TRAAK channel functions.Requirement of phospholipase C and protein kinase C in cholecystokinin-mediated facilitation of NMDA channel function and anxiety-like behavior.Multivariate analysis of subjective responses to d-amphetamine in healthy volunteers finds novel genetic pathway associationsOptical control of endogenous proteins with a photoswitchable conditional subunit reveals a role for TREK1 in GABA(B) signaling.Phospholipase C not protein kinase C is required for the activation of TRPC5 channels by cholecystokininBehavioral characterization of mice lacking Trek channels.Vasopressin facilitates GABAergic transmission in rat hippocampus via activation of V(1A) receptors.Activation of group II metabotropic glutamate receptors inhibits glutamatergic transmission in the rat entorhinal cortex via reduction of glutamate release probability.The association of DNA methylation and brain volume in healthy individuals and schizophrenia patientsAllosteric coupling between proximal C-terminus and selectivity filter is facilitated by the movement of transmembrane segment 4 in TREK-2 channel.A role for TREK1 in generating the slow afterhyperpolarization in developing starburst amacrine cells.Intersubunit Concerted Cooperative and cis-Type Mechanisms Modulate Allosteric Gating in Two-Pore-Domain Potassium Channel TREK-2.Target-selectivity of parvalbumin-positive interneurons in layer II of medial entorhinal cortex in normal and epileptic animalsGABAB receptor modulation of synaptic function.Expression and localisation of two-pore domain (K2P) background leak potassium ion channels in the mouse retina.Identification and characterization of alternative splice variants of the mouse Trek2/Kcnk10 gene.Towards therapeutic applications of arthropod venom k(+)-channel blockers in CNS neurologic diseases involving memory acquisition and storage.Repeated cocaine weakens GABA(B)-Girk signaling in layer 5/6 pyramidal neurons in the prelimbic cortex.KCNK10, a tandem pore domain potassium channel, is a regulator of mitotic clonal expansion during the early stage of adipocyte differentiation.Inhibition of dendritic Ca2+ spikes by GABAB receptors in cortical pyramidal neurons is mediated by a direct Gi/o-β-subunit interaction with Cav1 channels.Activation of TREK-1 by morphine results in analgesia without adverse side effects.Adenosine modulates the excitability of layer II stellate neurons in entorhinal cortex through A1 receptors.GABAB receptors in neocortical and hippocampal pyramidal neurons are coupled to different potassium channels.Superficial Layer-Specific Histaminergic Modulation of Medial Entorhinal Cortex Required for Spatial Learning.Histamine facilitates GABAergic transmission in the rat entorhinal cortex: Roles of H1 and H2 receptors, Na+ -permeable cation channels, and inward rectifier K+ channels.
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P2860
GABA(B) receptor activation inhibits neuronal excitability and spatial learning in the entorhinal cortex by activating TREK-2 K+ channels.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2009
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
GABA(B) receptor activation in ...... activating TREK-2 K+ channels.
@en
type
label
GABA(B) receptor activation in ...... activating TREK-2 K+ channels.
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prefLabel
GABA(B) receptor activation in ...... activating TREK-2 K+ channels.
@en
P2093
P2860
P1433
P1476
GABA(B) receptor activation in ...... activating TREK-2 K+ channels.
@en
P2093
Chuanxiu Yang
James E Porter
Jonathan D Geiger
Lalida Rojanathammanee
Laurel Grisanti
Pan-Yue Deng
Zhaoyang Xiao
P2860
P304
P356
10.1016/J.NEURON.2009.06.022
P407
P577
2009-07-01T00:00:00Z