Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design? - Wikidata - wikimedia - TriplyDB

Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?

Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?

http://www.wikidata.org/entity/Q37377502

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Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals Association between variants of the leptin receptor gene (LEPR) and overweight: a systematic review and an analysis of the CoLaus study The influence of clinical and genetic factors on the development of obesity in children with type 1 diabetes.Genetic association of left ventricular mass assessed by M-mode and two-dimensional echocardiography.The INSIG2 rs7566605 polymorphism is not associated with body mass index and breast cancer risk.Mutation screen and association studies for the fatty acid amide hydrolase (FAAH) gene and early onset and adult obesity.From monogenic to polygenic obesity: recent advances.Common Genetic Variant of insig2 Gene rs7566605 Polymorphism Is Associated with Severe Obesity in North India Meta-analysis of sequencing studies with heterogeneous genetic associations Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.Association of the European lactase persistence variant (LCT-13910 C>T polymorphism) with obesity in the Canary Islands.Tuberculosis as a complex trait: impact of genetic epidemiological study design Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level.Gender-Specific Effect of -102G>A Polymorphism in Insulin Induced Gene 2 on Obesity in Chinese Children.Meta-analysis in clinical trials revisited Impact of phenotype definition on genome-wide association signals: empirical evaluation in human immunodeficiency virus type 1 infection.INSIG2 variants, dietary patterns and metabolic risk in Samoa Findings from the Quebec Family Study on the Etiology of Obesity: Genetics and Environmental Highlights.Challenges in reproducibility of genetic association studies: lessons learned from the obesity field.Meta-analysis methods for genome-wide association studies and beyond.The future of nutrition: Nutrigenomics and nutrigenetics in obesity and cardiovascular diseases.Impact of home visit capacity on genetic association studies of late-onset Alzheimer's disease.FTO and INSIG2 Genotyping Combined with Metabolic and Anthropometric Phenotyping of Morbidly Obese Patients Association between intramuscular fat in the arm following arm training and INSIG2.Multilocus analyses of seven candidate genes suggest interacting pathways for obesity-related traits in Brazilian populations.INSIG2 polymorphism and weight gain, dyslipidemia and serum adiponectin in Finnish patients with schizophrenia treated with clozapine.Sex-specific effects of weight-affecting gene variants in a life course perspective--The HUNT Study, Norway.Two candidate genes (FTO and INSIG2) for fat accumulation in four canids: chromosome mapping, gene polymorphisms and association studies of body and skin weight of red foxes.High allelic burden of four obesity SNPs is associated with poorer weight loss outcomes following gastric bypass surgery.Alzheimer's Disease Sequencing Project discovery and replication criteria for cases and controls: Data from a community-based prospective cohort study with autopsy follow-up.Ovine insulin induced-gene-2: molecular characterization, polymorphisms and association with milk traits.

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Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?

http://www.wikidata.org/entity/Q37377502

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 23 October 2009

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

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JOURNAL.PGEN.1000694

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Meta-analysis of the INSIG2 as ...... imates relate to study design?

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Andreas Luchner

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Anita Suk

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Barbara Kollerits

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Bernhard Paulweber

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Birgit Langer

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Christian Dina

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Christoph Lange

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David Meyre

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Dawn Waterworth

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Dieter Rosskopf

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P2860

The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis

Meta-analysis in clinical trials

Thermally oxidized oil increases the expression of insulin-induced genes and inhibits activation of sterol regulatory element-binding protein-2 in rat liver

Genome-wide association scans identified CTNNBL1 as a novel gene for obesity.

Association between the -455T>C promoter polymorphism of the APOC3 gene and the metabolic syndrome in a multi-ethnic sample

Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes

INSIG2 gene polymorphism is associated with increased subcutaneous fat in women and poor response to resistance training in men.

No association between microsomal triglyceride transfer protein (MTP) haplotype and longevity in humans

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e1000694

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scholarly article

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10.1371/JOURNAL.PGEN.1000694

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10

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5

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Florian Kronenberg

Gudmar Thorleifsson

Marjo-Riitta Järvelin

Unnur Þorsteinsdóttir

Marika Kaakinen

Claude Bouchard

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2009-10-23T00:00:00Z

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38030954

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19851442

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