High-throughput screen for novel antimicrobials using a whole animal infection model.
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Whole organism high-content screening by label-free, image-based Bayesian classification for parasitic diseasesAutomated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin ZEvolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebratesDiversity, evolution and medical applications of insect antimicrobial peptidesTargeting Staphylococcus aureus Toxins: A Potential form of Anti-Virulence TherapyThe early bird catches the worm: new technologies for the Caenorhabditis elegans toolkitIn silico molecular comparisons of C. elegans and mammalian pharmacology identify distinct targets that regulate feedingA High-Throughput Small Molecule Screen for C. elegans Linker Cell Death InhibitorsThe evolutionarily conserved mediator subunit MDT-15/MED15 links protective innate immune responses and xenobiotic detoxificationStimulation of host immune defenses by a small molecule protects C. elegans from bacterial infectionPhosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegansBeyond Traditional Antimicrobials: A Caenorhabditis elegans Model for Discovery of Novel Anti-infectivesThe C. elegans model in toxicity testingRaloxifene attenuates Pseudomonas aeruginosa pyocyanin production and virulencePseudomonas aeruginosa disrupts Caenorhabditis elegans iron homeostasis, causing a hypoxic response and deathIt takes nerves to fight infections: insights on neuro-immune interactions from C. elegansIdentification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assayWhole animal automated platform for drug discovery against multi-drug resistant Staphylococcus aureusRepurposing salicylanilide anthelmintic drugs to combat drug resistant Staphylococcus aureusUsing C. elegans Forward and Reverse Genetics to Identify New Compounds with Anthelmintic ActivityIntroduction to the quantitative analysis of two-dimensional fluorescence microscopy images for cell-based screeningHigh-throughput fluorescence imaging approaches for drug discovery using in vitro and in vivo three-dimensional modelsDevelopment of gold nanoparticles coated with silica containing the antibiofilm drug cinnamaldehyde and their effects on pathogenic bacteriaSynthesis and antibacterial evaluation of a novel series of 2-(1,2-dihydro-3-oxo-3H-pyrazol-2-yl)benzothiazoles.Caenorhabditis elegans-based model systems for antifungal drug discovery.Using C. elegans for antimicrobial drug discovery.The garden of antimicrobial delightsA High-Content, Phenotypic Screen Identifies Fluorouridine as an Inhibitor of Pyoverdine Biosynthesis and Pseudomonas aeruginosa VirulenceA whole-organism screen identifies new regulators of fat storage.Caenorhabditis elegans-based in vivo screening of bioactives from marine sponge-associated bacteria against Vibrio alginolyticus.Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo.Insect-derived cecropins display activity against Acinetobacter baumannii in a whole-animal high-throughput Caenorhabditis elegans modelDiscovery of potential anti-infectives against Staphylococcus aureus using a Caenorhabditis elegans infection model.Lactobacillus zeae protects Caenorhabditis elegans from enterotoxigenic Escherichia coli-caused death by inhibiting enterotoxin gene expression of the pathogen.Pharmacological maintenance of protein homeostasis could postpone age-related diseaseIn vitro and in vivo activity of a novel sorafenib derivative SC5005 against MRSA.Systems biology of fungal infection.High-throughput screening in the C. elegans nervous system.An image analysis toolbox for high-throughput C. elegans assaysStochastic assembly produces heterogeneous communities in the Caenorhabditis elegans intestine.
P2860
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P2860
High-throughput screen for novel antimicrobials using a whole animal infection model.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
High-throughput screen for novel antimicrobials using a whole animal infection model.
@en
High-throughput screen for novel antimicrobials using a whole animal infection model.
@nl
type
label
High-throughput screen for novel antimicrobials using a whole animal infection model.
@en
High-throughput screen for novel antimicrobials using a whole animal infection model.
@nl
prefLabel
High-throughput screen for novel antimicrobials using a whole animal infection model.
@en
High-throughput screen for novel antimicrobials using a whole animal infection model.
@nl
P2093
P2860
P50
P356
P1433
P1476
High-throughput screen for novel antimicrobials using a whole animal infection model.
@en
P2093
Annie L Conery
Gabriele Casadei
Jonah Larkins-Ford
Ralph Mazitschek
Terence I Moy
P2860
P304
P356
10.1021/CB900084V
P577
2009-07-01T00:00:00Z