Pharmacokinetic analysis of trichloroethylene metabolism in male B6C3F1 mice: Formation and disposition of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine.
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The trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine but not trichloroacetate inhibits pathogen-stimulated TNF-α in human extraplacental membranes in vitroPhysiologically based pharmacokinetic (PBPK) modeling of interstrain variability in trichloroethylene metabolism in the mouse.Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred miceTrichloroethylene biotransformation and its role in mutagenicity, carcinogenicity and target organ toxicity.Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: liver effects.Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects.The Contribution of Peroxisome Proliferator-Activated Receptor Alpha to the Relationship Between Toxicokinetics and Toxicodynamics of Trichloroethylene.Occupational health risks among trichloroethylene-exposed workers in a clock manufacturing factory.Trichloroethylene: Mechanistic, epidemiologic and other supporting evidence of carcinogenic hazard.Three common pathways of nephrotoxicity induced by halogenated alkenes.A new bacterial biosensor for trichloroethylene detection based on a three-dimensional carbon nanotubes bioarchitecture.Editor's Highlight: Collaborative Cross Mouse Population Enables Refinements to Characterization of the Variability in Toxicokinetics of Trichloroethylene and Provides Genetic Evidence for the Role of PPAR Pathway in Its Oxidative Metabolism.Editor's Highlight: Comparative Dose-Response Analysis of Liver and Kidney Transcriptomic Effects of Trichloroethylene and Tetrachloroethylene in B6C3F1 Mouse.Editor's Highlight: High-Throughput Functional Genomics Identifies Modulators of TCE Metabolite Genotoxicity and Candidate Susceptibility Genes.Characterization of inter-tissue and inter-strain variability of TCE glutathione conjugation metabolites DCVG, DCVC, and NAcDCVC in the mouse.Carbon Nanotube Based Groundwater Remediation: The Case of Trichloroethylene.[Health evaluation of trichloroethylene in indoor air : communication from the German ad-hoc working group on indoor guidelines of the Indoor Air Hygiene Committee and of the states' supreme health authorities].
P2860
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P2860
Pharmacokinetic analysis of trichloroethylene metabolism in male B6C3F1 mice: Formation and disposition of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine.
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article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 03 May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Pharmacokinetic analysis of tr ...... 1,2-dichlorovinyl)-L-cysteine.
@en
Pharmacokinetic analysis of tr ...... 1,2-dichlorovinyl)-L-cysteine.
@nl
type
label
Pharmacokinetic analysis of tr ...... 1,2-dichlorovinyl)-L-cysteine.
@en
Pharmacokinetic analysis of tr ...... 1,2-dichlorovinyl)-L-cysteine.
@nl
prefLabel
Pharmacokinetic analysis of tr ...... 1,2-dichlorovinyl)-L-cysteine.
@en
Pharmacokinetic analysis of tr ...... 1,2-dichlorovinyl)-L-cysteine.
@nl
P2093
P2860
P1476
Pharmacokinetic analysis of tr ...... 1,2-dichlorovinyl)-L-cysteine.
@en
P2093
Gary M Pollack
Ivan Rusyn
Leonard B Collins
Sungkyoon Kim
P2860
P356
10.1016/J.TAAP.2009.04.019
P577
2009-05-03T00:00:00Z