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Chemical analyses of wasp-associated streptomyces bacteria reveal a prolific potential for natural products discoveryNeurotoxic alkaloids: saxitoxin and its analogsSceptrin, a marine natural compound, inhibits cell motility in a variety of cancer cell lines.Blue-Print Autophagy: Potential for Cancer TreatmentMarine Invertebrate Metabolites with Anticancer Activities: Solutions to the "Supply Problem"Exploring the ocean for new drug developments: Marine pharmacologyAnthraquinones and Derivatives from Marine-Derived Fungi: Structural Diversity and Selected Biological ActivitiesContemporary Strategies for the Synthesis of Tetrahydropyran Derivatives: Application to Total Synthesis of Neopeltolide, a Marine Macrolide Natural ProductMarine Origin Polysaccharides in Drug Delivery Systems.Targeted metagenomics as a tool to tap into marine natural product diversity for the discovery and production of drug candidatesScrutinizing the scaffolds of marine biosynthetics from different source organisms: Gram-negative cultured bacterial products enter center stageLessons from the past and charting the future of marine natural products drug discovery and chemical biologyDithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptidesBiselyngbyasides, cytotoxic marine macrolides, are novel and potent inhibitors of the Ca(2+) pumps with a unique mode of bindingMarine-Derived Pharmaceuticals - Challenges and OpportunitiesVariation in tropical reef symbiont metagenomes defined by secondary metabolismFrondoside a suppressive effects on lung cancer survival, tumor growth, angiogenesis, invasion, and metastasisInhibition of both protease and helicase activities of hepatitis C virus NS3 by an ethyl acetate extract of marine sponge Amphimedon spWhat does it take to synergistically combine sub-potent natural products into drug-level potent combinations?Marine sediment-derived Streptomyces bacteria from British Columbia, Canada are a promising microbiota resource for the discovery of antimicrobial natural productsMerosesquiterpene Congeners from the Australian Sponge Hyrtios digitatus as Potential Drug Leads for Atherosclerosis DiseaseNew Metabolites and Bioactive Actinomycins from Marine-Derived Streptomyces sp. ZZ338Spithioneines A and B, Two New Bohemamine Derivatives Possessing Ergothioneine Moiety from a Marine-Derived Streptomyces spinoverrucosusNatural products as starting points for future anti-malarial therapies: going back to our roots?6-bromohypaphorine from marine nudibranch mollusk Hermissenda crassicornis is an agonist of human α7 nicotinic acetylcholine receptor.Antibacterial and antiyeast compounds from marine-derived bacteriaMetabolomic tools for secondary metabolite discovery from marine microbial symbiontsIdentification of the First Marine-Derived Opioid Receptor "Balanced" Agonist with a Signaling Profile That Resembles the EndorphinsSpirotetronate polyketides as leads in drug discovery.Anti-proliferative effect of methanolic extract of Gracilaria tenuistipitata on oral cancer cells involves apoptosis, DNA damage, and oxidative stress.Identification of Tight-Binding Plasmepsin II and Falcipain 2 Inhibitors in Aqueous Extracts of Marine Invertebrates by the Combination of Enzymatic and Interaction-Based Assays.In vitro and in vivo antineoplastic activity of a novel bromopyrrole and its potential mechanism of actionIdentification of CaV channel types expressed in muscle afferent neurons.Novel venom gene discovery in the platypus.A new lyngbyatoxin from the Hawaiian cyanobacterium Moorea producens.Evolving marine biomimetics for regenerative dentistry.Marine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance.Microtubule-stabilizing drugs from marine sponges: focus on peloruside A and zampanolideAnthracenedione derivatives as anticancer agents isolated from secondary metabolites of the mangrove endophytic fungiHemiasterlin analogues incorporating an aromatic, and heterocyclic type C-terminus: design, synthesis and biological evaluation.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 19 December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Drug development from marine natural products.
@en
Drug development from marine natural products.
@nl
type
label
Drug development from marine natural products.
@en
Drug development from marine natural products.
@nl
prefLabel
Drug development from marine natural products.
@en
Drug development from marine natural products.
@nl
P2093
P356
P1476
Drug development from marine natural products.
@en
P2093
Jonel P Saludes
Sarah L Lievens
Tadeusz F Molinski
P2888
P356
10.1038/NRD2487
P577
2008-12-19T00:00:00Z