Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene
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Pathogenic triad in COPD: oxidative stress, protease-antiprotease imbalance, and inflammationCandidate genes for COPD: current evidence and researchSystems biology approaches to identify developmental bases for lung diseasesUpdates on the COPD gene listBiomarkers in chronic obstructive pulmonary disease: confusing or useful?Pulmonary-intestinal cross-talk in mucosal inflammatory diseaseGenetics of sputum gene expression in chronic obstructive pulmonary diseaseRisk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstructionPost-GWAS Prioritization Through Data Integration Provides Novel Insights on Chronic Obstructive Pulmonary Disease.Increased iron sequestration in alveolar macrophages in chronic obstructive pulmonary diseasePharmacogenetics of chronic obstructive pulmonary disease: challenges and opportunities.The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study.Impact of a functional polymorphism in the PAR-1 gene promoter in COPD and COPD exacerbationsIntegrative genomics of chronic obstructive pulmonary disease.Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease.Variants in the 15q24/25 locus associate with lung function decline in active smokers.Association of genetic polymorphisms with chronic obstructive pulmonary disease in the Hainan population: a case-control studyOpportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report.Genetic determinants of chronic obstructive pulmonary disease in South Indian male smokers.IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary diseaseImmunology, genetics and microbiota in the COPD pathophysiology: potential scope for patient stratification.Gene susceptibility identification in a longitudinal study confirms new loci in the development of chronic obstructive pulmonary disease and influences lung function decline.Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials.Nicotinic acetylcholine receptor variants associated with susceptibility to chronic obstructive pulmonary disease: a meta-analysis.Recent advances in the genetic epidemiology and molecular genetics of substance use disorders.A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13.Association of IREB2 and CHRNA3 polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiencyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease.Susceptibility loci in lung cancer and COPD: association of IREB2 and FAM13A with pulmonary diseases.Association of cigarette smoking and CRP levels with DNA methylation in α-1 antitrypsin deficiency.CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in Poland.The role of iron in pulmonary pathology.Emerging genetics of COPD.Association of IREB2 Gene rs2568494 Polymorphism with Risk of Chronic Obstructive Pulmonary Disease: A Meta-Analysis.Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice.Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility.Mammalian iron metabolism and its control by iron regulatory proteinsDifferential DNA methylation marks and gene comethylation of COPD in African-Americans with COPD exacerbations
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Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on October 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Integration of genomic and gen ...... as a COPD susceptibility gene
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Integration of genomic and gen ...... as a COPD susceptibility gene.
@nl
type
label
Integration of genomic and gen ...... as a COPD susceptibility gene
@en
Integration of genomic and gen ...... as a COPD susceptibility gene.
@nl
prefLabel
Integration of genomic and gen ...... as a COPD susceptibility gene
@en
Integration of genomic and gen ...... as a COPD susceptibility gene.
@nl
P2093
P2860
P1476
Integration of genomic and gen ...... as a COPD susceptibility gene
@en
P2093
Augustine M K Choi
Christoph Lange
David A Lomas
David Sparrow
Dawn L DeMeo
Edwin K Silverman
Gerard J Criner
Hong P Kim
John Reilly
Raphael Bueno
P2860
P304
P356
10.1016/J.AJHG.2009.09.004
P407
P577
2009-10-01T00:00:00Z