Insights into the substrate specificity, inhibitors, regulation, and polymorphisms and the clinical impact of human cytochrome P450 1A2. - Wikidata - wikimedia - TriplyDB

Insights into the substrate specificity, inhibitors, regulation, and polymorphisms and the clinical impact of human cytochrome P450 1A2.

Insights into the substrate specificity, inhibitors, regulation, and polymorphisms and the clinical impact of human cytochrome P450 1A2.

http://www.wikidata.org/entity/Q37378059

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Pharmacological approaches to the challenge of treatment-resistant depression Human Cytochrome P450 1A1 Structure and Utility in Understanding Drug and Xenobiotic Metabolism Cytochrome P450 1A2 Metabolizes 17β-Estradiol to Suppress Hepatocellular Carcinoma Computational and in vitro studies on the inhibitory effects of herbal compounds on human cytochrome P450 1A2.Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2.CYP1A2 polymorphism -1545C > T (rs2470890) is associated with increased side effects to clozapine.Phospholipase D: enzymology, functionality, and chemical modulation PharmGKB summary: very important pharmacogene information for CYP1A2.CYP1A2--a novel genetic marker for early aromatase inhibitor response in the treatment of breast cancer patients Caffeine Cytochrome P450 1A2 Metabolic Phenotype Does Not Predict the Metabolism of Heterocyclic Aromatic Amines in Humans.Population pharmacokinetics of dolutegravir in HIV-infected treatment-naive patients.The Impact of CYP1A2 and CYP2E1 Genes Polymorphism on Theophylline Response Development and validation of an HPLC-UV method for the simultaneous determination of the antipsychotics clozapine, olanzapine and quetiapine, several beta-blockers and their metabolites.Selective Inhibition of Bakuchicin Isolated from Psoralea corylifolia on CYP1A in Human Liver Microsomes Extreme sensitivity and the practical implications of risk assessment thresholds.Gene expression and immunochemical localization of major cytochrome P450 drug-metabolizing enzymes in bovine nasal olfactory and respiratory mucosa.Proper heat shock pretreatment reduces acute liver injury induced by carbon tetrachloride and accelerates liver repair in mice.A Comparison of the In Vitro Inhibitory Effects of Thelephoric Acid and SKF-525A on Human Cytochrome P450 Activity.In vitro analysis of factors influencing CYP1A2 expression as potential determinants of interindividual variation.Gene polymorphisms involved in triptans pharmacokinetics and pharmacodynamics in migraine therapy.Factors affecting interindividual differences in clozapine response: a review and case report.Substrate selectivity of drug-metabolizing cytochrome P450s predicted from crystal structures and in silico modeling.Cytochrome P450 variations in different ethnic populations.Challenges in exploring the cytochrome P450 system as a source of variation in canine drug pharmacokinetics.Pharmacogenomics of anti-platelet and anti-coagulation therapy.Female gender as a susceptibility factor for drug-induced liver injury.Blood pressure in relation to coffee and caffeine consumption.Oral antineoplastic agent interactions with medicinal plants and food: an issue to take into account.Combination analysis in genetic polymorphisms of drug-metabolizing enzymes CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A5 in the Japanese population.Lack of effect of smoking status on axitinib pharmacokinetics in patients with non-small-cell lung cancer.Systematical analysis of impacts of heat stress on the proliferation, apoptosis and metabolism of mouse hepatocyte.Quantitative Prediction of Drug Interactions Caused by CYP1A2 Inhibitors and Inducers.Co-expression of active human cytochrome P450 1A2 and cytochrome P450 reductase on the cell surface of Escherichia coli.Does "smoker's paradox" exist in clopidogrel-treated Turkish patients with acute coronary syndrome.Impact of smoking status on clinical outcomes after successful chronic total occlusion intervention: Korean national registry of CTO intervention.The genetic profiles of CYP1A1, CYP1A2 and CYP2E1 enzymes as susceptibility factor in xenobiotic toxicity in Turkish population.Genetic polymorphisms of cytochrome P450-1A2 (CYP1A2) among Emiratis Genetic polymorphism analysis of the drug-metabolizing enzyme CYP1A2 in a Uyghur Chinese population: a pilot study.Metabolism of the anthelmintic drug niclosamide by cytochrome P450 enzymes and UDP-glucuronosyltransferases: metabolite elucidation and main contributions from CYP1A2 and UGT1A1.The expression, induction and pharmacological activity of CYP1A2 are post-transcriptionally regulated by microRNA hsa-miR-132-5p.

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Insights into the substrate specificity, inhibitors, regulation, and polymorphisms and the clinical impact of human cytochrome P450 1A2.

http://www.wikidata.org/entity/Q37378059

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

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scientific article published on 10 July 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Insights into the substrate sp ...... of human cytochrome P450 1A2.

@en

Insights into the substrate sp ...... of human cytochrome P450 1A2.

@nl

type

label

Insights into the substrate sp ...... of human cytochrome P450 1A2.

@en

Insights into the substrate sp ...... of human cytochrome P450 1A2.

@nl

prefLabel

Insights into the substrate sp ...... of human cytochrome P450 1A2.

@en

Insights into the substrate sp ...... of human cytochrome P450 1A2.

@nl

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S12248-009-9127-Y

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The AAPS Journal

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Insights into the substrate sp ...... of human cytochrome P450 1A2.

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Eli Chan

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Li-Ping Yang

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Shu-Feng Zhou

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Ya-He Liu

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Zhi-Wei Zhou

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CYP1A induction and human risk assessment: an evolving tale of in vitro and in vivo studies

Human enzymes involved in the metabolic activation of carcinogenic aristolochic acids: evidence for reductive activation by cytochromes P450 1A1 and 1A2

Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2

Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen

Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo

Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor

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Human CYP1A2: sequence, gene structure, comparison with the mouse and rat orthologous gene, and differences in liver 1A2 mRNA expression

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Human P(3)450: cDNA and complete protein sequence, repetitive Alu sequences in the 3' nontranslated region, and localization of gene to chromosome 15

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1004902101

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