Targeted overexpression of IGF-I evokes distinct patterns of organ remodeling in smooth muscle cell tissue beds of transgenic mice.
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The biological actions of dehydroepiandrosterone involves multiple receptorsInsulin-like growth factors in the gastrointestinal tract and liverInsulin-like growth factor system in cancer: novel targeted therapiesInduction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivatorsInsulin-like growth factors and their binding proteins define specific phases of myometrial differentiation during pregnancy in the ratTargeted transgenic expression of beta(2)-adrenergic receptors to type II cells increases alveolar fluid clearanceA modified RMCE-compatible Rosa26 locus for the expression of transgenes from exogenous promotersEndogenous IGF-I and alphaVbeta3 integrin ligands regulate increased smooth muscle hyperplasia in stricturing Crohn's diseaseInsulin-like growth factor-binding protein-5 stimulates growth of human intestinal muscle cells by activation of G{alpha}i3.Gut hormones, and short bowel syndrome: the enigmatic role of glucagon-like peptide-2 in the regulation of intestinal adaptation.YB-1 coordinates vascular smooth muscle alpha-actin gene activation by transforming growth factor beta1 and thrombin during differentiation of human pulmonary myofibroblastsTransgenic overexpression of pregnancy-associated plasma protein-A in murine arterial smooth muscle accelerates atherosclerotic lesion developmentNa(+)-K(+)-ATPase and Ca(2+) clearance proteins in smooth muscle: a functional unit.Smooth muscle cell-specific insulin-like growth factor-1 overexpression in Apoe-/- mice does not alter atherosclerotic plaque burden but increases features of plaque stabilityHuman stanniocalcin-2 exhibits potent growth-suppressive properties in transgenic mice independently of growth hormone and IGFs.Novel diabetic mouse models as tools for investigating diabetic retinopathyEffect of breast milk and weaning on epithelial growth of the small intestine in humans.Myoepithelial cell contraction and milk ejection are impaired in mammary glands of mice lacking smooth muscle alpha-actinEvidence for prostacyclin and cAMP upregulation by bradykinin and insulin-like growth factor 1 in vascular smooth muscle cells.Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury.Detection of epithelial to mesenchymal transition in airways of a bleomycin induced pulmonary fibrosis model derived from an alpha-smooth muscle actin-Cre transgenic mouse.Overexpression of semicarbazide-sensitive amine oxidase in smooth muscle cells leads to an abnormal structure of the aortic elastic laminas.Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular agingSmooth muscle cell signal transduction: implications of vascular biology for vascular surgeons.The emerging role of IGF-1 deficiency in cardiovascular aging: recent advancesComparative endocrinology of aging and longevity regulationGrowth factors in inflammatory bowel disease: the actions and interactions of growth hormone and insulin-like growth factor-I.Increased IGF-IEc expression and mechano-growth factor production in intestinal muscle of fibrostenotic Crohn's disease and smooth muscle hypertrophy.Intestinal mucosal atrophy and adaptationCell-specific effects of insulin receptor substrate-1 deficiency on normal and IGF-I-mediated colon growth.α-Smooth muscle actin is an inconsistent marker of fibroblasts responsible for force-dependent TGFβ activation or collagen production across multiple models of organ fibrosis.Use of an alpha-smooth muscle actin GFP reporter to identify an osteoprogenitor population.Mechanism of strand-specific smooth muscle alpha-actin enhancer interaction by purine-rich element binding protein B (Purbeta).Nuclear degradation of Wilms tumor 1-associating protein and survivin splice variant switching underlie IGF-1-mediated survival.Hepcidin inhibits Smad3 phosphorylation in hepatic stellate cells by impeding ferroportin-mediated regulation of Akt.Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNAMechanical regulation of IGF-I and IGF-binding protein gene transcription in bladder smooth muscle cells.Structure/function analysis of mouse Purbeta, a single-stranded DNA-binding repressor of vascular smooth muscle alpha-actin gene transcription.Dynamic Interplay of Smooth Muscle α-Actin Gene-Regulatory Proteins Reflects the Biological Complexity of Myofibroblast Differentiation.Maintenance of GLUT4 expression in smooth muscle prevents hypertension-induced changes in vascular reactivity.
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Targeted overexpression of IGF-I evokes distinct patterns of organ remodeling in smooth muscle cell tissue beds of transgenic mice.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1997
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Targeted overexpression of IGF ...... issue beds of transgenic mice.
@en
Targeted overexpression of IGF ...... issue beds of transgenic mice.
@nl
type
label
Targeted overexpression of IGF ...... issue beds of transgenic mice.
@en
Targeted overexpression of IGF ...... issue beds of transgenic mice.
@nl
prefLabel
Targeted overexpression of IGF ...... issue beds of transgenic mice.
@en
Targeted overexpression of IGF ...... issue beds of transgenic mice.
@nl
P2093
P2860
P356
P1476
Targeted overexpression of IGF ...... issue beds of transgenic mice.
@en
P2093
S Chernausek
Y Nikiforov
P2860
P304
P356
10.1172/JCI119663
P407
P577
1997-09-01T00:00:00Z