Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions.
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Monocytes in atherosclerosis: subsets and functionsMacrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen speciesCurrent status of carotid ultrasound in atherosclerosisRole of T-Cell Polarization and Inflammation and Their Modulation by n-3 Fatty Acids in Gestational Diabetes and MacrosomiaRole for Tetrahydrobiopterin in the Fetoplacental Endothelial Dysfunction in Maternal Supraphysiological HypercholesterolemiaHigh-density lipoprotein and 4F peptide reduce systemic inflammation by modulating intestinal oxidized lipid metabolism: novel hypotheses and review of literatureAtherosclerosis in juvenile idiopathic arthritisThe Stereochemistry of trans -4-Hydroxynonenal-Derived Exocyclic 1, N 2 -2′-Deoxyguanosine Adducts Modulates Formation of Interstrand Cross-Links in the 5′-CpG-3′ Sequence †Conformational Interconversion of the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S ) 1, N 2 -Deoxyguanosine Adduct When Mismatched with Deoxyadenosine in DNAFormation of a N 2 -dG: N 2 -dG Carbinolamine DNA Cross-link by the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S ) 1, N 2 -dG AdductReplication Bypass of the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S )-1, N 2 -Deoxyguanosine DNA Adduct by the Sulfolobus solfataricus DNA Polymerase IVC-reactive protein, cardiovascular disease and stroke: new roles for an old biomarkerEffects of an antiatherogenic diet during pregnancy on markers of maternal and fetal endothelial activation and inflammation: the CARRDIP studyNatural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunityMitogenic responses of vascular smooth muscle cells to lipid peroxidation-derived aldehyde 4-hydroxy-trans-2-nonenal (HNE): role of aldose reductase-catalyzed reduction of the HNE-glutathione conjugates in regulating cell growthEthnic differences in maternal total cholesterol and triglyceride levels during pregnancy: the contribution of demographics, behavioural factors and clinical characteristics.Monocyte recruitment during infection and inflammationLingering prenatal effects of the 1918 influenza pandemic on cardiovascular disease.Physical training and metabolic supplementation reduce spontaneous atherosclerotic plaque rupture and prolong survival in hypercholesterolemic mice.A-002 (Varespladib), a phospholipase A2 inhibitor, reduces atherosclerosis in guinea pigs.Childhood obesity: a life-long health risk4-Hydroxynonenal Contributes to Angiogenesis through a Redox-Dependent Sphingolipid Pathway: Prevention by Hydralazine Derivatives.Prenatal exposure to apoE deficiency and postnatal hypercholesterolemia are associated with altered cell-specific lysine methyltransferase and histone methylation patterns in the vasculature.Metabolic syndrome: from epidemiology to systems biology.Effect of maternal cardiovascular conditions and risk factors on offspring cardiovascular diseaseReproducibility of aortic intima-media thickness in infants using edge-detection software and manual caliper measurementsPlacental ABCA1 Expression Is Increased in Spontaneous Preterm Deliveries Compared with Iatrogenic Preterm Deliveries and Term Deliveries.The relationship of hydroxyeicosatetraenoic acids and F2-isoprostanes to plaque instability in human carotid atherosclerosisOvernutrition and maternal obesity in sheep pregnancy alter the JNK-IRS-1 signaling cascades and cardiac function in the fetal heart.Modified LDL - trigger of atherosclerosis and inflammation in the arterial intima.Intrauterine nutrition: long-term consequences for vascular health.Immune recognition of OxLDL in atherosclerosis.Abnormal microvascular reactivity with hypercholesterolaemia in pregnancy.Maternal obesity and high-fat diet program offspring metabolic syndrome.Chronic treatment with nitric oxide-releasing aspirin reduces plasma low-density lipoprotein oxidation and oxidative stress, arterial oxidation-specific epitopes, and atherogenesis in hypercholesterolemic miceBaboon fetal arterial endothelial cells are more responsive to challenge by tumor necrosis factor α (TNF-α) than baboon fetal umbilical vein endothelial cells.Early onset intrauterine growth restriction in a mouse model of gestational hypercholesterolemia and atherosclerosisBeneficial effects of antioxidants and L-arginine on oxidation-sensitive gene expression and endothelial NO synthase activity at sites of disturbed shear stress.Atherogenic factors and their epigenetic relationshipsFamilial hypercholesterolaemia in Finland: common, rare and mild mutations of the LDL receptor and their clinical consequences. Finnish FH-group.
P2860
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P2860
Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1997
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Fatty streak formation occurs ...... early atherosclerotic lesions.
@en
Fatty streak formation occurs ...... early atherosclerotic lesions.
@nl
type
label
Fatty streak formation occurs ...... early atherosclerotic lesions.
@en
Fatty streak formation occurs ...... early atherosclerotic lesions.
@nl
prefLabel
Fatty streak formation occurs ...... early atherosclerotic lesions.
@en
Fatty streak formation occurs ...... early atherosclerotic lesions.
@nl
P2093
P2860
P921
P356
P1476
Fatty streak formation occurs ...... early atherosclerotic lesions.
@en
P2093
A Postiglione
F P D'Armiento
F P Mancini
J L Witztum
W Palinski
P2860
P304
P356
10.1172/JCI119813
P407
P577
1997-12-01T00:00:00Z