A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor.
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The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascadePurification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt actionPurification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitorHepatocyte growth factor activator inhibitor, a novel Kunitz-type serine protease inhibitorExtracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factorScatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptorHepatoma-derived growth factor is involved in lung remodeling by stimulating epithelial growthEvidence for autocrine basis of transformation in NIH-3T3 cells transfected with met/HGF receptor geneNeurotrophic effect of hepatocyte growth factor on central nervous system neurons in vitroGrowth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domainThe tyrosine kinase receptors Ron and Sea control "scattering" and morphogenesis of liver progenitor cells in vitro.c-Kit-kinase induces a cascade of protein tyrosine phosphorylation in normal human melanocytes in response to mast cell growth factor and stimulates mitogen-activated protein kinase but is down-regulated in melanomas.Noncoding mutations of HGF are associated with nonsyndromic hearing loss, DFNB39.Src homology 2-containing inositol 5-phosphatase 1 binds to the multifunctional docking site of c-Met and potentiates hepatocyte growth factor-induced branching tubulogenesis.Hepatocyte growth factor/scatter factor enhances the thrombopoietin mRNA expression in rat hepatocytes and cirrhotic rat livers.Actions of heparin that may affect the malignant process.The role of hepatocyte growth factor and its receptor c-Met in multiple myeloma and other blood malignancies.Development of a highly efficient expression cDNA cloning system: application to oncogene isolation.Disassociation of met-mediated biological responses in vivo: the natural hepatocyte growth factor/scatter factor splice variant NK2 antagonizes growth but facilitates metastasis.Hepatocyte growth factor/scatter factor-induced intracellular signalling.Hepatocyte growth factor (HGF/SF) is expressed in human epithelial cells during embryonic development; studies by in situ hybridisation and northern blot analysis.Cell-specific expression of hepatocyte growth factor in liver. Upregulation in sinusoidal endothelial cells after carbon tetrachloride.Hepatocyte growth factor preferentially activates the anti-inflammatory arm of NF-κB signaling to induce A20 and protect renal proximal tubular epithelial cells from inflammation.Structure-function analysis of hepatocyte growth factor: identification of variants that lack mitogenic activity yet retain high affinity receptor binding.Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the beta-catenin pathway.Keratinocyte growth factor and hepatocyte growth factor/scatter factor are heparin-binding growth factors for alveolar type II cells in fibroblast-conditioned mediumActivation of hepatocyte growth factor in the injured tissues is mediated by hepatocyte growth factor activator.Maintenance of the bronchial alveolar stem cells in an undifferentiated state by secreted frizzled-related protein 1.HGF and MET mutations in primary and secondary lymphedemaHepatocyte growth factor prevents acute renal failure and accelerates renal regeneration in mice.Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells.Role of scatter factor in the pathogenesis of AIDS-related Kaposi sarcoma.Intratracheal instillation of keratinocyte growth factor decreases hyperoxia-induced mortality in rats.Coexpression of hepatocyte growth factor and receptor (Met) in human breast carcinoma.Hepatocyte growth factor and Met receptor expression in human pancreatic carcinogenesisProto-oncogene and growth factor/receptor expression in the establishment of primary human non-small cell lung carcinoma cell lines.Expression of the proto-oncogenes c-met and c-kit and their ligands, hepatocyte growth factor/scatter factor and stem cell factor, in SCLC cell lines and xenograftsThe presence of scatter factor in patients with metastatic spread to the pleuraTransfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene.Hepatocyte growth factor levels in bone marrow plasma of patients with leukaemia and its gene expression in leukaemic blast cells.
P2860
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P2860
A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A broad-spectrum human lung fi ...... t of hepatocyte growth factor.
@en
A broad-spectrum human lung fi ...... t of hepatocyte growth factor.
@nl
type
label
A broad-spectrum human lung fi ...... t of hepatocyte growth factor.
@en
A broad-spectrum human lung fi ...... t of hepatocyte growth factor.
@nl
prefLabel
A broad-spectrum human lung fi ...... t of hepatocyte growth factor.
@en
A broad-spectrum human lung fi ...... t of hepatocyte growth factor.
@nl
P2093
P2860
P356
P1476
A broad-spectrum human lung fi ...... t of hepatocyte growth factor.
@en
P2093
Bottaro DP
Burgess WH
Hirschfield DW
P2860
P304
P356
10.1073/PNAS.88.2.415
P407
P577
1991-01-01T00:00:00Z