Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease. - Wikidata - wikimedia - TriplyDB

Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease.

Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease.

http://www.wikidata.org/entity/Q37334961

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Mitochondria-Targeted Protective Compounds in Parkinson's and Alzheimer's Diseases Novel mitochondrial targets for neuroprotection Multi-target drugs: the trend of drug research and development Acetyl L-carnitine protects motor neurons and Rohon-Beard sensory neurons against ketamine-induced neurotoxicity in zebrafish embryos.Acetyl-L-carnitine ameliorates mitochondrial dysfunction following contusion spinal cord injury.Lipoamide Acts as an Indirect Antioxidant by Simultaneously Stimulating Mitochondrial Biogenesis and Phase II Antioxidant Enzyme Systems in ARPE-19 Cells.Chemical screen reveals small molecules suppressing fragile X premutation rCGG repeat-mediated neurodegeneration in Drosophila.Recent advances on the neuroprotective potential of antioxidants in experimental models of Parkinson's disease.Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases.Endogenous neuroprotection in chronic neurodegenerative disorders: with particular regard to the kynurenines.The contributions of antioxidant activity of lipoic acid in reducing neurogenerative progression of Parkinson's disease: a review.Pharmacological effects and clinical applications of propionyl-L-carnitine.Mitochondrial complex I inhibitor rotenone-induced toxicity and its potential mechanisms in Parkinson's disease models.Mitochondrial dysfunction in psychiatric and neurological diseases: cause(s), consequence(s), and implications of antioxidant therapy.Preconditioning as a potential strategy for the prevention of Parkinson's disease.Hypoxic preconditioning protects cardiomyocytes against hypoxia/reoxygenation injury through AMPK/eNOS/PGC-1α signaling pathway.α-Lipoic Acid Inhibits Expression of IL-8 by Suppressing Activation of MAPK, Jak/Stat, and NF-κB in H. pylori-Infected Gastric Epithelial AGS Cells.α-Lipoic acid, functional fatty acid, as a novel therapeutic alternative for central nervous system diseases: A review.Potential Therapeutic Effects of Lipoic Acid on Memory Deficits Related to Aging and Neurodegeneration.ALCAR Exerts Neuroprotective and Pro-Neurogenic Effects by Inhibition of Glial Activation and Oxidative Stress via Activation of the Wnt/β-Catenin Signaling in Parkinsonian Rats.Mitochondrial nutrients stimulate performance and mitochondrial biogenesis in exhaustively exercised rats.

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Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease.

http://www.wikidata.org/entity/Q37334961

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scientific article published on January 2010

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J.1582-4934.2008.00390.X

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Journal of Cellular and Molecular Medicine

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Combined R-alpha-lipoic acid a ...... r model of Parkinson's disease

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Bing Yan

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Jianghai Liu

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Jiankang Liu

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Ni Ao

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Weili Shen

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Xin Li

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Xuemin Wang

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P2860

Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid

alpha-Lipoic acid as a biological antioxidant.

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies

Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators

Oxidative stress in Parkinson's disease

Parkinson's disease. First of two parts

Bioenergetic approaches for neuroprotection in Parkinson's disease.

Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.

Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid.

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215-225

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10.1111/J.1582-4934.2008.00390.X

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1-2

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2010-01-01T00:00:00Z

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227651184

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20414966

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Parkinson's disease

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3837594

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