Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine.
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Effect of the inhaled anesthetics isoflurane, sevoflurane and desflurane on the neuropathogenesis of Alzheimer's disease (review)General anesthetics and β-amyloid proteinRegional and temporal profiles of calpain and caspase-3 activities in postnatal rat brain following repeated propofol administrationConsensus statement: First International Workshop on Anesthetics and Alzheimer's disease.Nitrous oxide plus isoflurane induces apoptosis and increases beta-amyloid protein levelsThe mitochondrial pathway of anesthetic isoflurane-induced apoptosis.Anesthetic-induced neurodegeneration mediated via inositol 1,4,5-trisphosphate receptorsComparison of neurodegeneration and cognitive impairment in neonatal mice exposed to propofol or isoflurane.Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice.Time-Dependent Effects of Anesthetic Isoflurane on Reactive Oxygen Species Levels in HEK-293 Cells.Isoflurane anesthesia induced persistent, progressive memory impairment, caused a loss of neural stem cells, and reduced neurogenesis in young, but not adult, rodents.Isoflurane induces endoplasmic reticulum stress and caspase activation through ryanodine receptorsGeneral anesthetic isoflurane modulates inositol 1,4,5-trisphosphate receptor calcium channel opening.The potential dual effects of anesthetic isoflurane on hypoxia-induced caspase-3 activation and increases in β-site amyloid precursor protein-cleaving enzyme levels.RNA interference-mediated silencing of BACE and APP attenuates the isoflurane-induced caspase activation.The role of calcium dysregulation in anesthetic-mediated neurotoxicity2-Deoxy-D-glucose attenuates isoflurane-induced cytotoxicity in an in vitro cell culture model of H4 human neuroglioma cellsIsoflurane/nitrous oxide anesthesia induces increases in NMDA receptor subunit NR2B protein expression in the aged rat brainMechanistic insights into neurotoxicity induced by anesthetics in the developing brain.Neurodevelopmental implications of the general anesthesia in neonate and infants.Arachidonic acid attenuates learning and memory dysfunction induced by repeated isoflurane anesthesia in rats.Propofol and magnesium attenuate isoflurane-induced caspase-3 activation via inhibiting mitochondrial permeability transition pore.Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairmentDual effects of isoflurane on proliferation, differentiation, and survival in human neuroprogenitor cells.Sevoflurane anesthesia in pregnant mice induces neurotoxicity in fetal and offspring mice.Isoflurane and sevoflurane increase interleukin-6 levels through the nuclear factor-kappa B pathway in neuroglioma cellsThe common inhalation anesthetic isoflurane induces caspase activation and increases amyloid beta-protein level in vivoThe common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels.Anesthesia, calcium homeostasis and Alzheimer's diseasePropofol compared with isoflurane inhibits mitochondrial metabolism in immature swine cerebral cortex.The potential dual effects of anesthetic isoflurane on Aβ-induced apoptosis.A mutation in β-amyloid precursor protein renders SH‑SY5Y cells vulnerable to isoflurane toxicity: The role of inositol 1,4,5‑trisphosphate receptors.Persistent mitoKATP Activation Is Involved in the Isoflurane-induced Cytotoxicity.Molecular Mechanisms of Anesthetic Neurotoxicity: A Review of the Current Literature.Lasting impact of general anaesthesia on the brain: mechanisms and relevance.Hydrogen sulfide attenuates isoflurane-induced neuroapoptosis and cognitive impairment in the developing rat brain.Memantine, a Low-Affinity NMDA Receptor Antagonist, Protects against Methylmercury-Induced Cytotoxicity of Rat Primary Cultured Cortical Neurons, Involvement of Ca2+ Dyshomeostasis Antagonism, and Indirect Antioxidation Effects.Anesthetic sevoflurane reduces levels of hippocalcin and postsynaptic density protein 95.Aggravation effect of isoflurane on Aβ(25-35)-induced apoptosis and tau hyperphosphorylation in PC12 cells.Isoflurane enhances the expression of cytochrome C by facilitation of NMDA receptor in developing rat hippocampal neurons in vitro.
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Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on April 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Isoflurane-induced caspase-3 a ...... an be attenuated by memantine.
@en
Isoflurane-induced caspase-3 a ...... an be attenuated by memantine.
@nl
type
label
Isoflurane-induced caspase-3 a ...... an be attenuated by memantine.
@en
Isoflurane-induced caspase-3 a ...... an be attenuated by memantine.
@nl
prefLabel
Isoflurane-induced caspase-3 a ...... an be attenuated by memantine.
@en
Isoflurane-induced caspase-3 a ...... an be attenuated by memantine.
@nl
P2093
P2860
P1476
Isoflurane-induced caspase-3 a ...... an be attenuated by memantine.
@en
P2093
Deborah J Culley
Fumito Ichinose
Gregory Crosby
Guohua Zhang
Yuanlin Dong
Zhongcong Xie
P2860
P304
P356
10.1523/JNEUROSCI.5694-07.2008
P407
P577
2008-04-01T00:00:00Z