Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite.
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Nitric oxide and peroxynitrite in health and diseaseBeneficial effects of n-acetylcysteine on ischaemic brain injuryProtective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusionInhibition of matrix metalloproteinase activity in vivo protects against vascular hyporeactivity in endotoxemia.Contrasting effects of NO and peroxynitrites on HSP70 expression and apoptosis in human monocytes.Time course of nitric oxide synthases, nitrosative stress, and poly(ADP ribosylation) in an ovine sepsis model.Endothelial dysfunction is a potential contributor to multiple organ failure and mortality in aged mice subjected to septic shock: preclinical studies in a murine model of cecal ligation and punctureAngiotensin II-mediated endothelial dysfunction: role of poly(ADP-ribose) polymerase activation.Inhibition of poly(ADP-ribose) synthetase (PARS) and protection against peroxynitrite-induced cytotoxicity by zinc chelation.Endothelial dysfunction in aging animals: the role of poly(ADP-ribose) polymerase activation.Different mechanism of LPS-induced vasodilation in resistance and conductance arteries from SHR and normotensive rats.Excessive stimulation of poly(ADP-ribosyl)ation contributes to endothelial dysfunction in pre-eclampsia.Increased poly(ADP-ribosyl)ation in skeletal muscle tissue of pediatric patients with severe burn injury: prevention by propranolol treatment.Poly(ADP-ribose) polymerase-1 is a key mediator of cisplatin-induced kidney inflammation and injury.Protective effects of relaxin in ischemia/reperfusion-induced intestinal injury due to splanchnic artery occlusion.Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase.The pathogenesis of diabetic complications: the role of DNA injury and poly(ADP-ribose) polymerase activation in peroxynitrite-mediated cytotoxicity.Role of poly(ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme.Anti-inflammatory properties of sirtuin 6 in human umbilical vein endothelial cellsInhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effectsRole of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitorsRole of oxidative stress in experimental sepsis and multisystem organ dysfunction.Catalytic peroxynitrite decomposition improves reperfusion injury after heart transplantation.Red blood cell ATP/ADP & nitric oxide: The best vasodilators in diabetic patients.Therapeutic applications of PARP inhibitors: anticancer therapy and beyondA new, potent poly(ADP-ribose) polymerase inhibitor improves cardiac and vascular dysfunction associated with advanced agingAging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients.Transcription regulation of TNF-alpha-early response genes by poly(ADP-ribose) polymerase-1 in murine heart endothelial cells.Combined neuronal and inducible nitric oxide synthase inhibition in ovine acute lung injurySingle dose treatment with PARP-inhibitor INO-1001 improves aging-associated cardiac and vascular dysfunction.Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction.Inhibition of poly (adenosine diphosphate-ribose) polymerase attenuates lung-kidney crosstalk induced by intratracheal lipopolysaccharide instillation in rats.Inhibition of neuronal nitric oxide synthase in ovine model of acute lung injury.Poly(ADP-ribose) polymerase 1 inhibition protects cardiomyocytes from inflammation and apoptosis in diabetic cardiomyopathy.Role of nitroso radicals as drug targets in circulatory shock.Mechanistic aspects of inducible nitric oxide synthase-induced lung injury in burn trauma.Effects of sulfasalazine on lipid peroxidation and histologic liver damage in a rat model of obstructive jaundice and obstructive jaundice with lipopolysaccharide-induced sepsis.Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging.Potential utility of melatonin as an antioxidant during pregnancy and in the perinatal period.Bench-to-bedside review: sepsis - from the redox point of view.
P2860
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P2860
Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 1997
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Endothelial dysfunction in a r ...... ) synthetase by peroxynitrite.
@en
Endothelial dysfunction in a r ...... ance of the activation of poly
@nl
type
label
Endothelial dysfunction in a r ...... ) synthetase by peroxynitrite.
@en
Endothelial dysfunction in a r ...... ance of the activation of poly
@nl
prefLabel
Endothelial dysfunction in a r ...... ) synthetase by peroxynitrite.
@en
Endothelial dysfunction in a r ...... ance of the activation of poly
@nl
P2093
P2860
P356
P1476
Endothelial dysfunction in a r ...... ) synthetase by peroxynitrite.
@en
P2093
A L Salzman
B Zingarelli
M O'Connor
S Cuzzocrea
P2860
P304
P356
10.1172/JCI119585
P407
P577
1997-08-01T00:00:00Z