Aurora kinase A promotes inflammation and tumorigenesis in mice and human gastric neoplasia.
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Advances in targeted therapies and new promising targets in esophageal cancerAurora kinase A in gastrointestinal cancers: time to targetGlutathione Peroxidase 7 Suppresses Bile Salt-Induced Expression of Pro-Inflammatory Cytokines in Barrett's Carcinogenesis.TFF1 activates p53 through down-regulation of miR-504 in gastric cancerTP53/p53 alterations and Aurora A expression in progressor and non-progressor colectomies from patients with longstanding ulcerative colitisAURKA regulates JAK2-STAT3 activity in human gastric and esophageal cancers.Small molecule inhibitors in acute myeloid leukemia: from the bench to the clinicInhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.Aurora-A promotes chemoresistance in hepatocelluar carcinoma by targeting NF-kappaB/microRNA-21/PTEN signaling pathway.Suppression of Aurora-A-FLJ10540 signaling axis prohibits the malignant state of head and neck cancerCorrelation of decreased expression of PHLDA1 protein with malignant phenotype of gastric adenocarcinoma.Loss of TFF1 promotes Helicobacter pylori-induced β-catenin activation and gastric tumorigenesis.Expression of aurora kinase A correlates with the Wnt-modulator RACGAP1 in gastric cancer.Loss of mesenchymal bone morphogenetic protein signaling leads to development of reactive stroma and initiation of the gastric neoplastic cascadeAntitumor activity of TY-011 against gastric cancer by inhibiting Aurora A, Aurora B and VEGFR2 kinases.HDM2 regulation by AURKA promotes cell survival in gastric cancer.Recent advances and future trends in the targeted therapy of metastatic gastric cancer.Investigational therapies targeting signal transducer and activator of transcription 3 for the treatment of cancer.Emerging kinase inhibitors of the treatment of gastric cancer.Gastric cancer and gene copy number variation: emerging cancer drivers for targeted therapy.Epigenetic silencing of miR-137 induces drug resistance and chromosomal instability by targeting AURKA in multiple myeloma.An update on the pharmacokinetics and pharmacodynamics of alisertib, a selective Aurora kinase A inhibitor.Reduction of the tumorigenic potential of human retinoblastoma cell lines by TFF1 overexpression involves p53/caspase signaling and miR-18a regulation.Hint1 Up-Regulates IκBα by Targeting the β-TrCP Subunit of SCF E3 Ligase in Human Hepatocellular Carcinoma Cells.Cisplatin-resistant cancer cells are sensitive to Aurora kinase A inhibition by alisertib.Aurora-A Kinase: A Potent Oncogene and Target for Cancer Therapy.Aurora kinase A mediates c-Myc's oncogenic effects in hepatocellular carcinoma.Activation of EIF4E by Aurora Kinase A Depicts a Novel Druggable Axis in Everolimus-Resistant Cancer Cells.NF-κB Signaling in Gastric Cancer.Loss of Tff1 Promotes Pro-Inflammatory Phenotype with Increase in the Levels of RORγt+ T Lymphocytes and Il-17 in Mouse Gastric Neoplasia.Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGSAngiopoietin-like 4 Mediates Colonic Inflammation by Regulating Chemokine Transcript Stability via Tristetraprolin.MST4 kinase phosphorylates ACAP4 protein to orchestrate apical membrane remodeling during gastric acid secretion.Methylation of the HOXA10 promoter directs miR-196b-5p dependent cell proliferation and invasion of gastric cancer cells.MicroRNA-124-3p affects proliferation, migration and apoptosis of bladder cancer cells through targeting AURKA.The potential role of the NEK6, AURKA, AURKB, and PAK1 genes in adenomatous colorectal polyps and colorectal adenocarcinoma.IFRD1 polymorphisms and gastric cancer risk in a Chinese population.The Association Between AURKA Gene rs2273535 Polymorphism and Gastric Cancer Risk in a Chinese PopulationMASTL induces Colon Cancer progression and Chemoresistance by promoting Wnt/β-catenin signaling
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Aurora kinase A promotes inflammation and tumorigenesis in mice and human gastric neoplasia.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 29 August 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Aurora kinase A promotes infla ...... e and human gastric neoplasia.
@en
Aurora kinase A promotes infla ...... e and human gastric neoplasia.
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type
label
Aurora kinase A promotes infla ...... e and human gastric neoplasia.
@en
Aurora kinase A promotes infla ...... e and human gastric neoplasia.
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prefLabel
Aurora kinase A promotes infla ...... e and human gastric neoplasia.
@en
Aurora kinase A promotes infla ...... e and human gastric neoplasia.
@nl
P2093
P2860
P1433
P1476
Aurora kinase A promotes infla ...... e and human gastric neoplasia.
@en
P2093
Abbes Belkhiri
Ahmed Katsha
Dunfa Peng
H Charles Manning
Jeffrey Ecsedy
M Blanca Piazuelo
M Kay Washington
Mohammed N Tantawy
Mohammed Soutto
Pengcheng Lu
P2860
P304
1312-22.e1-8
P356
10.1053/J.GASTRO.2013.08.050
P407
P577
2013-08-29T00:00:00Z