Negative guidance factor-induced macropinocytosis in the growth cone plays a critical role in repulsive axon turning.
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The role of macropinocytosis in the propagation of protein aggregation associated with neurodegenerative diseasesGene-Silencing Screen for Mammalian Axon Regeneration Identifies Inpp5f (Sac2) as an Endogenous Suppressor of Repair after Spinal Cord InjuryAsymmetric endocytosis and remodeling of beta1-integrin adhesions during growth cone chemorepulsion by MAG.Serotonergic neurons migrate radially through the neuroepithelium by dynamin-mediated somal translocation.Myosin light chain kinase and Src control membrane dynamics in volume recovery from cell swellingThe COPI vesicle complex binds and moves with survival motor neuron within axons.Single vesicle imaging indicates distinct modes of rapid membrane retrieval during nerve growthRepulsive axon guidance cues ephrin-A2 and slit3 stop protrusion of the growth cone leading margin concurrently with inhibition of ADF/cofilin and ERM proteins.Myosin IIB isoform plays an essential role in the formation of two distinct types of macropinosomes.The growth cone cytoskeleton in axon outgrowth and guidance.Second messengers and membrane trafficking direct and organize growth cone steering.Shh signaling guides spatial pathfinding of raphespinal tract axons by multidirectional repulsionGrowth cone travel in space and time: the cellular ensemble of cytoskeleton, adhesion, and membrane.Sonic hedgehog is indirectly required for intraretinal axon pathfinding by regulating chemokine expression in the optic stalk.Protein kinase Cα and integrin-linked kinase mediate the negative axon guidance effects of Sonic hedgehog.SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation.Sonic hedgehog and Wnt: antagonists in morphogenesis but collaborators in axon guidance.JosD1, a membrane-targeted deubiquitinating enzyme, is activated by ubiquitination and regulates membrane dynamics, cell motility, and endocytosisDysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model.Rab5 and Rab4 regulate axon elongation in the Xenopus visual system.Endocytosis unplugged: multiple ways to enter the cell.Antibody-targeted nanoparticles for cancer therapy.Exocytic and endocytic membrane trafficking in axon development.Deregulation of the actin cytoskeleton and macropinocytosis in response to phorbol ester by the mutant protein kinase C gamma that causes spinocerebellar ataxia type 14.Protein aggregates stimulate macropinocytosis facilitating their propagationMegalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development.Isolation and culture of dissociated sensory neurons from chick embryos.Hedgehog signaling regulates size of the dorsal aortae and density of the plexus during avian vascular development.Functional Genome-wide Screen Identifies Pathways Restricting Central Nervous System Axonal Regeneration.
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P2860
Negative guidance factor-induced macropinocytosis in the growth cone plays a critical role in repulsive axon turning.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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name
Negative guidance factor-induc ...... ole in repulsive axon turning.
@en
Negative guidance factor-induc ...... ole in repulsive axon turning.
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type
label
Negative guidance factor-induc ...... ole in repulsive axon turning.
@en
Negative guidance factor-induc ...... ole in repulsive axon turning.
@nl
prefLabel
Negative guidance factor-induc ...... ole in repulsive axon turning.
@en
Negative guidance factor-induc ...... ole in repulsive axon turning.
@nl
P2093
P2860
P1476
Negative guidance factor-induc ...... ole in repulsive axon turning.
@en
P2093
Adrianne L Kolpak
Clive Standley
Daorong Guo
Karl Bellve
Kevin Fogarty
Zheng-Zheng Bao
P2860
P304
10488-10498
P356
10.1523/JNEUROSCI.2355-09.2009
P407
P577
2009-08-01T00:00:00Z