Complement factor H-derived short consensus repeat 18-20 enhanced complement-dependent cytotoxicity of ofatumumab on chronic lymphocytic leukemia cells.

Complement factor H-derived short consensus repeat 18-20 enhanced complement-dependent cytotoxicity of ofatumumab on chronic lymphocytic leukemia cells.

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http://www.wikidata.org/entity/Q37377923
Enhanced CDC of B cell chronic lymphocytic leukemia cells mediated by rituximab combined with a novel anti-complement factor H antibodyNeutralization of membrane complement regulators improves complement-dependent effector functions of therapeutic anticancer antibodies targeting leukemic cells.Ofatumumab as front-line therapy in untreated chronic lymphocytic leukemia.Regulation of complement and modulation of its activity in monoclonal antibody therapy of cancer.Monoclonal Antibodies in Cancer Therapy: Mechanisms, Successes and Limitations.Ofatumumab in the treatment of non-Hodgkin's lymphomas.Targeted delivery of siRNA using transferrin-coupled lipoplexes specifically sensitizes CD71 high expressing malignant cells to antibody-mediated complement attack.Novel bifunctional single-chain variable antibody fragments to enhance virolysis by complement: generation and proof-of-concept.Resistance to complement activation, cell membrane hypersialylation and relapses in chronic lymphocytic leukemia patients treated with rituximab and chemotherapy
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Complement factor H-derived short consensus repeat 18-20 enhanced complement-dependent cytotoxicity of ofatumumab on chronic lymphocytic leukemia cells.

Item
http://www.wikidata.org/entity/Q37377923
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Complement factor H-derived sh ...... ic lymphocytic leukemia cells.
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Complement factor H-derived sh ...... ic lymphocytic leukemia cells.
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type
label
Complement factor H-derived sh ...... ic lymphocytic leukemia cells.
@en
Complement factor H-derived sh ...... ic lymphocytic leukemia cells.
@nl
prefLabel
Complement factor H-derived sh ...... ic lymphocytic leukemia cells.
@en
Complement factor H-derived sh ...... ic lymphocytic leukemia cells.
@nl
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Complement factor H-derived sh ...... ic lymphocytic leukemia cells.
@en
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P2860
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P31
P356
10.3324/HAEMATOL.2013.089615
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P577
P698
P921
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