Inhibition of BET bromodomain-dependent XIAP and FLIP expression sensitizes KRAS-mutated NSCLC to pro-apoptotic agents
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Super-enhancers define a proliferative PGC-1α-expressing melanoma subgroup sensitive to BET inhibition.BET inhibition is an effective approach against KRAS-driven PDAC and NSCLC.JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states
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Inhibition of BET bromodomain-dependent XIAP and FLIP expression sensitizes KRAS-mutated NSCLC to pro-apoptotic agents
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 September 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Inhibition of BET bromodomain- ...... NSCLC to pro-apoptotic agents
@en
Inhibition of BET bromodomain- ...... NSCLC to pro-apoptotic agents.
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type
label
Inhibition of BET bromodomain- ...... NSCLC to pro-apoptotic agents
@en
Inhibition of BET bromodomain- ...... NSCLC to pro-apoptotic agents.
@nl
prefLabel
Inhibition of BET bromodomain- ...... NSCLC to pro-apoptotic agents
@en
Inhibition of BET bromodomain- ...... NSCLC to pro-apoptotic agents.
@nl
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Inhibition of BET bromodomain- ...... NSCLC to pro-apoptotic agents
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Bernard Haendler
Kathy A Gelato
Pascale Lejeune
Ralf Lesche
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P2888
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10.1038/CDDIS.2016.271
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P577
2016-09-08T00:00:00Z
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1033609711