Regulator of G-protein signaling 10 promotes dopaminergic neuron survival via regulation of the microglial inflammatory response
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Cellular deficiency in the RGS10 protein facilitates chemoresistant ovarian cancerAmitriptyline-mediated cognitive enhancement in aged 3×Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activityAdolescent binge drinking alters adult brain neurotransmitter gene expression, behavior, brain regional volumes, and neurochemistry in mice.Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic interventionExpression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysisLipopolysaccharide and tumor necrosis factor regulate Parkin expression via nuclear factor-kappa B.Networks of neuronal genes affected by common and rare variants in autism spectrum disorders.Critical role of regulator G-protein signaling 10 (RGS10) in modulating macrophage M1/M2 activation.Discovery of binding proteins for a protein target using protein-protein docking-based virtual screening.Age-related changes in regulator of G-protein signaling (RGS)-10 expression in peripheral and central immune cells may influence the risk for age-related degeneration.Strategies for study of neuroprotection from cold-preconditioningPsychological stress in adolescent and adult mice increases neuroinflammation and attenuates the response to LPS challenge.Regulator of G-protein signaling-10 negatively regulates NF-κB in microglia and neuroprotects dopaminergic neurons in hemiparkinsonian rats.RGS10 Negatively Regulates Platelet Activation and Thrombogenesis.RGS10 exerts a neuroprotective role through the PKA/c-AMP response-element (CREB) pathway in dopaminergic neuron-like cells.Relevance of PTEN loss in brain metastasis formation in breast cancer patientsCeramide sphingolipid signaling mediates Tumor Necrosis Factor (TNF)-dependent toxicity via caspase signaling in dopaminergic neurons.Modulating platelet reactivity through control of RGS18 availability.Progranulin does not bind tumor necrosis factor (TNF) receptors and is not a direct regulator of TNF-dependent signaling or bioactivity in immune or neuronal cells.Neuroinflammation in Parkinson's disease.Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease.Microglial activation and chronic neurodegeneration.Control of striatal signaling by g protein regulators.Neuroimmune basis of alcoholic brain damage.Regulator of G Protein Signaling 10 (Rgs10) Expression Is Transcriptionally Silenced in Activated Microglia by Histone Deacetylase Activity.Regulator of G-protein Signaling (RGS)1 and RGS10 Proteins as Potential Drug Targets for Neuroinflammatory and Neurodegenerative Diseases.The impact of RGS and other G-protein regulatory proteins on Gαi-mediated signaling in immunity.Microglial phenotypes in Parkinson's disease and animal models of the disease.Caveolin isoform switching as a molecular, structural, and metabolic regulator of microglia.Regulation of microglia effector functions by tumor necrosis factor signaling.RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis.The gamma chain subunit of Fc receptors is required for alpha-synuclein-induced pro-inflammatory signaling in microglia.Generation of single-cell suspensions from mouse neural tissue.Isolation of murine postnatal brain microglia for phenotypic characterization using magnetic cell separation technologyRegulating the regulators: Epigenetic, transcriptional, and post-translational regulation of RGS proteins.TNF-α Mediates the Intrinsic and Extrinsic Pathway in Propofol-Induced Neuronal Apoptosis Via PI3K/Akt Signaling Pathway in Rat Prefrontal Cortical Neurons.Genetic Analysis of Rare Human Variants of Regulators of G Protein Signaling Proteins and Their Role in Human Physiology and DiseaseIFN-γ Producing Th1 Cells Induce Different Transcriptional Profiles in Microglia and AstrocytesRGS10 shapes the hemostatic response to injury through its differential effects on intracellular signaling by platelet agonists
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Regulator of G-protein signaling 10 promotes dopaminergic neuron survival via regulation of the microglial inflammatory response
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 2008
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Regulator of G-protein signali ...... croglial inflammatory response
@en
Regulator of G-protein signali ...... roglial inflammatory response.
@nl
type
label
Regulator of G-protein signali ...... croglial inflammatory response
@en
Regulator of G-protein signali ...... roglial inflammatory response.
@nl
prefLabel
Regulator of G-protein signali ...... croglial inflammatory response
@en
Regulator of G-protein signali ...... roglial inflammatory response.
@nl
P2093
P2860
P921
P1476
Regulator of G-protein signali ...... croglial inflammatory response
@en
P2093
Ashley S Harms
Kelly A Ruhn
Melissa K McCoy
Stephen J Gold
P2860
P304
P356
10.1523/JNEUROSCI.1806-08.2008
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P577
2008-08-01T00:00:00Z