Na-K-2Cl cotransporter gene expression and function during enterocyte differentiation. Modulation of Cl- secretory capacity by butyrate
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Cloning, characterization, and chromosomal location of a novel human K+-Cl- cotransporterDisruption of the K+ channel beta-subunit KCNE3 reveals an important role in intestinal and tracheal Cl- transportDab2, megalin, cubilin and amnionless receptor complex might mediate intestinal endocytosis in the suckling ratRat small intestine expresses the reelin-Disabled-1 signalling pathwayCation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)Phorbol 12-myristate 13-acetate-induced endocytosis of the Na-K-2Cl cotransporter in MDCK cells is associated with a clathrin-dependent pathwayTransient vs. prolonged histone hyperacetylation: effects on colon cancer cell growth, differentiation, and apoptosis.Coordinate down-regulation of adenylyl cyclase isoforms and the stimulatory G protein (G(s)) in intestinal epithelial cell differentiation.Expression, localization, and functional evaluation of CFTR in bovine corneal endothelial cellsActivated PKC{delta} and PKC{epsilon} inhibit epithelial chloride secretion response to cAMP via inducing internalization of the Na+-K+-2Cl- cotransporter NKCC1Physiological relevance of cell-specific distribution patterns of CFTR, NKCC1, NBCe1, and NHE3 along the crypt-villus axis in the intestine.Rescuing protein conformation: prospects for pharmacological therapy in cystic fibrosisSalmonella infection induces a hypersecretory phenotype in human intestinal xenografts by inducing cyclooxygenase 2.Localization and vasopressin regulation of the Na⁺-K⁺-2Cl⁻ cotransporter in the distal colonic epithelium.Toward the pharmacogenomics of cystic fibrosis--an update.Spontaneous development of intestinal and colonic atrophy and inflammation in the carnitine-deficient jvs (OCTN2(-/-)) miceTransport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+)KLF4 regulation in intestinal epithelial cell maturationDeveloping novel antisecretory drugs to treat infectious diarrhea.Upregulation of basolateral small conductance potassium channels (KCNQ1/KCNE3) in ulcerative colitis.Chloride-led disruption of the intestinal mucous layer impedes Salmonella invasion: evidence for an 'enteric tear' mechanism.Induction of Na+/K+/2Cl- cotransporter expression mediates chronic potentiation of intestinal epithelial Cl- secretion by EGF.Inhibition of epithelial chloride secretion by butyrate: role of reduced adenylyl cyclase expression and activity.Phosphatidylinositol 3-kinase-dependent pathways oppose Fas-induced apoptosis and limit chloride secretion in human intestinal epithelial cells. Implications for inflammatory diarrheal states.CFTR upregulates the expression of the basolateral Na(+)-K(+)-2Cl(-) cotransporter in cultured pancreatic duct cells.PBA increases CFTR expression but at high doses inhibits Cl(-) secretion in Calu-3 airway epithelial cells.Butyrate increases apical membrane CFTR but reduces chloride secretion in MDCK cells.Activation of the Na-K-Cl cotransporter NKCC1 detected with a phospho-specific antibody.SCFA increase intestinal Na absorption by induction of NHE3 in rat colon and human intestinal C2/bbe cells.Effects of butyrate on active sodium and chloride transport in rat and rabbit distal colon.Apical NHE isoforms differentially regulate butyrate-stimulated Na absorption in rat distal colon.Repression of MUC2 gene expression by butyrate, a physiological regulator of intestinal cell maturation.Thiazide-sensitive NaCl-cotransporter in the intestine: possible role of hydrochlorothiazide in the intestinal Ca2+ uptake.
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P2860
Na-K-2Cl cotransporter gene expression and function during enterocyte differentiation. Modulation of Cl- secretory capacity by butyrate
description
article científic
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article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1998
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Na-K-2Cl cotransporter gene ex ...... secretory capacity by butyrate
@en
Na-K-2Cl cotransporter gene ex ...... ecretory capacity by butyrate.
@nl
type
label
Na-K-2Cl cotransporter gene ex ...... secretory capacity by butyrate
@en
Na-K-2Cl cotransporter gene ex ...... ecretory capacity by butyrate.
@nl
prefLabel
Na-K-2Cl cotransporter gene ex ...... secretory capacity by butyrate
@en
Na-K-2Cl cotransporter gene ex ...... ecretory capacity by butyrate.
@nl
P2093
P2860
P356
P1476
Na-K-2Cl cotransporter gene ex ...... secretory capacity by butyrate
@en
P2093
P2860
P304
P356
10.1172/JCI1042
P407
P577
1998-05-01T00:00:00Z