Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons.
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Hyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates beta-catenin signaling and NFkappaB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance in breast tumor cellsRegulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72.CD44 cell adhesion moleculesHyaluronan-CD44 interaction promotes c-Src-mediated twist signaling, microRNA-10b expression, and RhoA/RhoC up-regulation, leading to Rho-kinase-associated cytoskeleton activation and breast tumor cell invasionProteoglycan forms of the lymphocyte homing receptor CD44 are alternatively spliced variants containing the v3 exonCD44 isoforms containing exon V3 are responsible for the presentation of heparin-binding growth factorIdentification of hyaluronic acid binding sites in the extracellular domain of CD44The Importance of CD44 as a Stem Cell Biomarker and Therapeutic Target in CancerMatrix Hyaluronan Promotes Specific MicroRNA Upregulation Leading to Drug Resistance and Tumor ProgressionPodoplanin - a small glycoprotein with many facesRoles of Proteoglycans and Glycosaminoglycans in Wound Healing and FibrosisCancer stem cells in colorectal cancer from pathogenesis to therapy: controversies and perspectivesStem cells in gastric cancerLeukocyte ligands for endothelial selectins: specialized glycoconjugates that mediate rolling and signaling under flowDemonstration of a melanoma-specific CD44 alternative splicing pattern that remains qualitatively stable, but shows quantitative changes during tumour progressionTargeting Tumor Cells with Anti-CD44 Antibody Triggers Macrophage-Mediated Immune Modulatory Effects in a Cancer Xenograft ModelPathophysiology of colorectal peritoneal carcinomatosis: Role of the peritoneumConcise Review: Emerging Role of CD44 in Cancer Stem Cells: A Promising Biomarker and Therapeutic TargetCD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating CellsModulation of CD44 Activity by A6-PeptideCD44 interaction with c-Src kinase promotes cortactin-mediated cytoskeleton function and hyaluronic acid-dependent ovarian tumor cell migrationHyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growthTIA-1 and TIAR activate splicing of alternative exons with weak 5' splice sites followed by a U-rich stretch on their own pre-mRNAsEvidence for the covalent binding of SHAP, heavy chains of inter-alpha-trypsin inhibitor, to hyaluronanExpression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathwayA splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowthMacrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complexThe RNA-binding protein TIA-1 is a novel mammalian splicing regulator acting through intron sequences adjacent to a 5' splice siteSynergistic effect of hyaluronate fragments in retinaldehyde-induced skin hyperplasia which is a Cd44-dependent phenomenonConservation of CD44 exon v3 functional elements in mammalsAn Analysis of Trafficking Receptors Shows that CD44 and P-Selectin Glycoprotein Ligand-1 Collectively Control the Migration of Activated Human T-Cells.Podoplanin associates with CD44 to promote directional cell migrationCD44 deficiency attenuates chronic murine ileitis.Inhibition of CD44 gene expression in human skin models, using self-delivery short interfering RNA administered by dissolvable microneedle arrays.CD44v/CD44s expression patterns are associated with the survival of pancreatic carcinoma patientsInferring alternative splicing patterns in mouse from a full-length cDNA library and microarray data.Constitutive intracellular expression and activation-induced cell surface up-regulation of CD44v3 in human T lymphocytes.CD44 and adhesion of normal and leukemic CD34+ cells to bone marrow stroma.The cellular and molecular basis of prostate cancer.Serum CD44 in non-Hodgkin's lymphoma.
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P2860
Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1992
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Genomic structure of DNA encod ...... 2 alternatively spliced exons.
@en
Genomic structure of DNA encod ...... 2 alternatively spliced exons.
@nl
type
label
Genomic structure of DNA encod ...... 2 alternatively spliced exons.
@en
Genomic structure of DNA encod ...... 2 alternatively spliced exons.
@nl
prefLabel
Genomic structure of DNA encod ...... 2 alternatively spliced exons.
@en
Genomic structure of DNA encod ...... 2 alternatively spliced exons.
@nl
P2093
P2860
P356
P1476
Genomic structure of DNA encod ...... 2 alternatively spliced exons.
@en
P2093
P2860
P304
12160-12164
P356
10.1073/PNAS.89.24.12160
P407
P577
1992-12-01T00:00:00Z