Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.
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Clinical and Neurobiological Relevance of Current Animal Models of Autism Spectrum Disorders.PTEN: A master regulator of neuronal structure, function, and plasticityThe potential origin of glioblastoma initiating cellsCollaborative models for translational neuroscience and rehabilitation researchPten deletion causes mTorc1-dependent ectopic neuroblast differentiation without causing uniform migration defects.Excessive activation of mTOR in postnatally generated granule cells is sufficient to cause epilepsy.Cooperativity between MAPK and PI3K signaling activation is required for glioblastoma pathogenesis.PTEN depletion decreases disease severity and modestly prolongs survival in a mouse model of spinal muscular atrophy.REST and CoREST modulate neuronal subtype specification, maturation and maintenance.Pten loss in Olig2 expressing neural progenitor cells and oligodendrocytes leads to interneuron dysplasia and leukodystrophy.Traumatic brain injury reveals novel cell lineage relationships within the subventricular zone.The small GTPases RhoA and Rac1 regulate cerebellar development by controlling cell morphogenesis, migration and foliation.Targets for neural repair therapies after strokeAstrocytic Gq-GPCR-linked IP3R-dependent Ca2+ signaling does not mediate neurovascular coupling in mouse visual cortex in vivo.Gliomagenesis and the use of neural stem cells in brain tumor treatmentIn vivo reprogramming of astrocytes to neuroblasts in the adult brain.In vivo conversion of astrocytes to neurons in the injured adult spinal cordUbiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth.Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner.Maternal inflammation contributes to brain overgrowth and autism-associated behaviors through altered redox signaling in stem and progenitor cells.Multipotent cancer stem cells derived from human malignant peritoneal mesothelioma promote tumorigenesis.Ex vivo neurogenesis within enteric ganglia occurs in a PTEN dependent manner.Cooperativity within and among Pten, p53, and Rb pathways induces high-grade astrocytoma in adult brain.Forebrain neurogenesis after focal Ischemic and traumatic brain injury.Apoptosis regulator through modulating IAP expression (ARIA) controls the PI3K/Akt pathway in endothelial and endothelial progenitor cells.In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics.Hypoxia inducible factor-2α regulates the development of retinal astrocytic network by maintaining adequate supply of astrocyte progenitorsThe PI3K-Akt pathway inhibits senescence and promotes self-renewal of human skin-derived precursors in vitro.The protein phosphatase activity of PTEN is essential for regulating neural stem cell differentiation.Inducible activation of ERK5 MAP kinase enhances adult neurogenesis in the olfactory bulb and improves olfactory function.PTEN regulates retinal interneuron morphogenesis and synaptic layer formation.Current trends in targeted therapies for glioblastoma multiformeIntegrating physiological regulation with stem cell and tissue homeostasisPromoting brain remodeling to aid in stroke recovery.Impacts of phosphatase and tensin homology deleted on chromosome ten (PTEN)-inhibiting chitosan scaffold on growth and differentiation of neural stem cells.Transposon mutagenesis identifies genes that transform neural stem cells into glioma-initiating cells.Neural Stem Cells (NSCs) and ProteomicsMicroRNA-17-92 cluster mediates the proliferation and survival of neural progenitor cells after stroke.Astroglial PTEN Loss Disrupts Neuronal Lamination by Dysregulating Radial Glia-guided Neuronal MigrationFunctional Rescue of Dopaminergic Neuron Loss in Parkinson's Disease Mice After Transplantation of Hematopoietic Stem and Progenitor Cells.
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Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.
@en
Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.
@nl
type
label
Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.
@en
Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.
@nl
prefLabel
Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.
@en
Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.
@nl
P2093
P2860
P1476
Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis
@en
P2093
A Denise Garcia
Caroline Gregorian
Harley I Kornblum
Janel Le Belle
Jonathan Nakashima
Kate Barzan Smith
Michael V Sofroniew
P2860
P304
P356
10.1523/JNEUROSCI.3095-08.2009
P407
P577
2009-02-01T00:00:00Z