Foxo1 links hyperglycemia to LDL oxidation and endothelial nitric oxide synthase dysfunction in vascular endothelial cells.
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ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related DiseasesRedox regulation of FoxO transcription factorsForkhead box transcription factor 1: role in the pathogenesis of diabetic cardiomyopathyRedox regulation of endothelial cell fateCeacam1 deletion causes vascular alterations in large vesselsThe impact of macrophage insulin resistance on advanced atherosclerotic plaque progression.Hyperglycaemia enhances nitric oxide production in diabetes: a study from South Indian patients.Role of nitric oxide in placental vascular development and function.Homozygosity for an allele encoding deacetylated FoxO1 protects macrophages from cholesterol-induced inflammation without increasing apoptosis.Forkhead box O-1 modulation improves endothelial insulin resistance in human obesity.FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis.Increased atherosclerosis and endothelial dysfunction in mice bearing constitutively deacetylated alleles of Foxo1 gene.Functional Regression Models for Epistasis Analysis of Multiple Quantitative Traits.FOXO1 mediates the autocrine effect of endothelin-1 on endothelial cell survival.Liver sinusoidal endothelial cells link hyperinsulinemia to hepatic insulin resistanceExpanded granulocyte/monocyte compartment in myeloid-specific triple FoxO knockout increases oxidative stress and accelerates atherosclerosis in miceFOXO1-mediated activation of Akt plays a critical role in vascular homeostasis.Exposure to high or low glucose levels accelerates the appearance of markers of endothelial cell senescence and induces dysregulation of nitric oxide synthaseSodium Glucose Co-transporter Type 2 (SGLT2) Inhibitors: Targeting the Kidney to Improve Glycemic Control in Diabetes MellitusFoxO1 is crucial for sustaining cardiomyocyte metabolism and cell survival.Forkhead box class O family member proteins: The biology and pathophysiological roles in diabetes.Metabolic Regulation of Angiogenesis in Diabetes and Aging.Insights into the molecular mechanisms of diabetes-induced endothelial dysfunction: focus on oxidative stress and endothelial progenitor cells.The Contribution of Singlet Oxygen to Insulin Resistance.Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects.Endothelial Cell Metabolism.Recurrent hypoinsulinemic hyperglycemia in neonatal rats increases PARP-1 and NF-κB expression and leads to microglial activation in the cerebral cortex.
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Foxo1 links hyperglycemia to LDL oxidation and endothelial nitric oxide synthase dysfunction in vascular endothelial cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 07 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Foxo1 links hyperglycemia to L ...... in vascular endothelial cells.
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Foxo1 links hyperglycemia to L ...... in vascular endothelial cells.
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type
label
Foxo1 links hyperglycemia to L ...... in vascular endothelial cells.
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Foxo1 links hyperglycemia to L ...... in vascular endothelial cells.
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Foxo1 links hyperglycemia to L ...... in vascular endothelial cells.
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Foxo1 links hyperglycemia to L ...... in vascular endothelial cells.
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Foxo1 links hyperglycemia to L ...... in vascular endothelial cells.
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Alexander S Banks
Carrie L Welch
Jun Tanaka
Michihiro Matsumoto
Ronald A DePinho
Tadahiro Kitamura
Yukari Ido-Kitamura
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P304
P356
10.2337/DB09-0167
P407
P577
2009-07-07T00:00:00Z