Myocardial lipid accumulation in patients with pressure-overloaded heart and metabolic syndrome.
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Feeding a protein-restricted diet during pregnancy induces altered epigenetic regulation of peroxisomal proliferator-activated receptor-α in the heart of the offspringIn obese Zucker rats, lipids accumulate in the heart despite normal mitochondrial content, morphology and long-chain fatty acid oxidationEchocardiographic and Histologic Correlations in Patients with Severe Aortic Stenosis: Influence of Overweight and Obesity.PPARγ-induced cardiolipotoxicity in mice is ameliorated by PPARα deficiency despite increases in fatty acid oxidation.Effects of PPARs agonists on cardiac metabolism in littermate and cardiomyocyte-specific PPAR-γ-knockout (CM-PGKO) mice.Western diet changes cardiac acyl-CoA composition in obese rats: a potential role for hepatic lipogenesis.Cardiac steatosis potentiates angiotensin II effects in the heart.Cardiomyocyte triglyceride accumulation and reduced ventricular function in mice with obesity reflect increased long chain Fatty Acid uptake and de novo Fatty Acid synthesis.Mice with cardiac overexpression of peroxisome proliferator-activated receptor γ have impaired repolarization and spontaneous fatal ventricular arrhythmiasMyocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunctionMechanisms of lipotoxicity in the cardiovascular system.Chronic Hyperinsulinemia Causes Selective Insulin Resistance and Down-regulates Uncoupling Protein 3 (UCP3) through the Activation of Sterol Regulatory Element-binding Protein (SREBP)-1 Transcription Factor in the Mouse HeartMisregulation of PPAR Functioning and Its Pathogenic Consequences Associated with Nonalcoholic Fatty Liver Disease in Human Obesity.Comparative proteomics reveals abnormal binding of ATGL and dysferlin on lipid droplets from pressure overload-induced dysfunctional rat heartsInhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice.Fish oil selectively improves heart function in a mouse model of lipid-induced cardiomyopathyAldose Reductase Acts as a Selective Derepressor of PPARγ and the Retinoic Acid Receptor.Insulin resistance: metabolic mechanisms and consequences in the heart.Long-chain monounsaturated Fatty acids and incidence of congestive heart failure in 2 prospective cohortsEarly structural and metabolic cardiac remodelling in response to inducible adipose triglyceride lipase ablation.CHIP protects against cardiac pressure overload through regulation of AMPK.Effects of age and aerobic fitness on myocardial lipid content.Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy.Creating and curing fatty hearts.Lipoprotein lipase activity is required for cardiac lipid droplet production.PPARs: diverse regulators in energy metabolism and metabolic diseases.Lipid Use and Misuse by the Heart.Association of lipids with incident heart failure among adults with and without diabetes mellitus: Multiethnic Study of Atherosclerosis.Expression of Sterol Regulatory Element-Binding Proteins in epicardial adipose tissue in patients with coronary artery disease and diabetes mellitus: preliminary study.Lipotoxicity in type 2 diabetic cardiomyopathy.Lipid metabolism and toxicity in the heart.The impacts of obesity on the cardiovascular and renal systems: cascade of events and therapeutic approaches.PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease. Part II: PPAR-β/δ and PPAR-γ.The Transcription Profile Unveils the Cardioprotective Effect of Aspalathin against Lipid Toxicity in an In Vitro H9c2 Model.Fuel availability and fate in cardiac metabolism: A tale of two substrates.Transcriptome profiling reveals novel BMI- and sex-specific gene expression signatures for human cardiac hypertrophy.The role of ER stress in lipid metabolism and lipotoxicity.Age-dependent development of left ventricular wall thickness in type 2 diabetic (db/db) mice is associated with elevated low-density lipoprotein and triglyceride serum levels.Exposure to Amphetamines Leads to Development of Amphetamine Type Stimulants Associated Cardiomyopathy (ATSAC).MicroRNAs 33, 122, and 208: a potential novel targets in the treatment of obesity, diabetes, and heart-related diseases.
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Myocardial lipid accumulation in patients with pressure-overloaded heart and metabolic syndrome.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 24 May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Myocardial lipid accumulation ...... heart and metabolic syndrome.
@en
Myocardial lipid accumulation ...... heart and metabolic syndrome.
@nl
type
label
Myocardial lipid accumulation ...... heart and metabolic syndrome.
@en
Myocardial lipid accumulation ...... heart and metabolic syndrome.
@nl
prefLabel
Myocardial lipid accumulation ...... heart and metabolic syndrome.
@en
Myocardial lipid accumulation ...... heart and metabolic syndrome.
@nl
P2093
P2860
P50
P1476
Myocardial lipid accumulation ...... heart and metabolic syndrome.
@en
P2093
Clara Di Filippo
Federico Cacciapuoti
Franca Ferraraccio
Francesco Rossi
Mario Siniscalchi
Michele Portoghese
Raffaele Marfella
P2860
P304
P356
10.1194/JLR.P900032-JLR200
P577
2009-05-24T00:00:00Z