Complete protection from repeated vaginal simian-human immunodeficiency virus exposures in macaques by a topical gel containing tenofovir alone or with emtricitabine.
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Tenofovir-based pre-exposure prophylaxis for HIV preventionEffectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in womenPreexposure prophylaxis for HIV prevention: where have we been and where are we going?Preventing HIV infection: pre-exposure and postexposure prophylaxisMicrobicides: topical prevention against HIVRectal application of a highly osmolar personal lubricant in a macaque model induces acute cytotoxicity but does not increase risk of SHIV infectionIn vivo binding and retention of CD4-specific DARPin 57.2 in macaquesA Novel Microbicide/Contraceptive Intravaginal Ring Protects Macaque Genital Mucosa against SHIV-RT Infection Ex VivoAn antiretroviral/zinc combination gel provides 24 hours of complete protection against vaginal SHIV infection in macaquesDrug transporters in tissues and cells relevant to sexual transmission of HIV: Implications for drug deliveryIn vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicideT cell chemo-vaccination effects after repeated mucosal SHIV exposures and oral pre-exposure prophylaxisDrug synergy of tenofovir and nanoparticle-based antiretrovirals for HIV prophylaxisGlobal expression of molecular transporters in the human vaginal tract: implications for HIV chemoprophylaxisTopical Delivery of Tenofovir Disoproxil Fumarate and Emtricitabine from Pod-Intravaginal Rings Protects Macaques from Multiple SHIV ExposuresSHIV-162P3 infection of rhesus macaques given maraviroc gel vaginally does not involve resistant virusesA multi-compartment, single and multiple dose pharmacokinetic study of the vaginal candidate microbicide 1% tenofovir gelCharacteristics of HIV-1 serodiscordant couples enrolled in a clinical trial of antiretroviral pre-exposure prophylaxis for HIV-1 preventionStimulus-responsive hydrogels: Theory, modern advances, and applications.HIV prevention transformed: the new prevention research agendaFormulation, pharmacokinetics and pharmacodynamics of topical microbicides.Tenofovir-based preexposure prophylaxis for HIV infection among African women.Single-agent tenofovir versus combination emtricitabine plus tenofovir for pre-exposure prophylaxis for HIV-1 acquisition: an update of data from a randomised, double-blind, phase 3 trial.Targeting Trojan Horse leukocytes for HIV prevention.Increased Dapivirine tissue accumulation through vaginal film codelivery of dapivirine and Tenofovir.Advances in the Development of Microbicides for the Prevention of HIV Infection.A randomized trial to assess anti-HIV activity in female genital tract secretions and soluble mucosal immunity following application of 1% tenofovir gel.Rapid dissemination of SIV follows multisite entry after rectal inoculation.Pharmacokinetics and preliminary safety study of pod-intravaginal rings delivering antiretroviral combinations for HIV prophylaxis in a macaque model.Bridging the gap between preclinical and clinical microbicide trials: blind evaluation of candidate gels in murine models of efficacy and safety.Short communication: Viremic control is independent of repeated low-dose SHIVSF162p3 exposures.Short communication: a repeated simian human immunodeficiency virus reverse transcriptase/herpes simplex virus type 2 cochallenge macaque model for the evaluation of microbicidesPrevention of vaginal SHIV transmission in macaques by a coitally-dependent Truvada regimen.Preventing mucosal HIV transmission with topical microbicides: challenges and opportunities.Analyses of nanoformulated antiretroviral drug charge, size, shape and content for uptake, drug release and antiviral activities in human monocyte-derived macrophages.Increased susceptibility to vaginal simian/human immunodeficiency virus transmission in pig-tailed macaques coinfected with Chlamydia trachomatis and Trichomonas vaginalisEvaluation of Rapidly Disintegrating Vaginal Tablets of Tenofovir, Emtricitabine and Their Combination for HIV-1 Prevention.The nonnucleoside reverse transcriptase inhibitor MIV-150 in carrageenan gel prevents rectal transmission of simian/human immunodeficiency virus infection in macaques.Topical prophylaxis for HIV prevention in women: becoming a reality.Pre-exposure prophylaxis of HIV: A right way to go or a long way to go?
P2860
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P2860
Complete protection from repeated vaginal simian-human immunodeficiency virus exposures in macaques by a topical gel containing tenofovir alone or with emtricitabine.
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 05 August 2009
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Complete protection from repea ...... r alone or with emtricitabine.
@en
Complete protection from repea ...... r alone or with emtricitabine.
@nl
type
label
Complete protection from repea ...... r alone or with emtricitabine.
@en
Complete protection from repea ...... r alone or with emtricitabine.
@nl
prefLabel
Complete protection from repea ...... r alone or with emtricitabine.
@en
Complete protection from repea ...... r alone or with emtricitabine.
@nl
P2093
P2860
P356
P1433
P1476
Complete protection from repea ...... r alone or with emtricitabine.
@en
P2093
Amy Martin
Charles Dobard
Chou-Pong Pau
Debra L Hanson
Ellen Kersh
Francis J Novembre
Hongwei Jia
J Gerardo Garcia-Lerma
James Smith
Mian-er Cong
P2860
P304
10358-10365
P356
10.1128/JVI.01073-09
P407
P577
2009-08-05T00:00:00Z