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Functionally diverse nucleophilic trapping of iminium intermediates generated utilizing visible lightThe Noscapine Chronicle: A Pharmaco-Historic Biography of the Opiate Alkaloid Family and its Clinical ApplicationsRational design, synthesis, and biological evaluation of third generation α-noscapine analogues as potent tubulin binding anti-cancer agentsA new antiproliferative noscapine analogue: chemical synthesis and biological evaluationAntitumor activity of Noscapine in combination with Doxorubicin in triple negative breast cancer.Radiolabeling, biodistribution and gamma scintigraphy of noscapine hydrochloride in normal and polycystic ovary induced ratsA novel microtubule-modulating agent induces mitochondrially driven caspase-dependent apoptosis via mitotic checkpoint activation in human prostate cancer cells.Novel 9'-substituted-noscapines: synthesis with Suzuki cross-coupling, structure elucidation and biological evaluationA Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine.Non-addictive opium alkaloids selectively induce apoptosis in cancer cells compared to normal cells.Epithelial transport of noscapine across cell monolayer and influence of absorption enhancers on in vitro permeation and bioavailability: implications for intestinal absorption.Optimization of yeast-based production of medicinal protoberberine alkaloids.Metabolic map and bioactivation of the anti-tumour drug noscapine.Engineering biosynthesis of the anticancer alkaloid noscapine in yeast.Characterization of inhibition kinetics of (S)-warfarin hydroxylation by noscapine: implications in warfarin therapy.Apoptosis induction of human endometriotic epithelial and stromal cells by noscapine.Noscapine chemosensitization enhances docetaxel anticancer activity and nanocarrier uptake in triple negative breast cancerOpium induces apoptosis in jurkat cells.Synergistic suppression of noscapine and conventional chemotherapeutics on human glioblastoma cell growth.Peloruside, laulimalide, and noscapine interactions with beta-tubulin.Benzylisoquinoline alkaloid biosynthesis in opium poppy.LC-MS-based metabolomics: an update.Cell death mechanisms of plant-derived anticancer drugs: beyond apoptosis.Carbon-carbon bond cleavage and formation reactions in drug metabolism and the role of metabolic enzymes.Down-regulation of liver-intestine cadherin enhances noscapine-induced apoptosis in human colon cancer cells.Noscapine Increases the Sensitivity of Drug-Resistant Ovarian Cancer Cell Line SKOV3/DDP to Cisplatin by Regulating Cell Cycle and Activating Apoptotic Pathways.'Dopamine-first' mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profileNovel brominated quinoline and pyrimidoquinoline derivatives as potential cytotoxic agents with synergistic effects of γ-radiation.(3R*,5'S*)-6,7-Dimeth-oxy-3-(4'-meth-oxy-6'-methyl-5',6',7',8'-tetra-hydro-1,3-dioxolo[4,5-g]isoquinolin-5'-yl)isobenzofuran-1(3H)-one (racemic α-noscapine).Adlumiceine methyl ester, a new alkaloid from Fumaria vaillantii.Scientific Opinion on the risks for public health related to the presence of opium alkaloids in poppy seedsGreen Routes for the Production of Enantiopure Benzylisoquinoline Alkaloids.Reversal of drug-resistance by noscapine chemo-sensitization in docetaxel resistant triple negative breast cancer.Phytochemical based nanomedicines against cancer: current status and future prospects.Acetylation serves as a protective group in noscapine biosynthesis in opium poppy.Formulation approaches to improving the delivery of an antiviral drug with activity against seasonal flu.Complete biosynthesis of noscapine and halogenated alkaloids in yeast.The effects of promoter variations of the N-Methylcanadine 1-Hydroxylase (CYP82Y1) gene on the noscapine production in opium poppy.Application of Metabolomics in the Study of Natural Products
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The anti-cancer activity of noscapine: a review.
@en
The anti-cancer activity of noscapine: a review.
@nl
type
label
The anti-cancer activity of noscapine: a review.
@en
The anti-cancer activity of noscapine: a review.
@nl
prefLabel
The anti-cancer activity of noscapine: a review.
@en
The anti-cancer activity of noscapine: a review.
@nl
P1476
The anti-cancer activity of noscapine: a review
@en
P2093
Massoud Mahmoudian
P356
10.2174/157489209787002524
P577
2009-01-01T00:00:00Z