Epidermal growth factor receptor pathway analysis identifies amphiregulin as a key factor for cisplatin resistance of human breast cancer cells. - Wikidata - wikimedia - TriplyDB

Epidermal growth factor receptor pathway analysis identifies amphiregulin as a key factor for cisplatin resistance of human breast cancer cells.

Epidermal growth factor receptor pathway analysis identifies amphiregulin as a key factor for cisplatin resistance of human breast cancer cells.

http://www.wikidata.org/entity/Q37383705

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EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells FOXM1 confers acquired cisplatin resistance in breast cancer cells Potential targets for ovarian clear cell carcinoma: a review of updates and future perspectives Steering tumor progression through the transcriptional response to growth factors and stroma Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy Correlation between Trop2 and amphiregulin coexpression and overall survival in gastric cancer Amphiregulin promotes BAX inhibition and resistance to gefitinib in non-small-cell lung cancers.Amphiregulin and PTEN evoke a multimodal mechanism of acquired resistance to PI3K inhibition Tailored cancer immunotherapy using combinations of chemotherapy and a mixture of antibodies against EGF-receptor ligands.Genome wide proteomics of ERBB2 and EGFR and other oncogenic pathways in inflammatory breast cancer.Overexpression and activation of epidermal growth factor receptor in hemangioblastomas.Amphiregulin mediates estrogen, progesterone, and EGFR signaling in the normal rat mammary gland and in hormone-dependent rat mammary cancers.Growth differentiation factor 15 (GDF-15) plasma levels increase during bleomycin- and cisplatin-based treatment of testicular cancer patients and relate to endothelial damage.CCR9-CCL25 interactions promote cisplatin resistance in breast cancer cell through Akt activation in a PI3K-dependent and FAK-independent fashion.CD43 promotes cells transformation by preventing merlin-mediated contact inhibition of growth Erlotinib-cisplatin combination inhibits growth and angiogenesis through c-MYC and HIF-1α in EGFR-mutated lung cancer in vitro and in vivo.Platinum resistance in breast and ovarian cancer cell lines MiR-34a suppresses amphiregulin and tumor metastatic potential of head and neck squamous cell carcinoma (HNSCC)The Development of an Angiogenic Protein "Signature" in Ovarian Cancer Ascites as a Tool for Biologic and Prognostic Profiling.ADAM12 induces estrogen-independence in breast cancer cells.Interferon regulatory factor 4 binding protein is a novel p53 target gene and suppresses cisplatin-induced apoptosis of breast cancer cells.Role of mTOR in anticancer drug resistance: perspectives for improved drug treatment.Functional selectivity of EGF family peptide growth factors: implications for cancer.Epidermal growth factor (EGF) receptor-ligand based molecular staging predicts prognosis in head and neck squamous cell carcinoma partly due to deregulated EGF- induced amphiregulin expression.Combination of cisplatin and bromelain exerts synergistic cytotoxic effects against breast cancer cell line MDA-MB-231 in vitro Clinical pharmacology of tyrosine kinase inhibitors becoming generic drugs: the regulatory perspective Abnormal amphiregulin expression correlates with gastric cancer prognosis."Overcoming breast cancer drug resistance with mTOR inhibitors". Could it be a myth or a real possibility in the short-term future?Receptor tyrosine kinases and their activation in melanoma.miRNA-34c-5p inhibits amphiregulin-induced ovarian cancer stemness and drug resistance via downregulation of the AREG-EGFR-ERK pathway.MAP Kinases and Prostate Cancer.Dielectrophoresis-based cellular microarray chip for anticancer drug screening in perfusion microenvironments.Insulin-like growth factor-1 receptor inhibition overcomes gefitinib resistance in mucinous lung adenocarcinoma.Analysis of Constitutive EGFR Signaling Regulating IRF3 Transcriptional Activity in Cancer Cells.ErbB Receptors and Cancer.Transgenic mice specifically expressing amphiregulin in white adipose tissue showed less adipose tissue mass.An antibody to amphiregulin, an abundant growth factor in patients' fluids, inhibits ovarian tumors.Inhibition of the PI3K but not the MEK/ERK pathway sensitizes human glioma cells to alkylating drugs.ER-α36 mediates cisplatin resistance in breast cancer cells through EGFR/HER-2/ERK signaling pathway.Thioredoxin Confers Intrinsic Resistance to Cytostatic Drugs in Human Glioma Cells

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Epidermal growth factor receptor pathway analysis identifies amphiregulin as a key factor for cisplatin resistance of human breast cancer cells.

http://www.wikidata.org/entity/Q37383705

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2007 nî lūn-bûn

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Epidermal growth factor recept ...... of human breast cancer cells.

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Epidermal growth factor recept ...... of human breast cancer cells.

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Epidermal growth factor recept ...... of human breast cancer cells.

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Adi F Gazdar

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Di Cai

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Hans-Dieter Royer

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John D Minna

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Kati Servan

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Luc Girard

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Ulrich Jaehde

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P2860

Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells

Amphiregulin: a bifunctional growth-modulating glycoprotein produced by the phorbol 12-myristate 13-acetate-treated human breast adenocarcinoma cell line MCF-7

AKT/PKB signaling: navigating downstream

The docking protein Gab1 is the primary mediator of EGF-stimulated activation of the PI-3K/Akt cell survival pathway

Differential responses to doxorubicin-induced phosphorylation and activation of Akt in human breast cancer cells.

Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin

Untangling the ErbB signalling network

A differential requirement for the COOH-terminal region of the epidermal growth factor (EGF) receptor in amphiregulin and EGF mitogenic signaling

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10.1074/JBC.M706287200

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283

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Georg von Jonquieres

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