Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs. - Wikidata - wikimedia - TriplyDB

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs.

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs.

http://www.wikidata.org/entity/Q37374921

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Homing in on the hepatic scar: recent advances in cell-specific targeting of liver fibrosis Non-invasive Markers of Liver Fibrosis: Adjuncts or Alternatives to Liver Biopsy?The myofibroblast in wound healing and fibrosis: answered and unanswered questions Inflammation as a Keystone of Bone Marrow Stroma Alterations in Primary Myelofibrosis Healing scars: targeting pericytes to treat fibrosis Remodelling the extracellular matrix in development and disease Therapeutic targeting of liver inflammation and fibrosis by nanomedicine Extracellular matrix as a contextual determinant of transforming growth factor-β signaling in epithelial-mesenchymal transition and in cancer Cellular and molecular mechanisms in the pathogenesis of liver fibrosis: An update High-yield and high-purity isolation of hepatic stellate cells from normal and fibrotic mouse livers.Myofibroblasts and lung fibrosis induced by carbon nanotube exposure The role of integrins in TGFβ activation in the tumour stroma Targeting Mechanotransduction at the Transcriptional Level: YAP and BRD4 Are Novel Therapeutic Targets for the Reversal of Liver Fibrosis αv integrins: key regulators of tissue fibrosis Strategies and endpoints of antifibrotic drug trials: Summary and recommendations from the AASLD Emerging Trends Conference, Chicago, June 2014.Genetic tools for identifying and manipulating fibroblasts in the mouse Global analysis of glycoproteins identifies markers of endotoxin tolerant monocytes and GPR84 as a modulator of TNFα expression.Molecular magnetic resonance imaging of activated hepatic stellate cells with ultrasmall superparamagnetic iron oxide targeting integrin αvβ₃ for staging liver fibrosis in rat model.Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation.TGF-β activation and function in immunity.Selective measurement of α smooth muscle actin: why β-actin can not be used as a housekeeping gene when tissue fibrosis occurs.Integrins αvβ5 and αvβ3 promote latent TGF-β1 activation by human cardiac fibroblast contraction LAP degradation product reflects plasma kallikrein-dependent TGF-β activation in patients with hepatic fibrosis Integrins as Therapeutic Targets for Respiratory Diseases The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart.The origin of fibrogenic myofibroblasts in fibrotic liver.Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription.Origin of myofibroblasts in the fibrotic liver in mice Human perivascular stem cell-based bone graft substitute induces rat spinal fusion.ABCG2pos lung mesenchymal stem cells are a novel pericyte subpopulation that contributes to fibrotic remodeling.Pericytes at the intersection between tissue regeneration and pathology.Future therapy of portal hypertension in liver cirrhosis - a guess.Pathobiology of liver fibrosis: a translational success story Interleukin-13 Activates Distinct Cellular Pathways Leading to Ductular Reaction, Steatosis, and Fibrosis Thrombin Activates Latent TGFβ1 via Integrin αvβ1 in Gingival Fibroblasts.Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis.Increased expression of p21WAF1/CIP1 in kidney proximal tubules mediates fibrosis.Fibrosis, vascular activation, and immune abnormalities resembling systemic sclerosis in bleomycin-treated Fli-1-haploinsufficient mice Vascular pathobiology in chronic liver disease and cirrhosis - current status and future directions.ACE2 is augmented in dystrophic skeletal muscle and plays a role in decreasing associated fibrosis.

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Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs.

http://www.wikidata.org/entity/Q37374921

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name

Targeting of αv integrin ident ...... es fibrosis in several organs.

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Targeting of αv integrin ident ...... es fibrosis in several organs.

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type

label

Targeting of αv integrin ident ...... es fibrosis in several organs.

@en

Targeting of αv integrin ident ...... es fibrosis in several organs.

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prefLabel

Targeting of αv integrin ident ...... es fibrosis in several organs.

@en

Targeting of αv integrin ident ...... es fibrosis in several organs.

@nl

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Nature Medicine

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Targeting of αv integrin ident ...... es fibrosis in several organs.

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Antonella Pellicoro

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David W Griggs

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Dean Sheppard

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Elisabeth Raschperger

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Jacquelyn J Maher

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John P Iredale

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Joseph H McCarty

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Juan D Rodriguez

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Marilyn M Giacomini

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Michael J Prinsen

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P2860

Galectin-3 regulates myofibroblast activation and hepatic fibrosis

Interactions between growth factors and integrins: latent forms of transforming growth factor-beta are ligands for the integrin alphavbeta1

Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis

Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin

The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-beta1

Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix

Recent developments in myofibroblast biology: paradigms for connective tissue remodeling

Pericytes: developmental, physiological, and pathological perspectives, problems, and promises

Latent TGF-β structure and activation

Integrins: bidirectional, allosteric signaling machines

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10.1038/NM.3282

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12

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2013-11-10T00:00:00Z

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