Protease-resistant form of insulin-like growth factor-binding protein 5 is an inhibitor of insulin-like growth factor-I actions on porcine smooth muscle cells in culture.
about
Substitutions for hydrophobic amino acids in the N-terminal domains of IGFBP-3 and -5 markedly reduce IGF-I binding and alter their biologic actionsPregnancy-associated plasma protein-A2 (PAPP-A2), a novel insulin-like growth factor-binding protein-5 proteinaseInsulin-like growth factor system in cancer: novel targeted therapiesHow matrix metalloproteinases regulate cell behaviorMatrix production and remodeling as therapeutic targets for uterine leiomyomaHuman placental trophoblast as an in vitro model for tumor progression.Engagement of β-arrestin by transactivated insulin-like growth factor receptor is needed for V2 vasopressin receptor-stimulated ERK1/2 activation.The association between integrin-associated protein and SHPS-1 regulates insulin-like growth factor-I receptor signaling in vascular smooth muscle cells.Insulin-like growth factor II signaling in neoplastic proliferation is blocked by transgenic expression of the metalloproteinase inhibitor TIMP-1.Blocking ligand occupancy of the alphaVbeta3 integrin inhibits insulin-like growth factor I signaling in vascular smooth muscle cells.Insulin-like growth factor-binding protein-5 (IGFBP-5): a critical member of the IGF axis.Binding of insulin-like growth factor (IGF)-binding protein-5 to smooth-muscle cell extracellular matrix is a major determinant of the cellular response to IGF-IDisease evidence for IGFBP-2 as a key player in prostate cancer progression and development of osteosclerotic lesions.Insulin-like growth factor binding protein-5 (IGFBP-5) suppresses the tumourigenesis of head and neck squamous cell carcinoma.The in vivo phosphorylation and glycosylation of human insulin-like growth factor-binding protein-5.Substrate specificity of the metalloproteinase pregnancy-associated plasma protein-A (PAPP-A) assessed by mutagenesis and analysis of synthetic peptides: substrate residues distant from the scissile bond are critical for proteolysisPossible involvement of IGF-1 receptor and IGF-binding protein in insulin-induced enhancement of noradrenaline response in diabetic rat aorta.Regulation of insulin-like growth factor I receptor dephosphorylation by SHPS-1 and the tyrosine phosphatase SHP-2.Inhibition of insulin-like growth factor binding protein 5 proteolysis in articular cartilage and joint fluid results in enhanced concentrations of insulin-like growth factor 1 and is associated with improved osteoarthritis.Targeted expression of a protease-resistant IGFBP-4 mutant in smooth muscle of transgenic mice results in IGFBP-4 stabilization and smooth muscle hypotrophy.Proteolysis of insulin-like growth factor binding proteins (IGFBPs) by calpain.Potentiating role of IGFBP-2 on IGF-II-stimulated alkaline phosphatase activity in differentiating osteoblasts.Differential expression and biological effects of insulin-like growth factor-binding protein-4 and -5 in vascular smooth muscle cells.IGF-Binding Proteins: Why Do They Exist and Why Are There So Many?
P2860
Q22253898-74347476-5D7F-458D-A621-058C247EB3B6Q24290962-BDB12B87-18EF-478E-A0FA-82F7B56A0343Q28081603-5892171B-E58D-4F62-B51B-B1EB1ECC837BQ29620360-7E3DC933-3691-4187-8FAD-A44D5A439E0BQ34195881-36B1F416-8880-464B-9CE4-25A8B52FB227Q34588630-C7102E1A-8AB5-4ACD-8930-AE691AFEB03BQ35921791-E36E6A68-AE8F-494E-82F9-E18B739DB7DEQ35973076-D6AB77EB-AE83-4937-ABD6-7A365A911C92Q36301466-1086874E-FFF5-44BA-89FB-1E81C28E566EQ36308611-F31BB516-FD0C-4C24-B464-EB4482925AB9Q36417183-376DC1FC-B8CA-42B0-A5AD-CBB9716404DDQ36904666-624D6319-621F-4B70-A614-599E00A037BDQ37418923-D8AE8634-DCBA-4E8D-A708-341628E05B39Q40034652-5E1F509A-5B81-4714-94F6-5E267BC55DD5Q40133971-7CF559ED-635D-4C04-B3D7-7303541B83BCQ40702779-F81D693F-D45B-4E77-9779-E6E2BE0FACC2Q41817984-E3D04809-3C6F-4C46-A195-C8780144044CQ43847030-5071F18C-F0EE-4C28-80EC-739A0A59D937Q43937867-DDCE3499-B6B8-43A8-8F6F-D05694495D68Q43940100-F8F8D4DF-FF26-4E22-B436-D9D7E9BFE6F7Q46447797-A24A77C3-DD31-4E5C-ABA1-141E9209908BQ47331410-578A8517-B5D6-4187-97B0-A3E1B10FFF8BQ47921690-ED9BCBF4-16E2-4F02-8F1B-9238FA500250Q55259134-7C514450-9D91-456B-A659-10AB4A0D7B48
P2860
Protease-resistant form of insulin-like growth factor-binding protein 5 is an inhibitor of insulin-like growth factor-I actions on porcine smooth muscle cells in culture.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Protease-resistant form of ins ...... mooth muscle cells in culture.
@en
Protease-resistant form of ins ...... mooth muscle cells in culture.
@nl
type
label
Protease-resistant form of ins ...... mooth muscle cells in culture.
@en
Protease-resistant form of ins ...... mooth muscle cells in culture.
@nl
prefLabel
Protease-resistant form of ins ...... mooth muscle cells in culture.
@en
Protease-resistant form of ins ...... mooth muscle cells in culture.
@nl
P2093
P2860
P356
P1476
Protease-resistant form of ins ...... smooth muscle cells in culture
@en
P2093
A J Garmong
D R Clemmons
G D Horwitz
J B Clarke
P2860
P304
P356
10.1172/JCI119803
P407
P50
P577
1997-11-01T00:00:00Z