Protecting against cerebrovascular injury: contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia.
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Neuroprotection and antioxidantsMethylophiopogonanone A Protects against Cerebral Ischemia/Reperfusion Injury and Attenuates Blood-Brain Barrier Disruption In VitroMammalian lipoxygenases and their biological relevance12- and 15-lipoxygenases in adipose tissue inflammationFunctional and pathological roles of the 12- and 15-lipoxygenasesTherapies targeting lipid peroxidation in traumatic brain injuryPathophysiology of glia in perinatal white matter injury.Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapiesIncreased nuclear apoptosis-inducing factor after transient focal ischemia: a 12/15-lipoxygenase-dependent organelle damage pathway.The 12/15-lipoxygenase as an emerging therapeutic target for Alzheimer's diseaseIron mediates endothelial cell damage and blood-brain barrier opening in the hippocampus after transient forebrain ischemia in rats.Loss of miR-29b following acute ischemic stroke contributes to neural cell death and infarct size.The potential of 12/15-lipoxygenase inhibitors in stroke therapy.Cell type-specific dependency on the PI3K/Akt signaling pathway for the endogenous Epo and VEGF induction by baicalein in neurons versus astrocytes.The developing oligodendrocyte: key cellular target in brain injury in the premature infantPolyunsaturated fatty acid metabolism signature in ischemia differs from reperfusion in mouse intestine.12/15-Lipoxygenase metabolites of arachidonic acid activate PPARĪ³: a possible neuroprotective effect in ischemic brainDietary flavonoids are neuroprotective through Nrf2-coordinated induction of endogenous cytoprotective proteins.DOR activation inhibits anoxic/ischemic Na+ influx through Na+ channels via PKC mechanisms in the cortexSTAT-dependent upregulation of 12/15-lipoxygenase contributes to neuronal injury after stroke.Following experimental stroke, the recovering brain is vulnerable to lipoxygenase-dependent semaphorin signalingInhibition of 12/15-lipoxygenase as therapeutic strategy to treat strokeLipoxygenase: an emerging target for stroke therapyCD47 gene knockout protects against transient focal cerebral ischemia in miceDesign of a novel thiophene inhibitor of 15-lipoxygenase-1 with both anti-inflammatory and neuroprotective propertiesEffect of human 15-lipoxygenase-1 metabolites on vascular function in mouse mesenteric arteries and hearts.12/15-lipoxygenase expression is increased in oligodendrocytes and microglia of periventricular leukomalaciaAntioxidant enzyme gene transfer for ischemic diseases.12/15-Lipoxygenase targets neuronal mitochondria under oxidative stress.Mechanisms of ascorbyl radical formation in human platelet-rich plasma.Significance of brain tissue oxygenation and the arachidonic acid cascade in stroke.Novel insights into the pharmacology of flavonoids.Differential contribution of lipoxygenase isozymes to nigrostriatal vulnerability.Ischemia/Reperfusion.The role of Ca2+ in cell death caused by oxidative glutamate toxicity and ferroptosis.Cardiac 12/15 lipoxygenase-induced inflammation is involved in heart failure.Baicalin Attenuates Blood-Brain Barrier Disruption and Hemorrhagic Transformation and Improves Neurological Outcome in Ischemic Stroke Rats with Delayed t-PA Treatment: Involvement of ONOO--MMP-9 Pathway.Baicalein Promotes Neuronal and Behavioral Recovery After Intracerebral Hemorrhage Via Suppressing Apoptosis, Oxidative Stress and Neuroinflammation.Neuroprotection of taurine through inhibition of 12/15 lipoxygenase pathway in cerebral ischemia of rats.12/15-Lipoxygenase Inhibition or Knockout Reduces Warfarin-Associated Hemorrhagic Transformation After Experimental Stroke.
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Protecting against cerebrovascular injury: contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia.
description
article cientĆfic
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article scientifique
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articolo scientifico
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artigo cientĆfico
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bilimsel makale
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scientific article published on 17 July 2008
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vedeckĆ½ ÄlĆ”nok
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vetenskaplig artikel
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videnskabelig artikel
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vÄdeckĆ½ ÄlĆ”nek
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name
Protecting against cerebrovasc ...... fter transient focal ischemia.
@en
Protecting against cerebrovasc ...... fter transient focal ischemia.
@nl
type
label
Protecting against cerebrovasc ...... fter transient focal ischemia.
@en
Protecting against cerebrovasc ...... fter transient focal ischemia.
@nl
prefLabel
Protecting against cerebrovasc ...... fter transient focal ischemia.
@en
Protecting against cerebrovasc ...... fter transient focal ischemia.
@nl
P2093
P2860
P1433
P1476
Protecting against cerebrovasc ...... fter transient focal ischemia.
@en
P2093
Klaus van Leyen
Monique F Stins
Sophia Wang
Yoshihiro Murata
P2860
P304
P356
10.1161/STROKEAHA.108.514927
P407
P577
2008-07-17T00:00:00Z