Activation of the liver X receptor stimulates trans-intestinal excretion of plasma cholesterol. - Wikidata - wikimedia - TriplyDB

Activation of the liver X receptor stimulates trans-intestinal excretion of plasma cholesterol.

Activation of the liver X receptor stimulates trans-intestinal excretion of plasma cholesterol.

http://www.wikidata.org/entity/Q37339259

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A new model of reverse cholesterol transport: enTICEing strategies to stimulate intestinal cholesterol excretion From evolution to revolution: miRNAs as pharmacological targets for modulating cholesterol efflux and reverse cholesterol transport Hepatic farnesoid X-receptor isoforms α2 and α4 differentially modulate bile salt and lipoprotein metabolism in mice A new framework for reverse cholesterol transport: non-biliary contributions to reverse cholesterol transport.Dynamics of hepatic and intestinal cholesterol and bile acid pathways: The impact of the animal model of estrogen deficiency and exercise training Liver X receptors at the intersection of lipid metabolism and atherogenesis Role of the intestinal bile acid transporters in bile acid and drug disposition A reappraisal of the mechanism by which plant sterols promote neutral sterol loss in mice Liver LXRα expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice Coordinated Actions of FXR and LXR in Metabolism: From Pathogenesis to Pharmacological Targets for Type 2 Diabetes Acute sterol o-acyltransferase 2 (SOAT2) knockdown rapidly mobilizes hepatic cholesterol for fecal excretion.Acceleration of biliary cholesterol secretion restores glycemic control and alleviates hypertriglyceridemia in obese db/db mice.Biliary sterol secretion is not required for macrophage reverse cholesterol transport Cooperative transcriptional activation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 genes by nuclear receptors including Liver-X-Receptor.C57Bl/6 N mice on a western diet display reduced intestinal and hepatic cholesterol levels despite a plasma hypercholesterolemia Cell cholesterol homeostasis: mediation by active cholesterol PCSK9 and LDLR degradation: regulatory mechanisms in circulation and in cells.Statins increase hepatic cholesterol synthesis and stimulate fecal cholesterol elimination in mice.Relative roles of ABCG5/ABCG8 in liver and intestine.The combination of ezetimibe and ursodiol promotes fecal sterol excretion and reveals a G5G8-independent pathway for cholesterol elimination.Type I diabetes mellitus decreases in vivo macrophage-to-feces reverse cholesterol transport despite increased biliary sterol secretion in mice.ABCG5/G8 deficiency in mice reduces dietary triacylglycerol and cholesterol transport into the lymph.Combined effects of ezetimibe and phytosterols on cholesterol metabolism: a randomized, controlled feeding study in humans.The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance.Future therapeutic directions in reverse cholesterol transport.Regulation of reverse cholesterol transport - a comprehensive appraisal of available animal studies.Trust your gut: galvanizing nutritional interest in intestinal cholesterol metabolism for protection against cardiovascular diseases The Impairment of Macrophage-to-Feces Reverse Cholesterol Transport during Inflammation Does Not Depend on Serum Amyloid A.Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR.Liver X receptor agonist modulation of cholesterol efflux in mice with intestine-specific deletion of microsomal triglyceride transfer protein Intestinal SR-BI does not impact cholesterol absorption or transintestinal cholesterol efflux in mice.Biliary and nonbiliary contributions to reverse cholesterol transport.Transintestinal transport of the anti-inflammatory drug 4F and the modulation of transintestinal cholesterol efflux Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism.Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression.Insig proteins mediate feedback inhibition of cholesterol synthesis in the intestine.Sterol O-Acyltransferase 2-Driven Cholesterol Esterification Opposes Liver X Receptor-Stimulated Fecal Neutral Sterol Loss.Ezetimibe inhibits hepatic Niemann-Pick C1-Like 1 to facilitate macrophage reverse cholesterol transport in mice Differential impact of hepatic deficiency and total body inhibition of MTP on cholesterol metabolism and RCT in mice.Reverse cholesterol transport: from classical view to new insights.

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Activation of the liver X receptor stimulates trans-intestinal excretion of plasma cholesterol.

http://www.wikidata.org/entity/Q37339259

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 05 May 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Activation of the liver X rece ...... cretion of plasma cholesterol.

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Activation of the liver X rece ...... cretion of plasma cholesterol.

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Activation of the liver X rece ...... cretion of plasma cholesterol.

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Activation of the liver X rece ...... cretion of plasma cholesterol.

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Activation of the liver X rece ...... cretion of plasma cholesterol.

@en

Activation of the liver X rece ...... cretion of plasma cholesterol.

@nl

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JBC.M109.014860

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Journal of Biological Chemistry

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Activation of the liver X rece ...... cretion of plasma cholesterol.

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Albert K Groen

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Carlos L J Vrins

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Folkert Kuipers

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Hester van Meer

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Jelske N van der Veen

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Klaas Bijsterveld

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Rick Havinga

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Theo H van Dijk

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Uwe J F Tietge

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P2860

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL

The diversity of Rab proteins in vesicle transport

Initial hepatic removal of chylomicron remnants is unaffected but endocytosis is delayed in mice lacking the low density lipoprotein receptor.

Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion.

Mass isotopomer distribution analysis: a technique for measuring biosynthesis and turnover of polymers.

Mechanisms of disease: HDL metabolism as a target for novel therapies.

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19211-19219

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scholarly article

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10.1074/JBC.M109.014860

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29

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284

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2009-05-05T00:00:00Z

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19416968

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2740545

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