The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor
about
Macrophage metalloelastase, MMP-12, cleaves human apolipoprotein(a) in the linker region between kringles IV-4 and IV-5. Potential relevance to lipoprotein(a) biologyLipoprotein(a) catabolism is regulated by proprotein convertase subtilisin/kexin type 9 through the low density lipoprotein receptorRegulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion developmentA novel peptide derived from human apolipoprotein E is an inhibitor of tumor growth and ocular angiogenesisRegulation of the ligand binding activity of the human very low density lipoprotein receptor by protein kinase C-dependent phosphorylation.Triglyceride Rich Lipoprotein -LPL-VLDL Receptor and Lp(a)-VLDL Receptor Pathways for Macrophage Foam Cell Formation.Abnormal lipoprotein(a) levels predict coronary artery calcification in Southeast Asians but not in Caucasians: use of noninvasive imaging for evaluation of an emerging risk factor.Lipoprotein (a): structure, pathophysiology and clinical implications.Lipoprotein(a): an emerging cardiovascular risk factor.Relationship between lipoprotein (a) and micro/macro complications in type 2 diabetes mellitus: a forgotten targetLipoprotein (a) upregulates ABCA1 in liver cells via scavenger receptor-B1 through its oxidized phospholipidsDissecting mannose 6-phosphate-insulin-like growth factor 2 receptor complexes that control activation and uptake of plasminogen in cells.Lipoprotein(a) metabolism: potential sites for therapeutic targets.PCSK9 inhibition-mediated reduction in Lp(a) with evolocumab: an analysis of 10 clinical trials and the LDL receptor's role.Scavenger receptor-BI is a receptor for lipoprotein(a).Lipoprotein(a): a promising marker for residual cardiovascular risk assessment.PCSK9 targets important for lipid metabolismGenetics of Dyslipidemia and Ischemic Heart Disease.Emerging Therapeutic Options for Lowering of Lipoprotein(a): Implications for Prevention of Cardiovascular Disease.Macrophage-mediated response to hypoxia in disease.Lipoprotein(a): A missing culprit in the management of athero-thrombosis?PCSK9 in context: A contemporary review of an important biological target for the prevention and treatment of atherosclerotic cardiovascular disease.The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor.The low density lipoprotein receptor-related protein modulates protease activity in the brain by mediating the cellular internalization of both neuroserpin and neuroserpin-tissue-type plasminogen activator complexes.The role of O-linked sugars in determining the very low density lipoprotein receptor stability or release from the cell.Roles of the low density lipoprotein receptor and related receptors in inhibition of lipoprotein(a) internalization by proprotein convertase subtilisin/kexin type 9.Lipoprotein (a) as an acute phase reactant in patients on chronic hemodialysis.Galactose-specific asialoglycoprotein receptor is involved in lipoprotein (a) catabolismHDL-C, ABCA1-mediated cholesterol efflux, and lipoprotein(a): insights into a potential novel physiologic role of lipoprotein(a).Lipoprotein(a) hyperlipidemia as cardiovascular risk factor: pathophysiological aspects.Role of various tissues in apo(a) fragmentation and excretion of fragments by the kidney.Effects of simvastatin and carnitine versus simvastatin on lipoprotein(a) and apoprotein(a) in type 2 diabetes mellitus.Lipoprotein [a] is cleared from the plasma primarily by the liver in a process mediated by apolipoprotein [a].Lipoprotein(a) in clinical practice: New perspectives from basic and translational science.
P2860
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P2860
The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
The atherogenic lipoprotein Lp
@nl
The atherogenic lipoprotein Lp ...... mediated by the VLDL receptor
@en
type
label
The atherogenic lipoprotein Lp
@nl
The atherogenic lipoprotein Lp ...... mediated by the VLDL receptor
@en
prefLabel
The atherogenic lipoprotein Lp
@nl
The atherogenic lipoprotein Lp ...... mediated by the VLDL receptor
@en
P2093
P2860
P921
P356
P1476
The atherogenic lipoprotein Lp ...... mediated by the VLDL receptor
@en
P2093
D K Strickland
J T Fallon
K F Kozarsky
K M Argraves
P C Harpel
P2860
P304
P356
10.1172/JCI119753
P407
P577
1997-11-01T00:00:00Z