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In vivo bioluminescent imaging (BLI): noninvasive visualization and interrogation of biological processes in living animalsAge-dependent neuroinflammation and cognitive decline in a novel Ala152Thr-Tau transgenic mouse model of PSP and AD.Non-invasive quantification of brain tumor-induced astrogliosis.Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein.Biology and genetics of prions causing neurodegenerationMouse models for studying the formation and propagation of prions.The emerging use of in vivo optical imaging in the study of neurodegenerative diseases.An aggregation sensing reporter identifies leflunomide and teriflunomide as polyglutamine aggregate inhibitors.Successes and challenges in phenotype-based lead discovery for prion diseasesConformation-dependent high-affinity monoclonal antibodies to prion proteins.Finding degrees of separation: experimental approaches for astroglial and oligodendroglial cell isolation and genetic targetingPrions.Bioluminescence imaging of Abeta deposition in bigenic mouse models of Alzheimer's disease.Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease.Intravital Fluorescence Excitation in Whole-Animal Optical ImagingIntracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice.Purified and synthetic Alzheimer's amyloid beta (Aβ) prions.Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein.Plasma membrane invaginations containing clusters of full-length PrPSc are an early form of prion-associated neuropathology in vivo.GFAP expression as an indicator of disease severity in mouse models of Alexander disease.Systemic immune activation leads to neuroinflammation and sickness behavior in mice.Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice.Drug resistance confounding prion therapeutics.Guinea Pig Prion Protein Supports Rapid Propagation of Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease Prions.Transmission of multiple system atrophy prions to transgenic miceBioluminescent imaging of drug efflux at the blood-brain barrier mediated by the transporter ABCG2Bioluminescence imaging: progress and applicationsMaking the brain glow: in vivo bioluminescence imaging to study neurodegeneration.Bioassays and Inactivation of Prions.Developing Therapeutics for PrP Prion Diseases.Cell biology. A unifying role for prions in neurodegenerative diseases.Driving drug discovery: the fundamental role of academic labs.Bioluminescence Imaging of Neuroinflammation in Transgenic Mice After Peripheral Inoculation of Alpha-Synuclein Fibrils.Imaging of Glial Activation in Alzheimer's Disease
P2860
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P2860
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 17 August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Measuring prions by bioluminescence imaging.
@en
Measuring prions by bioluminescence imaging.
@nl
type
label
Measuring prions by bioluminescence imaging.
@en
Measuring prions by bioluminescence imaging.
@nl
prefLabel
Measuring prions by bioluminescence imaging.
@en
Measuring prions by bioluminescence imaging.
@nl
P2093
P2860
P50
P356
P1476
Measuring prions by bioluminescence imaging.
@en
P2093
Azucena Lemus
Gültekin Tamgüney
Kevin P Francis
P2860
P304
15002-15006
P356
10.1073/PNAS.0907339106
P407
P577
2009-08-17T00:00:00Z