Ovarian cancer cell detachment and multicellular aggregate formation are regulated by membrane type 1 matrix metalloproteinase: a potential role in I.p. metastatic dissemination.
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Fibronectin assembly in the crypts of cytokinesis-blocked multilobular cells promotes anchorage-independent growthThe mechanics of metastasis: insights from a computational modelIdentification of ovarian cancer metastatic miRNAsβ-Catenin-regulated ALDH1A1 is a target in ovarian cancer spheroidsGene expression in the efferent ducts, epididymis, and vas deferens during embryonic development of the mouse.Decreased levels of baseline and drug-induced tubulin polymerisation are hallmarks of resistance to taxanes in ovarian cancer cells and are associated with epithelial-to-mesenchymal transitionOvarian cancer development and metastasis.Rho-ROCK-myosin signaling mediates membrane type 1 matrix metalloproteinase-induced cellular aggregation of keratinocytes.Overexpression of proto-oncogene FBI-1 activates membrane type 1-matrix metalloproteinase in association with adverse outcome in ovarian cancersMultivalent epigenetic marks confer microenvironment-responsive epigenetic plasticity to ovarian cancer cells.Expression profiling of primary and metastatic ovarian tumors reveals differences indicative of aggressive disease.The role of multicellular aggregation in the survival of ErbB2-positive breast cancer cells during extracellular matrix detachmentIn vivo optical imaging of membrane-type matrix metalloproteinase (MT-MMP) activityA method to investigate the anti-metabolic activity of anti-cancer agents on ovarian cancer cells cultured in a 96-well high throughput formatMembrane type 1 matrix metalloproteinase (MT1-MMP) ubiquitination at Lys581 increases cellular invasion through type I collagen.Hydrogel Microwell Arrays Allow the Assessment of Protease-Associated Enhancement of Cancer Cell Aggregation and Survival.Matrix rigidity activates Wnt signaling through down-regulation of Dickkopf-1 proteinExpression of MMP-2, -7, -9, MT1-MMP and TIMP-1 and -2 has no prognostic relevance in patients with advanced epithelial ovarian cancer.Intraoperative imaging in ovarian cancer: fact or fiction?Integrin-linked kinase activity modulates the pro-metastatic behavior of ovarian cancer cells.EGF-receptor regulation of matrix metalloproteinases in epithelial ovarian carcinoma.Metastasis of ovarian cancer is mediated by kallikrein related peptidases.Selective blockade of matrix metalloprotease-14 with a monoclonal antibody abrogates invasion, angiogenesis, and tumor growth in ovarian cancer.Epithelial ovarian cancer experimental models.Ovarian cancer molecular pathology.Cadherin composition and multicellular aggregate invasion in organotypic models of epithelial ovarian cancer intraperitoneal metastasis.Post-translational modification of the membrane type 1 matrix metalloproteinase (MT1-MMP) cytoplasmic tail impacts ovarian cancer multicellular aggregate dynamics.Kallikrein-related peptidases (KLKs) and the hallmarks of cancer.Membrane-type I matrix metalloproteinase-dependent ectodomain shedding of mucin16/ CA-125 on ovarian cancer cells modulates adhesion and invasion of peritoneal mesothelium.Modulation of AKT activity is associated with reversible dormancy in ascites-derived epithelial ovarian cancer spheroids.Phosphorylation of membrane type 1-matrix metalloproteinase (MT1-MMP) and its vesicle-associated membrane protein 7 (VAMP7)-dependent trafficking facilitate cell invasion and migration.Visual and automated assessment of matrix metalloproteinase-14 tissue expression for the evaluation of ovarian cancer prognosis.Manipulating magnetic 3D spheroids in hanging drops for applications in tissue engineering and drug screening.Fibroblasts in omentum activated by tumor cells promote ovarian cancer growth, adhesion and invasiveness.The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation.
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P2860
Ovarian cancer cell detachment and multicellular aggregate formation are regulated by membrane type 1 matrix metalloproteinase: a potential role in I.p. metastatic dissemination.
description
article científic
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article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 25 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Ovarian cancer cell detachment ...... I.p. metastatic dissemination.
@en
Ovarian cancer cell detachment ...... I.p. metastatic dissemination.
@nl
type
label
Ovarian cancer cell detachment ...... I.p. metastatic dissemination.
@en
Ovarian cancer cell detachment ...... I.p. metastatic dissemination.
@nl
prefLabel
Ovarian cancer cell detachment ...... I.p. metastatic dissemination.
@en
Ovarian cancer cell detachment ...... I.p. metastatic dissemination.
@nl
P2093
P2860
P1433
P1476
Ovarian cancer cell detachment ...... I.p. metastatic dissemination.
@en
P2093
Hidayatullah G Munshi
M Sharon Stack
Maria V Barbolina
Natalie M Moss
Yueying Liu
P2860
P304
P356
10.1158/0008-5472.CAN-08-4151
P407
P577
2009-08-25T00:00:00Z