Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor.
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Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor II receptor contributes to T cell activationResidues essential for plasminogen binding by the cation-independent mannose 6-phosphate receptorBinding of urokinase-type plasminogen activator receptor (uPAR) to the mannose 6-phosphate/insulin-like growth factor II receptor: contrasting interactions of full-length and soluble forms of uPARA human keratinocyte cell line produces two autocrine growth inhibitors, transforming growth factor-beta and insulin-like growth factor binding protein-6, in a calcium- and cell density-dependent mannerThe latent transforming growth factor beta binding protein (LTBP) familyThe crystal structure of CREG, a secreted glycoprotein involved in cellular growth and differentiationInteractions between growth factors and integrins: latent forms of transforming growth factor-beta are ligands for the integrin alphavbeta1Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding proteinThrombospondin causes activation of latent transforming growth factor-beta secreted by endothelial cells by a novel mechanismMannose 6-phosphate/insulin-like growth factor-II receptor targets the urokinase receptor to lysosomes via a novel binding interactionLatent transforming growth factor-beta binding protein domains involved in activation and transglutaminase-dependent cross-linking of latent transforming growth factor-betaDecreased expression of the mannose 6-phosphate/insulin-like growth factor-II receptor promotes growth of human breast cancer cellsDown-regulation of the M6P/IGF-II receptor increases cell proliferation and reduces apoptosis in neonatal rat cardiac myocytesSomatic frameshift mutations in the Bloom syndrome BLM gene are frequent in sporadic gastric carcinomas with microsatellite mutator phenotypeEvasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.Structure of a functional IGF2R fragment determined from the anomalous scattering of sulfur.Mannose 6-phosphate receptors: new twists in the taleHealing of burn wounds in transgenic mice overexpressing transforming growth factor-beta 1 in the epidermisCyclical strain modulates metalloprotease and matrix gene expression in human tenocytes via activation of TGFβExtracellular fibrillar structure of latent TGF beta binding protein-1: role in TGF beta-dependent endothelial-mesenchymal transformation during endocardial cushion tissue formation in mouse embryonic heartReduction of tendon adhesions following administration of Adaprev, a hypertonic solution of mannose-6-phosphate: mechanism of action studiesRetinoic acid alters the intracellular trafficking of the mannose-6-phosphate/insulin-like growth factor II receptor and lysosomal enzymesHigh-affinity prorenin binding to cardiac man-6-P/IGF-II receptors precedes proteolytic activation to reninTargeting activated hepatic stellate cells (aHSCs) for liver fibrosis imagingLocalization of the binding site for transforming growth factor-beta in human alpha2-macroglobulin to a 20-kDa peptide that also contains the bait region.Autocrine expression of activated transforming growth factor-beta(1) induces apoptosis in normal rat liver.Loss of heterozygosity of M6P/IGF2R gene is an early event in the development of prostate cancer.B-vitamin and homocysteine status determines ovarian response to gonadotropin treatment in sheepMannose-6-phosphate/insulin-like growth factor-II receptor is a receptor for retinoic acid.Targeting TGFβ signaling in subchondral bone and articular cartilage homeostasisRole of cytokines in the pathogenesis of posterior capsule opacification.Cell-cell signaling between adult rat ventricular myocytes and cardiac microvascular endothelial cells in heterotypic primary culture.Targeting insulin-like growth factor axis in hepatocellular carcinoma.Differential expression of insulin-like growth factors I and II (IGF I and II), mRNA, peptide and binding protein 1 during mouse palate development: comparison with TGF beta peptide distributionThe secreted glycoprotein CREG inhibits cell growth dependent on the mannose-6-phosphate/insulin-like growth factor II receptor.IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomas.Expression of insulin-like growth factor 2 receptor in corneal keratocytes during differentiation and in response to wound healingMannose metabolism: more than meets the eye.Molecular carcinogenesis of hepatocellular carcinoma and intrahepatic cholangiocarcinoma: one step closer to personalized medicine?The role of TGFβ1 and LRG1 in cardiac remodelling and heart failure.
P2860
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P2860
Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Cellular activation of latent ...... rowth factor type II receptor.
@en
Cellular activation of latent ...... rowth factor type II receptor.
@nl
type
label
Cellular activation of latent ...... rowth factor type II receptor.
@en
Cellular activation of latent ...... rowth factor type II receptor.
@nl
prefLabel
Cellular activation of latent ...... rowth factor type II receptor.
@en
Cellular activation of latent ...... rowth factor type II receptor.
@nl
P2860
P356
P1476
Cellular activation of latent ...... rowth factor type II receptor.
@en
P2093
D B Rifkin
P A Dennis
P2860
P304
P356
10.1073/PNAS.88.2.580
P407
P577
1991-01-01T00:00:00Z