CD5-CK2 binding/activation-deficient mice are resistant to experimental autoimmune encephalomyelitis: protection is associated with diminished populations of IL-17-expressing T cells in the central nervous system.
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A ligand for CD5 is CD5Autoimmune T cell responses in the central nervous systemMajor role of gamma delta T cells in the generation of IL-17+ uveitogenic T cells.Peroxisome proliferator-activated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunityCharacterization of autoreactive and bystander IL-17+ T cells induced in immunized C57BL/6 mice.The Dynamic Duo-Inflammatory M1 macrophages and Th17 cells in Rheumatic DiseasesMining CK2 in cancerExperimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS).Anti-inflammatory role of IL-17 in experimental autoimmune uveitisDistinct CD4+ helper T cells involved in primary and secondary responses to infection.Absence of regulatory T-cell control of TH1 and TH17 cells is responsible for the autoimmune-mediated pathology in chronic graft-versus-host disease.CD5-dependent CK2 activation pathway regulates threshold for T cell anergyCD5-CK2 Signaling Modulates Erk Activation and Thymocyte Survival.The Development of CK2 Inhibitors: From Traditional Pharmacology to in Silico Rational Drug Design.Naïve helper T cells with high CD5 expression have increased calcium signaling.Increased occurrence of protein kinase CK2 in astrocytes in Alzheimer's disease pathology.T-cell modulatory properties of CD5 and its role in antitumor immune responsesRetinoic acid inhibits CD25+ dendritic cell expansion and γδ T-cell activation in experimental autoimmune uveitis.Characterization of IL-17+ interphotoreceptor retinoid-binding protein-specific T cells in experimental autoimmune uveitis.Expression of interleukin-17RC protein in normal human tissuesCD5 plays an inhibitory role in the suppressive function of murine CD4(+) CD25(+) T(reg) cellsProtein kinase CK2, an important regulator of the inflammatory response?Lithium prevents and ameliorates experimental autoimmune encephalomyelitis.Protein kinase CK2 governs the molecular decision between encephalitogenic TH17 cell and Treg cell development.Drak2 regulates the survival of activated T cells and is required for organ-specific autoimmune disease.CD5 enhances Th17-cell differentiation by regulating IFN-γ response and RORγt localizationDeath receptor 5-targeted depletion of interleukin-23-producing macrophages, Th17, and Th1/17 associated with defective tyrosine phosphatase in mice and patients with rheumatoid arthritis.The immunomodulatory properties of the CD5 lymphocyte receptor in health and disease.Protein kinase CK2 in breast cancer: the CK2β regulatory subunit takes center stage in epithelial plasticity.Casein kinases as potential therapeutic targets.Constitutive Phosphorylation of STAT3 by the CK2-BLNK-CD5 Complex.CD275-Independent IL-17-Producing T Follicular Helper-like Cells in Lymphopenic Autoimmune-Prone Mice.Fli-1 regulates the DN2 to DN3 thymocyte transition and promotes γδ T-cell commitment by enhancing TCR signal strength.Increased numbers of thymic and peripheral CD4+ CD25+Foxp3+ cells in the absence of CD5 signaling.Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis.Protein Kinase CK2: An Emerging Regulator of Immunity.A Selective Biligand Inhibitor of CK2 Increases Caspase-3 Activity in Cancer Cells and Inhibits Platelet Aggregation.Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry.Tuning T Cell Signaling Sensitivity Alters the Behavior of CD4+ T Cells During an Immune Response.Inhibition of Casein Kinase 2 Protects Oligodendrocytes From Excitotoxicity by Attenuating JNK/p53 Signaling Cascade
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CD5-CK2 binding/activation-deficient mice are resistant to experimental autoimmune encephalomyelitis: protection is associated with diminished populations of IL-17-expressing T cells in the central nervous system.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2006
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
CD5-CK2 binding/activation-def ...... in the central nervous system.
@en
CD5-CK2 binding/activation-def ...... in the central nervous system.
@nl
type
label
CD5-CK2 binding/activation-def ...... in the central nervous system.
@en
CD5-CK2 binding/activation-def ...... in the central nervous system.
@nl
prefLabel
CD5-CK2 binding/activation-def ...... in the central nervous system.
@en
CD5-CK2 binding/activation-def ...... in the central nervous system.
@nl
P2093
P2860
P1476
CD5-CK2 binding/activation-def ...... in the central nervous system.
@en
P2093
Chander Raman
Robert C Axtell
Scott R Barnum
P2860
P304
P356
10.4049/JIMMUNOL.177.12.8542
P407
P577
2006-12-01T00:00:00Z