Role of RANKL-induced osteoclast formation and MMP-dependent matrix degradation in bone destruction by breast cancer metastasis.
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Anti-Inflammatory, Anti-Osteoclastogenic and Antioxidant Effects of Malva sylvestris Extract and Fractions: In Vitro and In Vivo StudiesThe reaction of bone to tumor growth from human breast cancer cells in a rat spine single metastasis model.RANK/RANKL/OPG system in the intervertebral disc.Matrix metalloproteinase (MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface.An MMP13-selective inhibitor delays primary tumor growth and the onset of tumor-associated osteolytic lesions in experimental models of breast cancer.Type I saikosaponins a and d inhibit osteoclastogenesis in bone marrow-derived macrophages and osteolytic activity of metastatic breast cancer cellsDirect Melanoma Cell Contact Induces Stromal Cell Autocrine Prostaglandin E2-EP4 Receptor Signaling That Drives Tumor Growth, Angiogenesis, and Metastasis.Immunolocalization of MMP9 and MMP2 in osteolytic metastasis originating from MDA-MB-231 human breast cancer cells.Influence of simultaneous targeting of the bone morphogenetic protein pathway and RANK/RANKL axis in osteolytic prostate cancer lesion in bone.Both cell-surface and secreted CSF-1 expressed by tumor cells metastatic to bone can contribute to osteoclast activation.The cellular and molecular mechanisms of bone invasion by oral squamous cell carcinoma.Animal model for mammary tumor growth in the bone microenvironment.The MET/Vascular Endothelial Growth Factor Receptor (VEGFR)-targeted Tyrosine Kinase Inhibitor Also Attenuates FMS-dependent Osteoclast Differentiation and Bone Destruction Induced by Prostate Cancer.Induction of integrin α2 in a highly bone metastatic human prostate cancer cell line: roles of RANKL and AR under three-dimensional suspension culture.Clinical significance of CYLD downregulation in breast cancer.Virulence factors associated with Aggregatibacter actinomycetemcomitans and their role in promoting periodontal diseases.In silico analysis of combinatorial microRNA activity reveals target genes and pathways associated with breast cancer metastasis.Treponema denticola upregulates MMP-2 activation in periodontal ligament cells: interplay between epigenetics and periodontal infection.The effect of down regulation of calcineurin Aα by lentiviral vector-mediated RNAi on the biological behavior of small-cell lung cancer and its bone metastasis.Propoxur enhances MMP-2 expression and the corresponding invasion of human breast cancer cells via the ERK/Nrf2 signaling pathway.Therapeutic and Preventive Effects of Osteoclastogenesis Inhibitory Factor on Osteolysis, Proliferation of Mammary Tumor Cell and Induction of Cancer Stem Cells in the Bone Microenvironment.Cutting to the Chase: How Matrix Metalloproteinase-2 Activity Controls Breast-Cancer-to-Bone Metastasis.Engineered 3D Silk-Based Metastasis Models: Interactions Between Human Breast Adenocarcinoma, Mesenchymal Stem Cells and Osteoblast-Like CellsRANKL inhibition: Clinical implications for the management of patients with multiple myeloma and solid tumors with bone metastasesFrom the Clinical Problem to the Basic Research-Co-Culture Models of Osteoblasts and Osteoclasts
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P2860
Role of RANKL-induced osteoclast formation and MMP-dependent matrix degradation in bone destruction by breast cancer metastasis.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on April 2003
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Role of RANKL-induced osteocla ...... n by breast cancer metastasis.
@en
Role of RANKL-induced osteocla ...... n by breast cancer metastasis.
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type
label
Role of RANKL-induced osteocla ...... n by breast cancer metastasis.
@en
Role of RANKL-induced osteocla ...... n by breast cancer metastasis.
@nl
prefLabel
Role of RANKL-induced osteocla ...... n by breast cancer metastasis.
@en
Role of RANKL-induced osteocla ...... n by breast cancer metastasis.
@nl
P2093
P2860
P356
P1476
Role of RANKL-induced osteocla ...... n by breast cancer metastasis.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.BJC.6600858
P407
P577
2003-04-01T00:00:00Z