Untangling the complex web of IL-4- and IL-13-mediated signaling pathways.
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IL-4R drives dedifferentiation, mitogenesis, and metastasis in rhabdomyosarcomaCytokines in psoriasisA molecular perspective on TH2-promoting cytokine receptors in patients with allergic disease.How does high-fat diet induce adipose tissue fibrosis?Evolution of Th2 responses: characterization of IL-4/13 in sea bass (Dicentrarchus labrax L.) and studies of expression and biological activityInterleukin-13 directly promotes oesophagus production of CCL11 and CCL24 and the migration of eosinophils.Establishment of extracellular signal-regulated kinase 1/2 bistability and sustained activation through Sprouty 2 and its relevance for epithelial function.CXCR3 Requirement for the Interleukin-13-Mediated Up-Regulation of Interleukin-13Rα2 in Pulmonary FibroblastsNarrative review: the role of Th2 immune pathway modulation in the treatment of severe asthma and its phenotypes.Cytokine profiles in asthma families depend on age and phenotype.The Role of Innate Lymphoid Cells in Immune-Mediated Liver Diseases.Subnormal cytokine profile in the tear fluid of keratoconus patients.In vivo regulation of the allergic response by the IL-4 receptor alpha chain immunoreceptor tyrosine-based inhibitory motifTGF-β-mediated sustained ERK1/2 activity promotes the inhibition of intracellular growth of Mycobacterium avium in epithelioid cells surrogates.Oclacitinib (APOQUEL(®)) is a novel Janus kinase inhibitor with activity against cytokines involved in allergy.The role of commensal bacteria in the regulation of sensitization to food allergens.5A, an apolipoprotein A-I mimetic peptide, attenuates the induction of house dust mite-induced asthmaReduced interleukin-4 receptor α expression on CD8+ T cells correlates with higher quality anti-viral immunity.IgE-mediated systemic anaphylaxis and impaired tolerance to food antigens in mice with enhanced IL-4 receptor signaling.Absence of the common gamma chain (γ(c)), a critical component of the Type I IL-4 receptor, increases the severity of allergic lung inflammation.TH2-Polarized CD4(+) T Cells and Macrophages Limit Efficacy of Radiotherapy.Murine model of chronic L. (Viannia) panamensis infection: role of IL-13 in disease.Non-canonical alternatives: what a macrophage is 4Dynamic Redox Regulation of IL-4 Signaling.IL-4 and TGF-beta 1 counterbalance one another while regulating mast cell homeostasis.Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasisHierarchical IL-5 expression defines a subpopulation of highly differentiated human Th2 cells.Innate immunostimulatory properties of allergens and their relevance to food allergy.New and emerging therapies for asthma.IL-8, IL-10, TGF-β, and GCSF levels were increased in severe persistent allergic asthma patients with the anti-IgE treatmentJAK-STAT1/3-induced expression of signal sequence-encoding proopiomelanocortin mRNA in lymphocytes reduces inflammatory pain in ratsDifferential T-helper cell polarization after allergen-specific stimulation of autologous dendritic cells in polysensitized allergic patients.Safety, tolerability and pharmacokinetics of a human anti-interleukin-13 monoclonal antibody (CNTO 5825) in an ascending single-dose first-in-human study.Role of interleukin 4 and its receptor in clinical presentation of chronic extrinsic allergic alveolitis: a pilot studyEndoplasmic reticulum stress impairs IL-4/IL-13 signaling through C/EBPβ-mediated transcriptional suppression.Interleukin-4 induces senescence in human renal carcinoma cell lines through STAT6 and p38 MAPK.Allergy-specific Phenome-Wide Association Study for Immunogenes in Turkish Children.Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences.Parasite-antigen driven expansion of IL-5(-) and IL-5(+) Th2 human subpopulations in lymphatic filariasis and their differential dependence on IL-10 and TGFβ.Transgenic modelling of cytokine polarization in the lung.
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Untangling the complex web of IL-4- and IL-13-mediated signaling pathways.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Untangling the complex web of IL-4- and IL-13-mediated signaling pathways.
@en
Untangling the complex web of IL-4- and IL-13-mediated signaling pathways.
@nl
type
label
Untangling the complex web of IL-4- and IL-13-mediated signaling pathways.
@en
Untangling the complex web of IL-4- and IL-13-mediated signaling pathways.
@nl
prefLabel
Untangling the complex web of IL-4- and IL-13-mediated signaling pathways.
@en
Untangling the complex web of IL-4- and IL-13-mediated signaling pathways.
@nl
P2860
P1433
P1476
Untangling the complex web of IL-4- and IL-13-mediated signaling pathways.
@en
P2093
Fred D Finkelman
Marsha Wills-Karp
P2860
P356
10.1126/SCISIGNAL.1.51.PE55
P577
2008-12-23T00:00:00Z