Mechanism for discrimination between viral and host mRNA in interferon-treated cells.
about
A dominant negative mutant of 2-5A-dependent RNase suppresses antiproliferative and antiviral effects of interferonInterferon-induced 56,000 Mr protein and its mRNA in human cells: molecular cloning and partial sequence of the cDNADiverse functions of RNase L and implications in pathologyA scientific journey through the 2-5A/RNase L systemViral encounters with 2',5'-oligoadenylate synthetase and RNase L during the interferon antiviral responseRNase L restricts the mobility of engineered retrotransposons in cultured human cellsRNase L mediates the antiviral effect of interferon through a selective reduction in viral RNA during encephalomyocarditis virus infectionRNase-L-dependent destabilization of interferon-induced mRNAs. A role for the 2-5A system in attenuation of the interferon response.Interferon, double-stranded RNA, and RNA degradation: activation of an endonuclease by (2'-5')AnAdvances in interferon research - Medical Staff Conference.Murine AKAP7 has a 2',5'-phosphodiesterase domain that can complement an inactive murine coronavirus ns2 gene.Structural requirements of (2'-5') oligoadenylate for protein synthesis inhibition in human fibroblastsNucleoside modifications in RNA limit activation of 2'-5'-oligoadenylate synthetase and increase resistance to cleavage by RNase LActivation of interferon-regulated, dsRNA-dependent enzymes by human immunodeficiency virus-1 leader RNA.Characterization of the products of the U(L)43 gene of herpes simplex virus 1: potential implications for regulation of gene expression by antisense transcriptionPathologic effects of RNase-L dysregulation in immunity and proliferative control.Regulation of the stability of poly(I)xpoly(C)-induced human fibroblast interferon mRNA: selective inactivation of interferon mRNA and lack of involvement of 2',5'-oligo(A) synthetase activation during the shutoff of interferon productionInterferon action: binding of viral RNA to the 40-kilodalton 2'-5'-oligoadenylate synthetase in interferon-treated HeLa cells infected with encephalomyocarditis virus.Specific effect of interferon on the herpes simplex virus type 1 transactivation event.Studies on the role of the 2'-5'-oligoadenylate synthetase-RNase L pathway in beta interferon-mediated inhibition of encephalomyocarditis virus replication.Cleavage of nascent reovirus mRNA by localized activation of the 2'-5'-oligoadenylate-dependent endoribonuclease.Inhibition of binding to initiation complexes of nascent reovirus mRNA by double-stranded RNA-dependent protein kinase.Double-stranded RNA-dependent protein kinase and 2-5A system are both activated in interferon-treated, encephalomyocarditis virus-infected HeLa cells.Inhibition of viral mRNA translation in interferon-treated L cells infected with reovirusSynthesis of (2'-5')oligoadenylate and activation of an endoribonuclease in interferon-treated HeLa cells infected with reovirusInduction and maintenance of 2',5'-oligoadenylate synthetase in interferon-treated chicken embryo cells.An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity.Ribosomal protein mRNAs are primary targets of regulation in RNase-L-induced senescence.Possible involvement of (2'5')oligoadenylate synthetase activity in pre-mRNA splicing.RNase-L control of cellular mRNAs: roles in biologic functions and mechanisms of substrate targeting.Molecular sub-group-specific immunophenotypic changes are associated with outcome in recurrent posterior fossa ependymomaRegulation of cell proliferation and differentiation by interferons.Differential effect of murine alpha/beta interferon transgenes on antagonization of herpes simplex virus type 1 replication.The interferon renaissance: molecular aspects of induction and action.Heterogeneous nuclear RNA promotes synthesis of (2',5')oligoadenylate and is cleaved by the (2',5')oligoadenylate-activated endoribonuclease.Interferon-induced enzymes: activation and role in te antiviral state.Role of interferon-induced enzymes in the antiviral and antimitogenic effects of interferon.Antiviral activity of a chemically stabilized 2-5A analog upon microinjection into HeLa cells.
