Expression of human group II PLA2 in transgenic mice results in epidermal hyperplasia in the absence of inflammatory infiltrate.
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Cloning and characterization of novel mouse and human secretory phospholipase A(2)sStructures, enzymatic properties, and expression of novel human and mouse secretory phospholipase A(2)sPhospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic interventionNovel group V phospholipase A2 involved in arachidonic acid mobilization in murine P388D1 macrophagesArachidonic acid metabolism in brain physiology and pathology: lessons from genetically altered mouse modelsCloning of a gene for a novel epithelium-specific cytosolic phospholipase A2, cPLA2delta, induced in psoriatic skin.Novel immunomodulators for topical skin disease therapy.A bifunctional role for group IIA secreted phospholipase A2 in human rheumatoid fibroblast-like synoviocyte arachidonic acid metabolismPlatelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammationA novel anti-inflammatory role for secretory phospholipase A2 in immune complex-mediated arthritis.Hair follicular expression and function of group X secreted phospholipase A2 in mouse skin.Integrated lipidomics in the secreted phospholipase A(2) biology.Comparative efficacy of a secretory phospholipase A2 inhibitor with conventional anti-inflammatory agents in a rat model of antigen-induced arthritis.Detection and quantification of microparticles from different cellular lineages using flow cytometry. Evaluation of the impact of secreted phospholipase A2 on microparticle assessmentIncreased expression of human type IIa secretory phospholipase A2 antigen in arthritic synovium.A new era of secreted phospholipase A₂Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIAsPLA2 and the epidermal barrier.The role of group IIF-secreted phospholipase A2 in epidermal homeostasis and hyperplasiaThyroid hormone status regulates the expression of secretory phospholipasesNuclear corepressors mediate the repression of phospholipase A2 group IIa gene transcription by thyroid hormoneExpression and Function of Group IIE Phospholipase A2 in Mouse Skin.Analyses of group III secreted phospholipase A2 transgenic mice reveal potential participation of this enzyme in plasma lipoprotein modification, macrophage foam cell formation, and atherosclerosis.Group III secreted phospholipase A2 transgenic mice spontaneously develop inflammationAcidification in the epidermis and the role of secretory phospholipases.Secretory phospholipase A2 group IIA modulates insulin sensitivity and metabolism.Genetically modified laboratory mice with sebaceous glands abnormalities.Resistance of transgenic mice expressing human group II phospholipase A2 to Escherichia coli infection.Inhibitory effect of polyozellin on secretory group IIA phospholipase A2.Secretory group IIA phospholipase A(2) generates anti-apoptotic survival signals in kidney fibroblasts.Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing responseInhibitory Effect of FXa on Secretory Group IIA Phospholipase A2.Group V phospholipase A2 mediates barrier disruption of human pulmonary endothelial cells caused by LPS in vitroExpression of enhancing factor/phospholipase A2 in skin results in abnormal epidermis and increased sensitivity to chemical carcinogenesis.Secreted group IIA phospholipase A2 protects humans against the group B streptococcus: experimental and clinical evidence.Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition.Macrophage-specific expression of group IIA sPLA2 results in accelerated atherogenesis by increasing oxidative stress.CDP-choline significantly restores phosphatidylcholine levels by differentially affecting phospholipase A2 and CTP: phosphocholine cytidylyltransferase after stroke.Secretory phospholipase A2 increases SR-BI-mediated selective uptake from HDL but not biliary cholesterol secretion.Inhibitory effect of baicalin, baicalein and wogonin on secretory group IIA phospholipase A2.
P2860
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P2860
Expression of human group II PLA2 in transgenic mice results in epidermal hyperplasia in the absence of inflammatory infiltrate.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Expression of human group II P ...... ce of inflammatory infiltrate.
@en
Expression of human group II P ...... ce of inflammatory infiltrate.
@nl
type
label
Expression of human group II P ...... ce of inflammatory infiltrate.
@en
Expression of human group II P ...... ce of inflammatory infiltrate.
@nl
prefLabel
Expression of human group II P ...... ce of inflammatory infiltrate.
@en
Expression of human group II P ...... ce of inflammatory infiltrate.
@nl
P2093
P2860
P356
P1476
Expression of human group II P ...... ce of inflammatory infiltrate.
@en
P2093
C F Bennett
M E Swanson
M Y Chiang
R E Wallace
R H Felkner
T J Nevalainen
P2860
P304
P356
10.1172/JCI118664
P407
P577
1996-05-01T00:00:00Z