about
The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting stepHuntingtin-interacting protein 1 (Hip1) and Hip1-related protein (Hip1R) bind the conserved sequence of clathrin light chains and thereby influence clathrin assembly in vitro and actin distribution in vivoA role for the CHC22 clathrin heavy-chain isoform in human glucose metabolismSelf-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathwayClathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regenerationAdaptor self-aggregation, adaptor-receptor recognition and binding of alpha-adaptin subunits to the plasma membrane contribute to recruitment of adaptor (AP2) components of clathrin-coated pitsInteractions of NK cell receptor KIR3DL1*004 with chaperones and conformation-specific antibody reveal a functional folded state as well as predominant intracellular retentionHeparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seedsClathrin self-assembly involves coordinated weak interactions favorable for cellular regulationEndocytosis regulates cell soma translocation and the distribution of adhesion proteins in migrating neuronsAccommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domainConformation Switching of Clathrin Light Chain Regulates Clathrin Lattice AssemblyThe adaptor protein GULP promotes Jedi-1-mediated phagocytosis through a clathrin-dependent mechanismClathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOGA common clathrin-mediated machinery co-ordinates cell-cell adhesion and bacterial internalizationClathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration.Actin scaffolding by clathrin heavy chain is required for skeletal muscle sarcomere organization.Dimorphic motifs in D0 and D1+D2 domains of killer cell Ig-like receptor 3DL1 combine to form receptors with high, moderate, and no avidity for the complex of a peptide derived from HIV and HLA-A*2402.Plasticity of B cell receptor internalization upon conditional depletion of clathrinClathrin heavy and light chain isoforms originated by independent mechanisms of gene duplication during chordate evolution.Comparison of the primary structures of clathrin light chains from bovine brain and adrenal gland by peptide mapping.Clathrin hub expression affects early endosome distribution with minimal impact on receptor sorting and recycling.Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cellsThe B lymphocyte adaptor molecule of 32 kilodaltons (Bam32) regulates B cell antigen receptor internalization.Clathrin light and heavy chain interface: alpha-helix binding superhelix loops via critical tryptophans.Novel binding sites on clathrin and adaptors regulate distinct aspects of coat assembly.Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission.The CHC22 clathrin-GLUT4 transport pathway contributes to skeletal muscle regeneration.Clathrin phosphorylation is required for actin recruitment at sites of bacterial adhesion and internalization.Antigen processing and presentation: close encounters in the endocytic pathway.Membrane traffic in skeletal muscle.New faces of the familiar clathrin lattice.A Distinctive Cytoplasmic Tail Contributes to Low Surface Expression and Intracellular Retention of the Patr-AL MHC Class I MoleculeTropomyosin-like properties of clathrin light chains allow a rapid, high-yield purification.ADP-ribosylation factor 6 and endocytosis at the apical surface of Madin-Darby canine kidney cellsT cell receptor engagement leads to phosphorylation of clathrin heavy chain during receptor internalization.TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis.100-kD proteins of Golgi- and trans-Golgi network-associated coated vesicles have related but distinct membrane binding propertiesAnisotropic nanocrystal arrays organized on protein lattices formed by recombinant clathrin fragments.Clathrin light chains' role in selective endocytosis influences antibody isotype switching
P50
Q24294707-3206B95E-0A40-4F4E-A8A4-45BA9EA74D70Q24313078-8B6BFFFF-255A-45F2-B561-860E7B9E3FFBQ24314921-23D322FD-4A66-4089-9DC0-DEB0E7CCB3B9Q24339502-581F8443-6E7D-47F6-8251-C0B9FD202138Q24561598-9F5B57DC-A507-4E43-B973-D440A6613931Q24564624-15FC1670-1D2E-4CB1-9C5F-F9F2D1B13869Q24598715-206CD043-E149-4957-A967-235D1AA87E6FQ24630644-9FEF9E3B-3DD7-47AA-B818-EBEFA3868B4DQ24672270-FDC6C99F-6E8E-47BE-AF95-5605DBF3FFBDQ27349866-E027A786-C334-4E2F-8E6E-70DCF5CA86BAQ27660034-59EF0EC2-BF1A-42DC-981F-B79C74181335Q27661768-69D99BD2-CAD1-4961-9C9F-F88072523F1EQ30411126-D8AE441C-7D92-47B2-87F9-75EE91BD5D2CQ30528931-BBC3D4F4-BC3F-445F-9E80-79BAC57B048FQ30543960-E1AA87E6-A597-44D2-A7F8-AEAACC339D69Q30580241-05E740C2-BE4B-47E3-BEAA-1E66491131B3Q33601446-50276171-C74B-4A22-BD1A-8E08A40C689EQ33682888-88C5323A-EE1E-4456-A11D-D7F4822FBE48Q33768505-CB839CCA-116C-4240-B2FE-7A037EBEE0D6Q33780768-707B4D90-58E4-418B-BFD9-E551E4EA8D62Q33939702-15479443-ABE0-4C36-9364-AA92150FA958Q33946749-29ABB488-794E-46CE-9A23-9A971B1B1EF8Q34098170-3D97178A-7166-4AF2-8ED8-5455927DFF7CQ34360396-D97F1D66-ED31-4271-9250-61907436AC92Q34369757-B5CF3029-2185-4CD1-93CC-EBDF9863B271Q34575289-DC4E65E0-31BE-47D3-A416-A20D4C992282Q34735674-6693F431-6A03-4603-9791-688F84CC6948Q35035622-04E23587-5F77-4E69-BF9A-9D75D1174D4CQ35503765-41E13B24-608F-4574-BE20-B9CF3B67E230Q35633056-D4E40657-634E-43BE-9887-7EBBDA594212Q35746740-419D0EB8-F635-4D27-843B-8D2BC191F1F6Q36063947-0C58C402-DEEE-43DF-B5C4-CEB809E401A6Q36119419-16D85C49-6C38-402F-905D-42662D284761Q36207147-EA1DADD3-2E3C-4DBB-B0D6-9F0F50A4CA6BQ36310716-DEDE01DE-CB4E-4C3B-812C-8095EC433CA2Q36399415-747B8599-347A-4640-B73A-96BCE57545A8Q36403570-D61ADB53-EA25-4A81-A4C1-7C44F409FCF4Q36531520-CDB0EFA9-EC80-4208-9136-6A68540C3E8CQ36985425-24BC1A83-2576-49FA-8988-BD9E4FB19FF2Q37258468-F36A9FC1-9BF1-4046-804D-85AB3CBF1079
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Frances M Brodsky
@ast
Frances M Brodsky
@en
Frances M Brodsky
@es
Frances M Brodsky
@nl
Frances M Brodsky
@sl
type
label
Frances M Brodsky
@ast
Frances M Brodsky
@en
Frances M Brodsky
@es
Frances M Brodsky
@nl
Frances M Brodsky
@sl
prefLabel
Frances M Brodsky
@ast
Frances M Brodsky
@en
Frances M Brodsky
@es
Frances M Brodsky
@nl
Frances M Brodsky
@sl
P106
P21
P31
P496
0000-0002-1334-9258