P2860
Q24564476-9DB2C2D1-3127-4CA4-82BC-DE11960A0D8AQ24609939-93CA0B63-E195-4B0A-BC80-C76CE9C4524CQ24652347-7A82F61D-CF20-4F18-9728-C7EF9237D977Q24679551-8593B9F7-0E9A-4C5E-8652-0E2DC8E2A903Q24681387-9DD5FA70-6753-4BB0-A380-8A27E99052C9Q28660459-A0226C17-0AC1-4C9F-AEBC-DE70DD7956A1Q33783019-E417E5D0-5680-4145-A2F5-9F812504BD85Q33893743-69EB97C9-9A4D-422D-8C10-D15DD1EB4D21Q34033515-1233C746-3AE5-4D0F-AF61-CA9FF31BA2FBQ34111204-357A31C0-9FFD-48D6-85D4-149B20AAB68BQ34165352-2E0C7336-C685-4433-9D13-BF37F8F245F3Q35499059-AE6E493B-1F65-45B3-BE44-C59A4277E360Q35620847-4088C62C-4929-41F1-BB4B-D6E1616D4F54Q35864756-6898C7F8-A9B3-4FD0-B8DF-D67213E93E45Q35871964-E6DED7B0-73B8-4B63-870A-DAE27584BD11Q36310770-0E260BEE-B0E8-4A97-A00E-149D7D562BD1Q36394019-2562E5D2-974E-43CC-A5FE-2D234840FE1DQ36683577-F02E5188-0598-4CF9-B555-8ED892536D00Q36806771-94930590-B06A-4687-9586-8F0AB021458EQ36872268-BB62FEAA-CBAB-47BE-8679-C938703651A0Q36896656-2446D836-EF3B-45E2-B12D-2CB0A156CDB0Q36901170-E47EC6ED-7CAA-4FE2-8E11-FE617799AFD3Q36902455-13A580BF-2AD0-45B0-A51F-E1DF2F7BF21BQ36904220-5727B290-2893-4E33-A60B-F710A4BC8AABQ36941486-42AB4B4B-25C3-412F-834A-CEBA6CFCF594Q36976317-EDB95E6E-366B-43BC-AB59-8026CA72139DQ37081654-501ED3EA-818F-4897-8957-6529735057F1Q37363922-7DA335D3-242A-4648-AA72-CA4ED1726A79Q37626238-0FE7759F-5DC3-4D22-974B-54D5F97D4604Q37686220-21397BF4-87CD-4AEA-B956-D778F4819E37Q37705192-0CBBCA69-F9EC-4145-9618-63A002CA0B9FQ38393349-2E08E6BD-1859-4CEA-8D86-BA6F53FA6918Q39683981-2C053182-34E2-4B4E-AAE3-A84D3D5CD2A4Q40100981-CDB6DD7D-6E16-4813-B339-CFC39A52E0DAQ40679207-F2F868BF-CCFA-4DEB-AF62-F9D9B2B48B21Q43617358-DB20DF91-1A01-4507-8C9F-C79C8D78AD85Q43973440-90B87CC4-BA7A-446B-AAD8-0CCD4BAAB3BEQ54430993-95C9D9B5-0763-4C0F-BDBA-E06A05360F13
P2860
Mechanism for discrimination between viral and host mRNA in interferon-treated cells.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 1979
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mechanism for discrimination between viral and host mRNA in interferon-treated cells.
@en
Mechanism for discrimination between viral and host mRNA in interferon-treated cells.
@nl
type
label
Mechanism for discrimination between viral and host mRNA in interferon-treated cells.
@en
Mechanism for discrimination between viral and host mRNA in interferon-treated cells.
@nl
prefLabel
Mechanism for discrimination between viral and host mRNA in interferon-treated cells.
@en
Mechanism for discrimination between viral and host mRNA in interferon-treated cells.
@nl
P2860
P356
P1476
Mechanism for discrimination between viral and host mRNA in interferon-treated cells.
@en
P2093
P2860
P304
P356
10.1073/PNAS.76.6.2600
P407
P577
1979-06-01T00:00:00Z