Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines.
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Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory ResponseSyndecan-4 regulates early neutrophil migration and pulmonary inflammation in response to lipopolysaccharide.Transmembrane and extracellular domains of syndecan-1 have distinct functions in regulating lung epithelial migration and adhesion.A disintegrin and metalloproteinase 17 (ADAM17) mediates inflammation-induced shedding of syndecan-1 and -4 by lung epithelial cellsModulation of syndecan-1 shedding after hemorrhagic shock and resuscitation.Syndecan-1 promotes Staphylococcus aureus corneal infection by counteracting neutrophil-mediated host defense.Low molecular weight heparin relieves experimental colitis in mice by downregulating IL-1β and inhibiting syndecan-1 shedding in the intestinal mucosa.Plasma restoration of endothelial glycocalyx in a rodent model of hemorrhagic shock.Heparan sulfate proteoglycans.Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation.Effect of transfusion of fresh frozen plasma on parameters of endothelial condition and inflammatory status in non-bleeding critically ill patients: a prospective substudy of a randomized trial.Shedding of syndecan-1 from human hepatocytes alters very low density lipoprotein clearance.2-O-Sulfated Domains in Syndecan-1 Heparan Sulfate Inhibit Neutrophil Cathelicidin and Promote Staphylococcus aureus Corneal InfectionS-maltoheptaose targets syndecan-bound effectors to reduce smoking-related neutrophilic inflammation.Novel therapeutic targets in the brain tumor microenvironmentSyndecan 1 plays a novel role in enteral glutamine's gut-protective effects of the postischemic gut.Doxycycline impairs neutrophil migration to the airspaces of the lung in mice exposed to intratracheal lipopolysaccharide.Extracellular matrix lumican promotes bacterial phagocytosis, and Lum-/- mice show increased Pseudomonas aeruginosa lung infection severity.Plasma-Mediated Gut Protection After Hemorrhagic Shock is Lessened in Syndecan-1-/- Mice.The endothelial glycocalyx in syndecan-1 deficient mice.Proteoglycans and their roles in brain cancer.Syndecan-1 restitution by plasma after hemorrhagic shock.Gene expression analysis uncovers novel hedgehog interacting protein (HHIP) effects in human bronchial epithelial cellsHeparan Sulfate in the Developing, Healthy, and Injured Lung.Fresh frozen plasma lessens pulmonary endothelial inflammation and hyperpermeability after hemorrhagic shock and is associated with loss of syndecan 1Glycosaminoglycans and infection.Suppressing Syndecan-1 Shedding Ameliorates Intestinal Epithelial Inflammation through Inhibiting NF-κB Pathway and TNF-αSyndecan-2 exerts antifibrotic effects by promoting caveolin-1-mediated transforming growth factor-β receptor I internalization and inhibiting transforming growth factor-β1 signaling.Heparan sulfate: a ubiquitous glycosaminoglycan with multiple roles in immunityExpression of the extracellular sulfatase SULF2 is associated with squamous cell carcinoma of the head and neckCell surface-anchored syndecan-1 ameliorates intestinal inflammation and neutrophil transmigration in ulcerative colitis.Changes of placental syndecan-1 expression in preeclampsia and HELLP syndrome.TLR4 signaling induces TLR3 up-regulation in alveolar macrophages during acute lung injury.Molecular functions of syndecan-1 in disease.Shedding of cell membrane-bound proteoglycans.Matrix metalloproteinase processing of signaling molecules to regulate inflammation.The mercurial nature of neutrophils: still an enigma in ARDS?Syndecans as modulators and potential pharmacological targets in cancer progression.Modulation of endothelial glycocalyx structure under inflammatory conditions.Glycan Activation of a Sheddase: Electrostatic Recognition between Heparin and proMMP-7.
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Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 28 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Syndecan-1 shedding facilitate ...... ng sequestered CXC chemokines.
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Syndecan-1 shedding facilitate ...... ng sequestered CXC chemokines.
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Syndecan-1 shedding facilitate ...... ng sequestered CXC chemokines.
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Syndecan-1 shedding facilitate ...... ng sequestered CXC chemokines.
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Syndecan-1 shedding facilitate ...... ng sequestered CXC chemokines.
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Syndecan-1 shedding facilitate ...... ng sequestered CXC chemokines.
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Syndecan-1 shedding facilitate ...... ng sequestered CXC chemokines.
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Kazutaka Hayashida
Pyong Woo Park
William C Parks
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P304
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10.1182/BLOOD-2009-02-204966
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2009-07-28T00:00:00Z