Cell adhesion in vascular biology. New insights into integrin-ligand interaction.
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Calcium modulates force sensing by the von Willebrand factor A2 domainThe von willebrand factor A3 domain does not contain a metal ion-dependent adhesion site motifFertilin beta and other ADAMs as integrin ligands: insights into cell adhesion and fertilizationBinding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformationIntegrin α5β1 facilitates cancer cell invasion through enhanced contractile forces.In vitro selection of fibronectin gain-of-function mutationsComparison of the solution conformations of a cell-adhesive peptide LBE and its reverse sequence EBL.A minimized human integrin alpha(5)beta(1) that retains ligand recognition.The leukocyte integrins.The breast cancer beta 4 integrin and endothelial human CLCA2 mediate lung metastasis.Contractile forces contribute to increased glycosylphosphatidylinositol-anchored receptor CD24-facilitated cancer cell invasion.Experimental support for a beta-propeller domain in integrin alpha-subunits and a calcium binding site on its lower surface.Complementary roles for receptor clustering and conformational change in the adhesive and signaling functions of integrin alphaIIb beta3Defining fibronectin's cell adhesion synergy site by site-directed mutagenesis.Integrin alpha(M)beta(2)-mediated cell migration to fibrinogen and its recognition peptides.The role of endothelial mechanosensitive genes in atherosclerosis and omics approaches.Conformational changes in tertiary structure near the ligand binding site of an integrin I domain.On the activation of integrin αIIbβ3: outside-in and inside-out pathways.A two-amino acid insertion in the Cys146- Cys167 loop of the alphaIIb subunit is associated with a variant of Glanzmann thrombasthenia. Critical role of Asp163 in ligand binding.Neisseria gonorrhoeae pilin glycan contributes to CR3 activation during challenge of primary cervical epithelial cellsThe sensors and regulators of cell-matrix surveillance in anoikis resistance of tumors.Novel anti-cancer compounds for developing combinatorial therapies to target anoikis-resistant tumors.Identification and characterization of two cation binding sites in the integrin beta 3 subunit.Effects of I domain deletion on the function of the beta2 integrin lymphocyte function-associated antigen-1.Phagocytized beads reduce the α5β1 integrin facilitated invasiveness of cancer cells by regulating cellular stiffness.Cloning and characterization of the osteoarthritis-associated gene DVWA.Calcium integrin-binding protein activates platelet integrin alpha IIbbeta 3.Probing chemical and conformational differences in the resting and active conformers of platelet integrin alpha(IIb)beta(3).Multiple discontinuous ligand-mimetic antibody binding sites define a ligand binding pocket in integrin alpha(IIb)beta(3).Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin alpha5 beta1.High affinity ligand binding by integrins does not involve head separation.The I domain of integrin LFA-1 interacts with ICAM-1 domain 1 at residue Glu-34 but not Gln-73.Asp-698 and Asp-811 of the integrin alpha4-subunit are critical for the formation of a functional heterodimer.Fine mapping of inhibitory anti-alpha5 monoclonal antibody epitopes that differentially affect integrin-ligand binding.Agonist-specific structural rearrangements of integrin alpha IIbbeta 3. Confirmation of the bent conformation in platelets at rest and after activation.A new model of dual interacting ligand binding sites on integrin alphaIIbbeta3.Molecular identification of the cross-reacting epitope on alphaM beta2 integrin I domain recognized by anti-alphaIIb beta3 monoclonal antibody 7E3 and its involvement in leukocyte adherence.Current Anti-Integrin Therapy for Ocular Disease.Molecular Basis of Ligand Recognition by Integrin α5β1Molecular Basis of Ligand Recognition by Integrin α5β1
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Cell adhesion in vascular biology. New insights into integrin-ligand interaction.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1997
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Cell adhesion in vascular biology. New insights into integrin-ligand interaction.
@en
Cell adhesion in vascular biology. New insights into integrin-ligand interaction.
@nl
type
label
Cell adhesion in vascular biology. New insights into integrin-ligand interaction.
@en
Cell adhesion in vascular biology. New insights into integrin-ligand interaction.
@nl
prefLabel
Cell adhesion in vascular biology. New insights into integrin-ligand interaction.
@en
Cell adhesion in vascular biology. New insights into integrin-ligand interaction.
@nl
P2860
P356
P1476
Cell adhesion in vascular biology. New insights into integrin-ligand interaction.
@en
P2093
J C Loftus
R C Liddington
P2860
P304
P356
10.1172/JCI119408
P407
P577
1997-05-01T00:00:00Z