Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease?
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The role of CCN2 in cartilage and bone developmentConnective tissue growth factor (CCN2, CTGF) and organ fibrosis: lessons from transgenic animalsEyeing the Cyr61/CTGF/NOV (CCN) group of genes in development and diseases: highlights of their structural likenesses and functional dissimilaritiesCutaneous wound healing: recruiting developmental pathways for regenerationTaking aim at the extracellular matrix: CCN proteins as emerging therapeutic targetsInflammatory biomarkers in serum in subjects with and without work related neck/shoulder complaintsIncreased serum and musculotendinous fibrogenic proteins following persistent low-grade inflammation in a rat model of long-term upper extremity overuseTrial by CCN2: a standardized test for fibroproliferative disease?Directed differentiation of skin-derived precursors into fibroblast-like cellsAnti-connective tissue growth factor (CTGF/CCN2) monoclonal antibody attenuates skin fibrosis in mice models of systemic sclerosisThe cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor α-mediated signaling in cancer cells and in cardiomyocytesKey roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiologyInhibition of CTGF ameliorates peritoneal fibrosis through suppression of fibroblast and myofibroblast accumulation and angiogenesisMechanical tension increases CCN2/CTGF expression and proliferation in gingival fibroblasts via a TGFβ-dependent mechanism.Patients with encapsulating peritoneal sclerosis have increased peritoneal expression of connective tissue growth factor (CCN2), transforming growth factor-β1, and vascular endothelial growth factor.Cooperative interaction of CTGF and TGF-β in animal models of fibrotic disease.Transcriptional and post-translational regulation of the quiescence factor and putative tumor suppressor p150(Sal2).TGF-β-stimulated CTGF production enhanced by collagen and associated with biogenesis of a novel 31-kDa CTGF form in human corneal fibroblasts.Elevated transforming growth factor β and mitogen-activated protein kinase pathways mediate fibrotic traits of Dupuytren's disease fibroblastsMatricellular proteins in cardiac adaptation and disease.FosB regulates stretch-induced expression of extracellular matrix proteins in smooth muscle.A shift in the balance of vascular endothelial growth factor and connective tissue growth factor by bevacizumab causes the angiofibrotic switch in proliferative diabetic retinopathy.Tracheal Aspirate Levels of the Matricellular Protein SPARC Predict Development of Bronchopulmonary DysplasiaDexamethasone Stiffens Trabecular Meshwork, Trabecular Meshwork Cells, and MatrixElevation of intraocular pressure in rodents using viral vectors targeting the trabecular meshwork.Connective tissue growth factor regulates retinal neovascularization through p53 protein-dependent transactivation of the matrix metalloproteinase (MMP)-2 geneMatricellular proteins in drug delivery: Therapeutic targets, active agents, and therapeutic localizationVitreous TIMP-1 levels associate with neovascularization and TGF-β2 levels but not with fibrosis in the clinical course of proliferative diabetic retinopathyLPA1-induced cytoskeleton reorganization drives fibrosis through CTGF-dependent fibroblast proliferation.Mechanisms of bronchopulmonary dysplasia.Sphingosine 1-phosphate (S1P) receptor agonists mediate pro-fibrotic responses in normal human lung fibroblasts via S1P2 and S1P3 receptors and Smad-independent signalingGene delivery of TGF-β1 induces arthrofibrosis and chondrometaplasia of synovium in vivo.TGFβ receptor I transactivation mediates stretch-induced Pak1 activation and CTGF upregulation in mesangial cellsTGF-β3 modulates the inflammatory environment and reduces scar formation following vocal fold mucosal injury in rats.Galectin-3 Inhibition by a Small-Molecule Inhibitor Reduces Both Pathological Corneal Neovascularization and Fibrosis.Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases in Inflammation and Fibrosis of Skeletal MusclesActivated alveolar epithelial cells initiate fibrosis through autocrine and paracrine secretion of connective tissue growth factor.Molecular control of vascular development by the matricellular proteins CCN1 (Cyr61) and CCN2 (CTGF).Connective Tissue Growth Factor Promotes Pulmonary Epithelial Cell Senescence and Is Associated with COPD SeverityPossible strategies for anti-fibrotic drug intervention in scleroderma.
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Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease?
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 21 January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Connective tissue growth facto ...... of fibroproliferative disease?
@en
Connective tissue growth facto ...... of fibroproliferative disease?
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type
label
Connective tissue growth facto ...... of fibroproliferative disease?
@en
Connective tissue growth facto ...... of fibroproliferative disease?
@nl
prefLabel
Connective tissue growth facto ...... of fibroproliferative disease?
@en
Connective tissue growth facto ...... of fibroproliferative disease?
@nl
P2093
P2860
P1476
Connective tissue growth facto ...... of fibroproliferative disease?
@en
P2093
Andrew Leask
D J Abraham
Sunil K Parapuram
Xu Shi-Wen
P2860
P2888
P356
10.1007/S12079-009-0037-7
P577
2009-01-21T00:00:00Z