Drug interactions at the blood-brain barrier: fact or fantasy?
about
Progress and perspectives on targeting nanoparticles for brain drug delivery.Membrane transporters in drug developmentTargeting therapeutics across the blood brain barrier (BBB), prerequisite towards thrombolytic therapy for cerebrovascular disorders-an overview and advancementsPathways for small molecule delivery to the central nervous system across the blood-brain barrier.Pgp-mediated interaction between (R)-[11C]verapamil and tariquidar at the human blood-brain barrier: a comparison with rat dataRegional P-glycoprotein activity and inhibition at the human blood-brain barrier as imaged by positron emission tomography.In vivo assessment of the permeability of the blood-brain barrier and blood-retinal barrier to fluorescent indoline derivatives in zebrafish.Domperidone as an unintended antipsychoticMolecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: similarities and differencesA comprehensive non-clinical evaluation of the CNS penetration potential of antimuscarinic agents for the treatment of overactive bladder.Interactions between antidepressants and P-glycoprotein at the blood-brain barrier: clinical significance of in vitro and in vivo findings.P-glycoprotein-based loperamide-cyclosporine drug interaction at the rat blood-brain barrier: prediction from in vitro studies and extrapolation to humans.Factors Governing P-Glycoprotein-Mediated Drug-Drug Interactions at the Blood-Brain Barrier Measured with Positron Emission Tomography.Metformin inhibits leptin-induced growth and migration of glioblastoma cells.Modeling cyclosporine A inhibition of the distribution of a P-glycoprotein PET ligand, 11C-verapamil, into the maternal brain and fetal liver of the pregnant nonhuman primate: impact of tissue blood flow and site of inhibition.A review of multifunctional nanoemulsion systems to overcome oral and CNS drug delivery barriers.Monoclonal antibodies in neuro-oncology: Getting past the blood-brain barrier.Use of physiologically based pharmacokinetic modeling for assessment of drug-drug interactions.The right compound in the right assay at the right time: an integrated discovery DMPK strategy.Species differences in drug transporters and implications for translating preclinical findings to humans.Advances in brain targeting and drug delivery of anti-HIV therapeutic agents.Why clinical modulation of efflux transport at the human blood-brain barrier is unlikely: the ITC evidence-based position.Neuronal toxicity of efavirenz: a systematic review.Overcoming the blood-brain barrier in chemotherapy treatment of pediatric brain tumors.Using positron emission tomography to study transporter-mediated drug-drug interactions in tissues.Strategies for overcoming the blood-brain barrier for the treatment of brain metastases.Drug transporters in the central nervous system.Mechanisms and therapeutic potential of inhibiting drug efflux transporters.Nanomedicine and nanotoxicology: the pros and cons for neurodegeneration and brain cancer.Effect of P-glycoprotein inhibition at the blood-brain barrier on brain distribution of (R)-[11 C]verapamil in elderly vs. young subjects.Use of PET Imaging to Evaluate Transporter-Mediated Drug-Drug Interactions.Drug-Drug Interactions of a Novel κ-Opioid Receptor Agonist, Nalfurafine Hydrochloride, Involving the P-Glycoprotein.Antiepileptic drugs alter the expression of placental carriers: An in vitro study in a human placental cell line.Imaging transporters: Transforming diagnostic and therapeutic development.Synthesis, characterization and brain targeting potential of paclitaxel loaded thiamine-PPI nanoconjugates.Quinidine as an ABCB1 probe for testing drug interactions at the blood-brain barrier: an in vitro in vivo correlation study.Central nervous system penetration of antiretroviral drugs: pharmacokinetic, pharmacodynamic and pharmacogenomic considerations.Interactions of ABCG2 (BCRP) with epidermal growth factor receptor kinase inhibitors developed for molecular imaging.In vivo induction of P-glycoprotein expression at the mouse blood-brain barrier: an intracerebral microdialysis study.The use of microdialysis techniques in mice to study P-gp function at the blood-brain barrier.
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P2860
Drug interactions at the blood-brain barrier: fact or fantasy?
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 22 April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Drug interactions at the blood-brain barrier: fact or fantasy?
@en
Drug interactions at the blood-brain barrier: fact or fantasy?
@nl
type
label
Drug interactions at the blood-brain barrier: fact or fantasy?
@en
Drug interactions at the blood-brain barrier: fact or fantasy?
@nl
prefLabel
Drug interactions at the blood-brain barrier: fact or fantasy?
@en
Drug interactions at the blood-brain barrier: fact or fantasy?
@nl
P2093
P2860
P1476
Drug interactions at the blood-brain barrier: fact or fantasy?
@en
P2093
Jashvant D Unadkat
Peng Hsiao
P2860
P304
P356
10.1016/J.PHARMTHERA.2009.03.017
P577
2009-04-22T00:00:00Z