Hensin, a new collecting duct protein involved in the in vitro plasticity of intercalated cell polarity
about
DMBT1, a regulator of mucosal homeostasis through the linking of mucosal defense and regeneration?DMBT1 expression is down-regulated in breast cancerMolecular mechanisms and regulation of urinary acidificationConversion of ES cells to columnar epithelia by hensin and to squamous epithelia by lamininInduction of terminal differentiation in epithelial cells requires polymerization of hensin by galectin 3Kanadaptin is a protein that interacts with the kidney but not the erythroid form of band 3Effects of Muclin (Dmbt1) deficiency on the gastrointestinal system.Deletion of hensin/DMBT1 blocks conversion of beta- to alpha-intercalated cells and induces distal renal tubular acidosis.Remodeling the cellular profile of collecting ducts by chronic carbonic anhydrase inhibition.Global transcriptional response to carbonic anhydrase IX deficiency in the mouse stomachp63+ ureteric bud tip cells are progenitors of intercalated cells.Proliferation of acid-secretory cells in the kidney during adaptive remodelling of the collecting duct.Prostatic expression of hensin, a protein implicated in epithelial terminal differentiation.Renal vacuolar H+-ATPase.A variant form of the human deleted in malignant brain tumor 1 (DMBT1) gene shows increased expression in inflammatory bowel diseases and interacts with dimeric trefoil factor 3 (TFF3).Acid incubation reverses the polarity of intercalated cell transporters, an effect mediated by hensin.Terminal differentiation of epithelia.Apical polarity of N-CAM and EMMPRIN in retinal pigment epithelium resulting from suppression of basolateral signal recognitionHensin remodels the apical cytoskeleton and induces columnarization of intercalated epithelial cells: processes that resemble terminal differentiationRole of integrins in the assembly and function of hensin in intercalated cellsGalectin-3 mediates oligomerization of secreted hensin using its carbohydrate-recognition domain.Secreted cyclophilin A, a peptidylprolyl cis-trans isomerase, mediates matrix assembly of hensin, a protein implicated in epithelial differentiation.Differentiation of intercalated cells in the kidney.Renal acid-base regulation: new insights from animal models.Increased expression of deleted in malignant brain tumors (DMBT1) gene in precancerous gastric lesions: Findings from human and animal studies.Aberrant epithelial-mesenchymal Hedgehog signaling characterizes Barrett's metaplasia.Hensin: a matrix protein determinant of epithelial polarity.Hensin, the polarity reversal protein, is encoded by DMBT1, a gene frequently deleted in malignant gliomas.Only multimeric hensin located in the extracellular matrix can induce apical endocytosis and reverse the polarity of intercalated cells.Expression of transfected human Na+/H+ exchanger (NHE-1) in the the basolateral membrane of opossum kidney cells.The effect of apical and basolateral lipids on the function of the band 3 anion exchange protein.
P2860
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P2860
Hensin, a new collecting duct protein involved in the in vitro plasticity of intercalated cell polarity
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Hensin, a new collecting duct ...... of intercalated cell polarity
@en
Hensin, a new collecting duct ...... of intercalated cell polarity.
@nl
type
label
Hensin, a new collecting duct ...... of intercalated cell polarity
@en
Hensin, a new collecting duct ...... of intercalated cell polarity.
@nl
prefLabel
Hensin, a new collecting duct ...... of intercalated cell polarity
@en
Hensin, a new collecting duct ...... of intercalated cell polarity.
@nl
P2093
P2860
P356
P1476
Hensin, a new collecting duct ...... of intercalated cell polarity
@en
P2093
P2860
P304
P356
10.1172/JCI119044
P407
P577
1996-11-01T00:00:00Z